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  1. No Access

    Chapter

    Carboxymethyl Chitosan for Drug and Vaccine Delivery: An Overview

    Chitosan is a biopolymer derived from natural chitin, which is the principal component of the exoskeletons of crustaceans and insects as well as of the cell walls of some bacteria and fungi. Like cellulose, it...

    Selin Parmaksız, Sevda Şenel in Multifaceted Carboxymethyl Chitosan Deriva… (2024)

  2. Article

    Current status and future of delivery systems for prevention and treatment of infections in the oral cavity

    Oral health reflects the general health, and it is fundamental to well-being and quality of life. An infection in the oral cavity can be associated with serious complications in human health. Local therapy of ...

    Sevda Şenel, Ayben Işılay Özdoğan, Gülçin Akca in Drug Delivery and Translational Research (2021)

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    Article

    Mucoadhesive bilayered buccal platform for antifungal drug delivery into the oral cavity

    A drug delivery technology comprising a mucoadhesive bilayered buccally anchored tablet containing natamycin was developed. The concept was to anchor the tablet to the buccal tissue and allow controlled releas...

    Burcum Uzunoğlu, Clive G. Wilson in Drug Delivery and Translational Research (2021)

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    Chapter

    An Overview on Chitosan-Based Adjuvant/Vaccine Delivery Systems

    Vaccination is a highly effective and safe method in preventing life-threatening infections in both human and animals. It is based on the principle of activating the immune system and providing protection agai...

    Selin Parmaksız, Sevda Şenel in Chitosan for Biomaterials IV (2021)

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    Article

    Chitosan-based particulate systems for drug and vaccine delivery in the treatment and prevention of neglected tropical diseases

    Neglected tropical diseases (NTDs) are a diverse group of infections which are difficult to prevent or control, affecting impoverished communities that are unique to tropical or subtropical regions. In spite o...

    Sevda Şenel, Selin Yüksel in Drug Delivery and Translational Research (2020)

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    Chapter

    Application of Chitosan Based Scaffolds for Drug Delivery and Tissue Engineering in Dentistry

    is a marine polymer, which possesses numerous favorable properties including bioadhesivity, biodegradability and biocompatibility, which have enabled its use in and tissue engineering. Furthermore, has be...

    Sevda Şenel, Eda Ayşe Aksoy, Gülçin Akca in Marine-Derived Biomaterials for Tissue Eng… (2019)

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    Article

    Comparison of different types and sources of chitosan for the treatment of infections in the oral cavity

    Various formulation strategies have been investigated for non-invasive delivery of antimicrobials into the oral cavity for the treatment of the oral infections. In general, mucoadhesive polymers have been used...

    Gülçin Akca, Ayşe Özdemir, Z. Gülşen Öner in Research on Chemical Intermediates (2018)

  8. No Access

    Chapter

    Buccal Delivery of Biopharmaceuticals: Vaccines and Allergens

    Oral delivery of most biopharmaceuticals is limited due to their acidic and enzymatic degradation in the gastrointestinal tract. Furthermore, the high molecular weight of these drugs often results in poor abso...

    Sevda Şenel, Merve Cansız, Michael J. Rathbone in Mucosal Delivery of Biopharmaceuticals (2014)

  9. Chapter

    Fundamentals of Vaccine Delivery in Infectious Diseases

    Infectious diseases continue to be the major causes of illness, disability, and death. Moreover, in recent years, new infectious agents and diseases are being identified, and some diseases that were previously...

    Sevda Şenel in Fundamentals and Applications of Controlled Release Drug Delivery (2012)

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    Chapter

    Chitosan-Based Particulate Systems for Non-Invasive Vaccine Delivery

    The use of particulate systems is considered very promising for the delivery of antigenic molecules via parenteral and non-parenteral routes. They provide improved protection and facilitated transport of the a...

    Sevda Şenel in Chitosan for Biomaterials I (2011)

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    Article

    Preparation and investigation of the tenoxicam/β-cyclodextrin complex

    A complex of tenoxicam withβ-cyclodextrin was prepared by using co-grinding and freeze drying methods. The resulting products were studied by the solubility method, ultraviolet and infrared spectroscopy, differen...

    Sevda Şenel, Önder Çakoĝlu, Murat Şumnu in Journal of inclusion phenomena and molecul… (1992)

  12. No Access

    Article

    Formulation, Bioavailability, and Pharmacokinetics of Sustained-Release Potassium Chloride Tablets

    The release of potassium chloride incorporated into hydrogenated vegetable oil and hydroxypropyl methylcellulose matrix tablets was studied in vitro. The formulations containing 20% hydrogenated vegetable oil and...

    Sevda Şenel, Yilmaz Çapan, Turgay Dalkara, Neriman İnanç in Pharmaceutical Research (1991)