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Article
Open AccessAll-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury
A promising new therapy option for acute kidney injury (AKI) is mesenchymal stem cells (MSCs). However, there are several limitations to the use of MSCs, such as low rates of survival, limited homing capacity,...
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Article
IGFBP2 induces podocyte apoptosis promoted by mitochondrial damage via integrin α5/FAK in diabetic kidney disease
Podocyte apoptosis or loss is the pivotal pathological characteristic of diabetic kidney disease (DKD). Insulin-like growth factor-binding protein 2 (IGFBP2) have a proinflammatory and proapoptotic effect on d...
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Article
Open AccessComparison of the treatment efficacy of umbilical mesenchymal stem cell transplantation via renal subcapsular and parenchymal routes in AKI-CKD mice
Mesenchymal stem cells (MSCs) have emerged as a promising cell-based therapy for acute kidney injury (AKI). However, the optimal route of MSC transplantation remains controversial, and there have been no compa...
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Chapter and Conference Paper
Education Platform of Congenital Heart Disease Based on Mixed Reality Technology
Recently the Mixed Reality (MR) technology has a rapid development and strong application prospect in various fields. This technology has been successfully applied in clinical work by means of surgical navigat...