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Article
Open AccessPreparing Modified Hyaluronic Acid with Tunable Content of Vinyl Groups for Use in Fabrication of Scaffolds by Photoinduced Crosslinking
Materials based on hyaluronic acid (HA) are extensively used in tissue engineering as scaffolds. Photoinduced crosslinking is one way to prepare them, and, for this, HA must be modified with vinyl groups, whic...
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Article
Open AccessUpconversion Nanoparticles Decorated with Polysialic Acid for Solid Tumors Visualization In Vivo
Upconversion nanoparticles (UCNPs) are a promising nanoplatform for bioreagent formation for in vivo imaging, which emit UV and blue light under the action of near-infrared radiation, providing deep tissue pen...
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Article
Upconversion Nanoparticles: Synthesis, Photoluminescence Properties, and Applications
In the late 1990s, the unique possibilities application of inorganic nanocrystals with anti-Stokes photoluminescence were demonstrated. In a fairly short period, a significant breakthrough has been achieved in...
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Article
Nanosized Anti-Stokes Phosphors for Antitumor Drug Delivery and Solid Tumor Theranostics
Abstract—Theranostics is the direction in modern biomedicine aimed at develo** drugs that combine the capabilities of diagnosis and therapy of tumors in one agent. Upconversion nanophosphors (UCNPs) are inor...
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Article
Nanoscale Correlation Analysis of the Morphological, Optical, and Magnetic Structure of Polymer Microspheres for Multiplex Diagnostics
A unified analytical technology based on the integration of scanning probe nanotomography and optical microscopy (SPNT–OM) is presented, and the potential of the technology is demonstrated by the example of a ...
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Article
Open AccessPhotodynamic therapy of melanoma by blue-light photoactivation of flavin mononucleotide
Melanoma is one of the most aggressive and lethal form of cancer. Photodynamic therapy (PDT) is a clinically approved technique for cancer treatment, including non-melanoma skin cancer. However, the most of co...
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Article
Three-Dimensional Luminescence Tomographic Visualization of Biological Tissues
We propose a method for obtaining a fluorescence tomographic image for visualization and diagnosis of tissues of a living organism. The method is based on the excitation of the luminescence of multicolor upcon...
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Article
Multifunctional polymer dispersions for biomedical assays obtained by heterophase radical polymerization
Methods for the preparation of multifunctional dispersions of polymer particles (DPP) in the course of free radical heterophase polymerization, which provides careful control of both macromolecular and colloid...
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Article
Open AccessRiboflavin photoactivation by upconversion nanoparticles for cancer treatment
Riboflavin (Rf) is a vitamin and endogenous photosensitizer capable to generate reactive oxygen species (ROS) under UV-blue irradiation and kill cancer cells, which are characterized by the enhanced uptake of ...
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Article
Dispersions of polyacrolein-based multifunctional microspheres for the creation of bioanalytical and visualizing reagents
The methods for preparation of polyacrolein-based dispersions of microspheres containing organic dyes and luminescent inorganic nanocrystals capable of light excitation in both the ultraviolet and the infrared...
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Article
Upconversion nanoparticles for tumor imaging with near-infrared radiation
Prospects for using upconversion nanoparticles as markers for tumor optical imaging are discussed. Using a model of epidermoid Lewis lung carcinoma engrafted in mice, luminescent signals from nanoparticles del...
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Article
Biocompatible upconversion ink for hidden anticounterfeit labeling
Ink for rapid the application of anticounterfeit labels by means of standard printing devices has been developed based on upconversion nanoparticles (nanophosphors). Printing ink is made of an aqueous dispersi...
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Article
Bioanalytical fluorescent reagents based on polyacrolein-containing particles labeled with semiconductor CdSe/ZnS nanocrystals
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Article
Immunochromatographic and latex-agglutination systems for diphtheria toxin detection
The use of two monoclonal antibody types specific to different epitopes of diphtheria toxin systems have been developed to reveal diphtheria corynebacteria toxigenicity rapidly based on immunochromatographic a...
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Article
Modification of solids with polymer nanolayers as a process for manufacture of novel biomaterials
The results of study on the chemical deposition of polymeric coatings of a nanoscale thickness on porous and flat inorganic matrices and encapsulation of nano-and microparticles in polymer shells are discussed...
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Article
Multicomponent thermosensitive systems for biocatalysts
Composite matrices based on macroporous silica modified by N-vinylcaprolactam copolymers with diallyldimethylammonium chloride and with 2-hydroxyethyl methacrylate were obtained. Lipase from Pseudomonas fluoresce...
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Article
The turbidimetric study of latex particle agglutination: Assay of 2,4-dichlorophenoxyacetic acid
By the example of 2,4-dichlorophenoxyacetic acid (2,4-D) assay by the inhibition of latex agglutination, new synthetic polymer microspheres for the conjugation with antibodies to 2,4-D and agglutinators based ...
