48 Result(s)
within
I. I. Agapov
English
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Article
Hydrogels Based on Recombinant Spidroin Stimulate Proliferation and Migration of Human Corneal Cells
The effect of recombinant spidroin (RS) hydrogel (HG) on anterior epithelial cells and keratocytes of the human cornea was studied in vitro. Corneal injuries are highly prevalent in develo** countries accord...
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Article
Identification of Ultrastructural Details of the Astrocyte Process System in Nervous Tissue of the Brain Using Correlative Scanning Probe and Transmission Electron Microscopy
Nanoscale morphological features of branched processes of glial cells may be of decisive importance for neuron–astrocyte interactions in health and disease. The paper presents the results of a correlation anal...
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Article
Correlative Fluorescent Scanning Probe Nanotomography Used to Study the Intracellular Distribution of Doxorubicin in MCF-7 Human Breast Adenocarcinoma Cells
Develo** technologies for efficient targeted drug delivery for oncotherapy requires new methods to analyze the features of micro- and nanoscale distributions of antitumor drugs in cells and tissues. A new ap...
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Article
Investigation of the Distribution of Magnetic Nanoparticles in Tumor Tissues by the Method of Scanning Magnetic Force Nanotomography
The development of effective biomedical technologies using magnetic nanoparticles (MNPs) for the tasks of oncotherapy and nanodiagnostics requires the development and implementation of new methods for the anal...
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Article
Scanning Optical Probe Nanotomography for Investigation of the Structure of Biomaterials and Cells
Creation of new effective bio-artificial structures for tissue engineering and regenerative medicine requires development and implementation of new technological approaches for analysis of micro- and nanostruc...
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Article
Surface Modification of Alginate Microcarriers for Improvement of Their Biological Properties
The obtaining of microcarriers for the cell culture and delivery is an urgent task of tissue engineering and regenerative medicine. The novel method of surface modification of alginate microcarriers in the for...
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Article
Nanoscale Correlation Analysis of the Morphological, Optical, and Magnetic Structure of Polymer Microspheres for Multiplex Diagnostics
A unified analytical technology based on the integration of scanning probe nanotomography and optical microscopy (SPNT–OM) is presented, and the potential of the technology is demonstrated by the example of a ...
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Article
Effect of Silk Fibroin on Neuroregeneration After Traumatic Brain Injury
Traumatic brain injury is one of the leading causes of disability among the working-age population worldwide. Despite attempts to develop neuroprotective therapeutic approaches, including pharmacological or ce...
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Article
Osteogenic differentiation of mouse bone marrow stromal cells on fibroin microcarriers
We investigated the proliferation and osteogenic differentiation of mesenchymal stem cells cultured on fibroin microcarriers. Effective cell proliferation on the surface of the microcarriers, determined by the...
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Article
Bioresorbable Scaffolds Based on Fibroin for Bone Tissue Regeneration
Using the tissue-engineered constructs based on scaffolds that imitate the extracellular matrix of living tissues unveils new opportunities in the treatment of various pathologies and injuries associated with ...
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Article
Regeneration of jejunal wall defect using an implant based on silk fibroin fibers
Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery,...
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Article
Nanostructural features of contacts of fibroblasts with dual-scale bioсompatible polyurethane scaffold
This paper presents a study of nanostructural features of contacts of bioprinted tissue spheroids with polyurethane dual scale biocompatible scaffold made by three-dimensional printing and electrospinning. Ana...
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Article
Effects of fibroin microcarriers on inflammation and regeneration of deep skin wounds in mice
The process of tissue regeneration following damage takes place with direct participation of the immune system. The use of biomaterials as scaffolds to facilitate healing of skin wounds is a new and interestin...
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Article
Changes in morphology of actin filaments and expression of alkaline phosphatase at 3D cultivation of MG-63 osteoblast-like cells on mineralized fibroin scaffolds
3D cultivation of MG-63 osteoblast-like cells on mineralized fibroin scaffolds leads to an increase in the expression of alkaline phosphatase, an early marker of bone formation. Increased expression is associa...
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Article
Erratum to: “Scanning Near-Field Optical Nanotomography: a New Method of Multiparametric 3D Investigation of Nanostructural Materials”
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Article
Biodegradable porous scaffolds for the bone tissue regeneration
Scaffolds made of recombinant spidroin and fibroin of Bombix mori silk were produced by the salt leaching technique. The regenerative properties of scaffold were evaluated in experiments with rats by implantation...
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Article
Scanning near-field optical nanotomography: a new method of multiparametric 3D investigation of nanostructural materials
A new experimental approach to multiparametric three-dimensional (3D) investigation of a broad class of composite nanostructural materials is developed on the basis of scanning near-field optical nanotomograph...
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Article
New Silk Fibroin-Based Bioresorbable Microcarriers
We fabricated bioresorbable microcarriers from water solution of Bombyx mori silk fi broin. The microcarriers are 3D structures with intricate surface and pores allowing penetration of culture medium, gas exchang...
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Article
Recombinant 1F9 spidroin microgels for murine full-thickness wound repairing
The study of the stimulating effect of the microgels (MGs) based on recombinant 1F9 spidroin on the regeneration of the deep skin wound in mice was carried out. The use of spidroin MGs was shown to increase si...
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Article
Erratum to: Scanning Probe Nanotomograph: Features of Engineering Solutions for Low-Temperature Analysis of Biomedical Materials
