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Microwave-Assisted Synthesis and Functionalization of 2-Pyridones, 2-Quinolones and Other Ring-Fused 2-Pyridones
2-pyridones are important heterocycles with great applicability in medicinal chemistry and this core structure can be found in compounds with...
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Simultaneous determination of four quinolones in honey by nickel/aluminum-layered double hydroxide-based air-assisted dispersive solid-phase extraction and high-performance liquid chromatography
A novel air-assisted dispersive solid-phase extraction method based on nickel/aluminum-layered double hydroxides combined with high performance...
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Ionic liquid-based dispersive liquid–liquid microextraction followed by magnetic solid-phase extraction for determination of quinolones
An ionic liquid-based dispersive liquid–liquid microextraction (IL-DLLME) combined with magnetic solid-phase extraction (MSPE) was developed for...
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Sorption-Fluorimetric Determination of Quinolones in Waste and Natural Waters with a Smartphone
AbstractA simple, affordable, and safe (green chemistry) method is proposed for determining 17 quinolone antibiotics in waste and natural waters by...
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Facile synthesis of new pyrano[3,2-c]quinolones via the reaction of quinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile
Synthesis of heteroannulated pyrano[3,2- c ]quinolones was established starting from the reaction of 4-hydroxyquinolin-2-ones with...
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Design, Synthesis, SAR, Pharmacokinetic Prediction of New 4-Quinolones as Anti-Microbial Agents
Abstracts of new 4-quinolone derivatives was synthesized by conventional heating method. For the synthesized compounds, we performed pharmacokinetic...
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Development and validation of an LC-HRMS method for the determination of pyrrolizidine alkaloids and quinolones in honey employing a simple alkaline sample dilution
Honey residue and contaminant assessments are extremely important, as they deal with food and therapeutic safety issues of a widely consumed animal...
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Solid-Phase-Fluorimetric Determination of Quinolones in Medicinal Preparations on Cellulose Paper and in a Thin Silica Layer Using a Smartphone
AbstractA simple and an available method is proposed for the determination of quinolone antibiotics using solid-phase fluorescence digital...
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Facile synthesis of 5-aminopyrazolo-quinolones
Catalyzed by triethylamine, 4-hydrazino-quinolin-2-one derivatives and 2-(1-ethoxy-substituted-ene)malononitrile were refluxed together in ethanol to...
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Determination of 12 quinolones in honey by vortex-assisted dispersive liquid liquid microextraction performed in syringe based on deep eutectic solvent combine with ultra performance liquid chromatography-mass spectrometry
A novel vortex-assisted dispersive liquid–liquid microextraction method based on deep eutectic solvent (VA–DLLME–DES) completed in syringe has been...
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Noncovalent interactions as a solution for the metal-free one-pot asymmetric synthesis of (S)-2-aryl-2,3-dihydro-4(1H)-quinolones
4-Quinolones compose a remarkable class of compounds that show various pharmacological applications. In particular, the activities of both ( S ) and ( R )...
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Rapid Detection of Quinolone Antibiotics in Aquatic Products by Surface-Enhanced Raman Spectroscopy Combined with Thin Layer Chromatography
AbstractThis study presents the establishment of surface-enhanced Raman spectroscopy ( SERS ) combined with the thin-layer chromatography ( TLC ) method...
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Chitosan@Tannic Acid-Supported Fe3O4 Magnetic Bionanocomposite as Green and Recyclable Catalyst for the Synthesis of Benzo[g]thiazolo[3,2-a]quinolones Based on Nitroketene N,S-Acetal
To prepare an efficient magnetic bionanocomposite and to protect ferrite nanoparticles from oxidation and aggregation, the prepared Fe 3 O 4 was...
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Novel Synthetic Antibacterial Agents
Classical (fermentation-based) and nonclassical (nonfermentation-based) antibacterials are conventionally used for the treatment of bacterial...
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Post‐synthetic modification of IR-MOF‐3 as acidic-basic heterogeneous catalyst for one-pot synthesis of pyrimido[4,5-b]quinolones
In this study, a modified IR-MOF-3 via a multi-step post-synthesis modification, namely IR-MOF-3-ILOAc-Fe(acac) 3 , was prepared as an ion-pair...
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Topological analysis and reactivity study of monomeric and dimeric forms of 2-methyl-4(1H)-quinolone: a computational study
ContextQuinolone derivatives have gathered major attention largely due to their wonderful biological activities. Quinolones are a class of molecules...
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Preparation of a hydrophobic deep eutectic solvent and its application in the detection of quinolone residues in cattle urine
Enrichment for the detection of quinolone residues is usually cumbersome and requires large amounts of toxic organic reagents. Therefore, this study...
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Biosynthetic flexibility of Pseudomonas aeruginosa leads to hydroxylated 2-alkylquinolones with proinflammatory host response
The human pathogen Pseudomonas aeruginosa produces various 4(1 H )-quinolones with diverse functions. Among these, 2-nonyl-4(1 H )-quinolone (NQ) and its N ...
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QSRR modeling of the chromatographic retention behavior of some quinolone and sulfonamide antibacterial agents using firefly algorithm coupled to support vector machine
Quinolone and sulfonamide are two classes of antibacterial agents with an opulent history of medicinal chemistry features that contribute to their...
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Determination of Residual Amounts of Antibiotics in Environmental Samples and Food Products
AbstractWe present a review of methods for the sample preparation and determination of residual amounts of antibiotics in environmental samples and...
