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Article
Osteogenic differentiation of mouse bone marrow stromal cells on fibroin microcarriers
We investigated the proliferation and osteogenic differentiation of mesenchymal stem cells cultured on fibroin microcarriers. Effective cell proliferation on the surface of the microcarriers, determined by the...
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Article
Regeneration of jejunal wall defect using an implant based on silk fibroin fibers
Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery,...
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Article
Changes in morphology of actin filaments and expression of alkaline phosphatase at 3D cultivation of MG-63 osteoblast-like cells on mineralized fibroin scaffolds
3D cultivation of MG-63 osteoblast-like cells on mineralized fibroin scaffolds leads to an increase in the expression of alkaline phosphatase, an early marker of bone formation. Increased expression is associa...
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Article
Recombinant 1F9 spidroin microgels for murine full-thickness wound repairing
The study of the stimulating effect of the microgels (MGs) based on recombinant 1F9 spidroin on the regeneration of the deep skin wound in mice was carried out. The use of spidroin MGs was shown to increase si...
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Article
Novel 3D-microcarriers from recombinant spidroin for regenerative medicine
Microcarriers generated from recombinant spidroin 1F9 are suitable for use as an injection material. The microcarriers were a heterogeneous mixture of microgel particles ranging from 50 to 300 µm in size with ...
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Article
Relationship between Gelatin Concentrations in Silk Fibroin-Based Composite Scaffolds and Adhesion and Proliferation of Mouse Embryo Fibroblasts
Porous scaffolds of silk fibroin and composite porous scaffolds with 10, 20, 30, 40, and 50% gelatin were made by the freezing–thawing method. The relationship between adhesion and proliferation rate mouse emb...
