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Article
Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrLGlu activity
Methamphetamine (METH), an abused psychostimulant, impairs cognition through prolonged or even single-dose exposure, but animal experiments have shown contradictory effects on memory deficits. In this study we...
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Article
Open AccessA photocatalytic redox cycle over a polyimide catalyst drives efficient solar-to-H2O2 conversion
Circumventing the conventional two-electron oxygen reduction pathway remains a great problem in enhancing the efficiency of H2O2 photosynthesis. A promising approach to achieve outstanding photocatalytic activity...
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Article
Open AccessBiochar prevents soybean seedling injury caused by atrazine residue by regulating the concentration of this herbicide in soil pore water
The residue of atrazine in field soils poses a major threat to crop growth in the rotation system, raising concerns about grain security and food safety. Current agricultural production requires more efficient...
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Article
Regulating the crystal phase of bismuth-based semiconductors for promoted photocatalytic performance
Numerous bismuth-based semiconductors (BBSs) with sophisticated and desirable structures used as photocatalysts for efficient photocatalytic degradation of water organic contaminants have attracted considerabl...
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Article
Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
Nutrient handling is an essential function of the gastrointestinal tract. Hormonal responses of small intestinal enteroendocrine cells (EECs) have been extensively studied but much less is known about the role...
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Article
IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin α5/FAK in diabetic kidney disease
Podocyte apoptosis or loss is the pivotal pathological characteristic of diabetic kidney disease (DKD). Insulin-like growth factor-binding protein 2 (IGFBP2) have a proinflammatory and proapoptotic effect on d...
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Article
Open AccessIon pair sites for efficient electrochemical extraction of uranium in real nuclear wastewater
Electrochemical uranium extraction from nuclear wastewater represents an emerging strategy for recycling uranium resources. However, in nuclear fuel production which generates the majority of uranium-containin...
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Article
Open AccessProto-oncogene c-Myb potentiates cisplatin resistance of ovarian cancer cells by downregulating lncRNA NKILA and modulating cancer stemness and LIN28A-let7 axis
Ovarian cancer is a major gynecological cancer that has poor prognosis associated mainly to its late diagnosis. Cisplatin is an FDA approved ovarian cancer therapy and even though the therapy is initially prom...
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Article
Open AccessCanagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation
Pulmonary hypertension (PH) is a progressive fatal disease with no cure. Canagliflozin (CANA), a novel medication for diabetes, has been found to have remarkable cardiovascular benefits. However, few studies h...
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Article
Open AccessUniversity students’ concepts of nation in Mainland China, Hong Kong, and Macau: Patriotism or nationalism?
This study investigated the concepts of nation among university students in Mainland China, Hong Kong, and Macau. The findings revealed a lack of consistent patterns among university students’ perceptions of p...
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Article
Biochemical risk factors and outcomes of acute promyelocytic leukemia patients with thrombotic events: a matched pair analysis
Acute promyelocytic leukemia (APL) stands out as a distinctive form of acute leukemia, exhibiting a higher occurrence of thrombotic events when contrasted with other leukemia subtypes. Since thrombosis is a re...
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Article
ScRNA-seq of gastric cancer tissues reveals differences in the immune microenvironment of primary tumors and metastases
Gastric carcinoma (GC) is regarded as one of the deadliest cancer characterized by diversity and haste metastasis and suffers limited understanding of the spatial variation between primary and metastatic GC tu...
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Open AccessAuthor Correction: Cost-effective methylome sequencing of cell-free DNA for accurately detecting and locating cancer
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Article
Unlocking the potential of biochar: an iron-phosphorus-based composite modified adsorbent for adsorption of Pb(II) and Cd(II) in aqueous environments and response surface optimization of adsorption conditions
In this work, iron-phosphorus based composite biochar (FPBC) was prepared by modification with potassium phosphate and iron oxides for the removal of heavy metal ions from single and mixed heavy metal (Pb and ...
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Article
Open AccessPredicting equilibrium distributions for molecular systems with deep learning
Advances in deep learning have greatly improved structure prediction of molecules. However, many macroscopic observations that are important for real-world applications are not functions of a single molecular ...
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Article
Effect of Ba2+ on the biomineralization of Ca2+ and Mg2+ ions induced by Bacillus licheniformis
The effect of barium ions on the biomineralization of calcium and magnesium ions is often overlooked when utilizing microbial-induced carbonate precipitation technology for removing barium, calcium, and magnes...
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Article
Open AccessA near-zero quiescent power breeze wake-up anemometer based on a rolling-bearing triboelectric nanogenerator
Wind sensors have always played an irreplaceable role in environmental information monitoring and are expected to operate with lower power consumption to extend service lifetime. Here, we propose a breeze wake...
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Article
TXNIP Regulates NLRP3 Inflammasome-Induced Pyroptosis Related to Aging via cAMP/PKA and PI3K/Akt Signaling Pathways
Aging is an inevitable natural process with time-dependent dysfunction and the occurrence of various diseases, which impose heavy burdens on individuals, families, and society. It has been reported that NLRP3 ...
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Article
Open AccessSpatially organized cellular communities form the develo** human heart
The heart, which is the first organ to develop, is highly dependent on its form to function1,2. However, how diverse cardiac cell types spatially coordinate to create the complex morphological structures that are...
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Article
A guideline on the molecular ecosystem regulating ferroptosis
Ferroptosis, an intricately regulated form of cell death characterized by uncontrolled lipid peroxidation, has garnered substantial interest since this term was first coined in 2012. Recent years have witnesse...
