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Application of Nanoparticles in Soft Tissue Engineering

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Application of Nanoparticles in Tissue Engineering

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Abstract

Tissue engineering is an interdisciplinary approach that integrates several fields of study such as biology, biochemistry, chemistry, nanotechnology, engineering, and material science. Three components are commonly found in tissue engineering: cells that are capable of tissue repair, a scaffold that supports the proliferation of the cells impregnated on them, and bioactive molecules that will synchronize the architecture of desired tissue. The challenging task of tissue engineering is a scarcity of suitable biomaterial for scaffold formation, below-par proliferation of the cells on the scaffolds, controlled delivery of bioactive components in accordance with the requirement of the cells and lack of techniques that enable the formation of the suitable 3D architecture of the tissue. Size-dependent unique physiochemical properties of the nanoparticles could potentially fill the gaps in tissue engineering research. Nanoparticles and the nanomaterials such as nanotubes, nanowires, and nanowhiskers have been successfully engineered to produce suitable scaffolds that provide a distinct environment for individual cell types to proliferate and differentiate into matured tissues. This chapter presents an overview of the application of nanomaterials and the challenges involved in the application of nanomaterials in tissue engineering.

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Authors and Affiliations

  1. Department of Genetic engineering, SRM IST, Chennai, Tamil Nadu, India

    N. S. Raja

  2. Department of Microbiology and Molecular Genetics, The Institution for Medical Research Israel and Canada, The Hebrew University of Jerusalem, Jerusalem, Israel

    Manish Dash

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  1. N. S. Raja
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  2. Manish Dash
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  1. Department of Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia

    Sarah Afaq

  2. Department of Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia

    Arshi Malik

  3. Center for Interdisciplinary Research in Basic Sciences (CIRBSc), Jamia Millia Islamia, Delhi, India

    Mohammed Tarique

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Raja, N.S., Dash, M. (2022). Application of Nanoparticles in Soft Tissue Engineering. In: Afaq, S., Malik, A., Tarique, M. (eds) Application of Nanoparticles in Tissue Engineering. Springer, Singapore. https://doi.org/10.1007/978-981-16-6198-3_3

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