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Article
Open AccessSpatially organized cellular communities form the develo** human heart
The heart, which is the first organ to develop, is highly dependent on its form to function1,2. However, how diverse cardiac cell types spatially coordinate to create the complex morphological structures that are...
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Chapter and Conference Paper
Rolling Horizon Co-evolution for Snake AI Competition
The Snake game, a classic in the gaming world, gains new dimensions with the Snake AI competition, where two players controlled by AI algorithms can now compete simultaneously in the same game session. This co...
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Article
Open AccessThe value of serum Sema4D level in predicting the prognosis of patients with acute ST-segment elevation myocardial infarction and with high thrombus burden
Acute ST-segment elevation myocardial infarction (STEMI) is a serious cardiovascular disease. High thrombus burden is an independent risk factor for poor prognosis of acute myocardial infarction. However, ther...
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Article
Fatigue Properties and Life Prediction of GS80A Steel Under the Effect of Hydrogen-Rich Environment
To ensure the safety of high-strength bolt materials in an ocean hydrogen-rich environment, this work first studies the H-effect on GS80A steel by mechanical tests and fracture surface observations. The experi...
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Article
Open AccessfSDE: efficient evolutionary optimisation for many-objective aero-engine calibration
Engine calibration aims at simultaneously adjusting a set of parameters to ensure the performance of an engine under various working conditions using an engine simulator. Due to the large number of engine para...
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Article
Open AccessSin3a drives mesenchymal-to-epithelial transition through cooperating with Tet1 in somatic cell reprogramming
Identifying novel regulatory factors and uncovered mechanisms of somatic cell reprogramming will be helpful for basic research and clinical application of induced pluripotent stem cells (iPSCs). Sin3a, a multi...
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Chapter and Conference Paper
Simpler is Sometimes Better: A Dynamic Aero-Engine Calibration Study
Many real-world optimisation problems are in dynamic environments such that the search space and the optimum usually change over time. Various algorithms have been proposed in the literature to deal with such ...
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Chapter and Conference Paper
Fairer Machine Learning Through Multi-objective Evolutionary Learning
Dilemma between model accuracy and fairness in machine learning models has been shown theoretically and empirically. So far, dozens of fairness measures have been proposed, among which incompatibility and comp...
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Article
High-throughput-generating water-in-water droplet for monodisperse biocompatible particle synthesis
Water-in-water (W/W) droplets are biocompatible vessels for bioanalysis and biomolecules delivery. Due to the ultralow interfacial tension, the stable generation of W/W droplets still faces some challenges. In...
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Article
Open AccessPioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate
Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play key roles...
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Article
Visual and colorimetric determination of H2O2 and glucose based on citrate-promoted H2O2 sculpturing of silver nanoparticles
Isotropic silver nanoparticles (iAg NPs) can be easily prepared at low costs, have a low electrochemical potential and high extinction coefficient. An effective colorimetric assay for H2O2 is reported here based ...
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Article
Open AccessTemporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification
Malformations of the sympathetic nervous system have been associated with cardiovascular instability, gastrointestinal dysfunction, and neuroblastoma. A better understanding of the factors regulating sympathet...
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Chapter and Conference Paper
Effect of Solution Treatment on Microstructure and Mechanical Properties of HGH163 Alloy
Ni-based superalloy HGH163 wire was studied in this paper. The microstructure and properties of HGH163 wire subjected to different solution treatments were investigated by the mechanical properties testing, me...
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Chapter and Conference Paper
Weld Properties of Haynes214 Alloy
Haynes214 alloy should be welded together with other alloys when it is used as brush seal materials. In the present investigation the welding performance of Haynes214 alloy welded with GH4169 alloy and GH625 a...
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Article
Visual and photometric determination of histamine using unmodified gold nanoparticles
The authors describe a colorimetric approach for on-site monitoring of histamine based on the use of gold nanoparticles (AuNPs) that have a negatively charged surface due to the presence of adsorbed citrate io...
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Article
Separation of gold nanorods by viscosity gradient centrifugation
Size-uniform gold nanorods (Au-NRs) are used in biosensing, bioimaging, photothermal therapy, drug and gene delivery, and controlled release. Monodisperse Au-NRs are usually obtained by separation steps follow...
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Article
Installation Study on ITER Lower CC In-Pit ICFs
In the R&D process of the ITER lower correct coil (CC) in-pit in-cryostat-feeders (ICFs) system, various machining tasks and assembly procedure have been studied. The lower CC ICFs contains six feeder rings an...
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Article
Open AccessRequirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis
Neural crest defects lead to congenital heart disease involving outflow tract malformation. Integrin-linked-kinase (ILK) plays important roles in multiple cellular processes and embryogenesis. ILK is expressed...
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Article
Screening for Chip-Processing Potato Line from Introgression of Wild Species’ Germplasms with Post-Harvest Storage and Chip Qualities
The processing of potatoes into chips is expanding in China. There is a need for new processing cultivars that are well-suited for the local ecological environment. Eleven potato varieties were bred from hybri...
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Article
Preliminary proteomic analysis of human serum from patients with laryngeal carcinoma
To better evaluate the serum protein alterations in patients with laryngeal carcinoma during surgical treatment process, a comparative proteomic analysis of human serum from patients with laryngeal carcinoma b...
