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Chapter
An Overview on Chitosan-Based Adjuvant/Vaccine Delivery Systems
Vaccination is a highly effective and safe method in preventing life-threatening infections in both human and animals. It is based on the principle of activating the immune system and providing protection agai...
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Delivery of Biomolecules Using Chitosan Wound Dressings
The role of wound dressings has significantly transformed from by providing a simple protective function to dressings that actively participate in every stage of the wound healing process. Chitosan is one of t...
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Generations of Chitosan: The Progress in Drug Delivery
The discovery of sulfhydryl-modified polymers named thiomers in the late twentieth century resulted in a reframing conceptualization of polymers and their pharmaceutical use. As it is well known, the mucosal b...
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Chitosan and Its Potential Use for the Delivery of Bioactive Molecules in Bone Tissue Engineering
Bone tissue engineering (BTE) is a transitional research field that focuses on material science and biology to construct novel biocomposites proficient in treating impaired bone. Bioactive molecules are unique...
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3D-Printed Chitosan Composites for Biomedical Applications
Regeneration of defective or diseased tissue by 3D-printed biomaterials is an emerging area of research, and 3D printing technology will meet the shortage of organ transplantation and therapeutic clinical appl...
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Enhanced Topical Delivery of Drugs to the Eye Using Chitosan Based Systems
Topical administration is considered to be the favored route for ocular drug delivery by virtue of drug penetration into the underlying layers of eye. Targeted delivery of drugs to the ocular tissues especiall...
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Chapter
Chitosan Based Biomaterials for Periodontal Therapy
Periodontal diseases remain one of the major causes for tooth loss. Untreated periodontal disease could be debilitating for an individual and it could also lead to various other systemic health issues such as ...
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Chitosan Polymeric Micelles as Oral Delivery Platform of Hydrophobic Anticancer Drugs
Oral drug administration is the most common and preferred route of administration for both patients and doctors. However, some drugs, as the case of hydrophobic anticancer drugs, cannot be administered orally ...
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Chitosan-Based Theranostics for Cancer Therapy
Chitosan, a natural-based cationic polysaccharide, has a great potential to be utilized as drug delivery systems, tissue engineering scaffolds, and wound dressings due to its biocompatibility, bioactivity, bio...
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Chapter
Different Forms of Chitosan and Its Derivatives as Hemostatic Agent and Tissue Sealants
Hemorrhage is the leading cause of death in combat settings, trauma injury, and during surgical procedures. Hemostatic agents and tissue sealants are required when body’s coagulation cascade is not able to con...
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Application of Chitosan and Its Derivatives in Transdermal Drug Delivery
Chitosan is a natural polymer having much use in drug delivery applications. The polymer is characterized by its biocompatibility, biodegradability, muco-adhesiveness, antimicrobial activity, non-toxicity and ...
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Chapter
Recent Progress in Biomedical Applications of Chitosan Derivatives as Gene Carrier
Appropriate gene carriers are vital components of gene therapy for treating numerous intractable diseases. Compared with viral carriers, non-viral carriers exhibit lower immunogenicity and higher biosafety, wh...
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Chapter
Chitosan Nanofibers in Regenerative Medicine
Chitosan, a natural biopolymer, has been widely explored in the field of biomedical engineering. Because of its chemical similarity to the extracellular matrix (ECM) components, chitosan is known to be extreme...
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Chapter
Nanoparticles for Tissue Engineering: Type, Properties, and Characterization
The multidisciplinary area of tissue engineering unifies various fields such as medical biology, engineering, and material science that focus on develo** biological alternatives to increase the functions of ...
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Application of Nanoparticles in Soft Tissue Engineering
Tissue engineering is an interdisciplinary approach that integrates several fields of study such as biology, biochemistry, chemistry, nanotechnology, engineering, and material science. Three components are com...
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Chapter
Biomimetic via Exosome Mimetics in Regenerative Medicine and Therapeutics
Over the years, the field of regenerative medicine and therapeutics has witnessed several modifications in terms of the delivery vehicle used and their complex engineering to achieve the targeted drug/cargo de...
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Chapter
Strategies to Improve Delivery of Bioactive Agents
The delivery of bioactive agents/drugs in disease therapy and its improper disposal is one of the major causes of the constant rise in pollution levels. The majority of these factors depend upon alternative ap...
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Chapter
Role of Polymeric Nanomaterial in Regenerative Medicine and Stem Cell Biology
The combination of nanoparticles (NPs) and stem cells have been extensively investigated in regenerative medicine. Different types of NPs have been designed using various strategies that work very proficiently...
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Chapter
Challenges and Future Prospect of Nanoparticles in Tissue Engineering
Tissue engineering (TE) is a process where the damaged tissues and organs are recovered in a natural process using the patient’s physiological system. This involves fully repairing or regenerating damaged orga...
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Chapter
3D Bioprinting: A Short Overview and Future Prospects in Healthcare Engineering
The introduction of 3D Bioprinting in the fields of tissue engineering (TE) and regenerative medicine (RM) has significantly improved our ability to emulate the complex structural and functional organization o...