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Biomimetic via Exosome Mimetics in Regenerative Medicine and Therapeutics

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Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery

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Abstract

Over the years, the field of regenerative medicine and therapeutics has witnessed several modifications in terms of the delivery vehicle used and their complex engineering to achieve the targeted drug/cargo delivery. The intention to gain enhanced accuracy in the therapeutic usages is the major reason behind the change. The use of synthetic nanomaterials had gained momentum during the past few decades. However, due to the issues involved like poor biocompatibility, cytotoxicity, stability, etc. their use has been limited. That is why the modern day therapeutics has shifted its gear towards a more natural option of delivery system, which is termed as biomimetic. There are several options nowadays for the biomimetic cargo delivery vehicles which are summarized briefly in this chapter with a major focus towards exosomes has been given. Starting from their synthesis methods to their contribution in modern day medicine has been described briefly. Also a comparative analysis has been done among these nanosystems to prove the superiority of exosomes above all. Towards the end, the current challenges involved in these formulations have been depicted.

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Authors and Affiliations

  1. Institute of Life Sciences, Bhubaneswar, Odisha, India

    Sasmita Samal & Mamoni Dash

  2. School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, Odisha, India

    Sasmita Samal

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  1. Institute of Life Sciences, Bhubaneswar, Odisha, India

    Mamoni Dash

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Samal, S., Dash, M. (2022). Biomimetic via Exosome Mimetics in Regenerative Medicine and Therapeutics. In: Dash, M. (eds) Biomimetic Biomaterials for Tissue Regeneration and Drug Delivery. Springer, Singapore. https://doi.org/10.1007/978-981-16-4566-2_2

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