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430 Result(s)
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Article
Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a central focus of immunotherapy to treat cancer. When CD8+ T cells specifically recognize antige...
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Article
Soil Organic Matter and Total Nitrogen Reshaped Root-Associated Bacteria Community and Synergistic Change the Stress Resistance of Codonopsis pilosula
The stress resistance of medicinal plants is essential to the accumulation of pharmacological active ingredients, but the regulation mechanism of biological factors and abiotic factors on medicinal plants is s...
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Article
Solvent-Free Enzymatic Synthesis of Ethyl 3-Oxobutyrate Derivative: Characterization and Optimization of Reaction Condition
It was first found that porcine pancreatic lipase (PPL) could catalyze the Knoevenagel condensation of aromatic aldehydes and ethyl acetoacetate under solvent-free conditions in this paper. Under solvent-free ...
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Article
The aging and color development of writing in paper archives
The most important value of archives lies in the handwritten information they record. However, during the storage process, handwriting may change color or fade due to the influence of the storage environment, ...
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Article
Surface Plasmon Transmission Line Based on Folded Stepped Grooves and Spiral-Shaped Structures
In this paper, a novel coplanar waveguide (CPW) spoof surface plasmon polariton (SSPP) transmission line (TL) is firstly proposed. The equivalent circuit model is established to analyze the effects of the fold...
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Article
Growth Stage-Dependent Variation in Soil Quality and Microbial Diversity of Ancient Gleditsia sinensis
The environment monitoring of forest is vital for the ecosystem sustainable management, especially soil quality. Ancient Gleditsia sinensis is one of the most distributed ancient trees in Shaanxi. Comprehensive s...
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Article
Polarization Properties in GaN Double-Channel HEMTs at Mid-Infrared Frequencies
The polarization properties of grating-gate GaN-based high electron mobility transistors in the mid-infrared region have been investigated. However, due to the lack of research on the absorption characteristic...
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Article
Deoxynivalenol Detoxification by a Novel Strain of Pichia kudriavzevii via Enzymatic Degradation and Cell Wall Adsorption
Deoxynivalenol (DON) is a mycotoxin that significantly threatens the food and feed industry. Corn steep liquor (CSL) is an acidic byproduct of the corn starch industry, and DON is concentrated in CSL once the ...
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Article
Clinical implications and mechanism of complement C1q in polymyositis
Polymyositis (PM) is the most common autoimmune disease in neurology and among muscle disorders; it is of great significance to thoroughly understand the mechanism of PM to find new diagnosis and treatment met...
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Article
Ultrahigh Sensitivity Surface Plasmonic Resonance Temperature Sensor Based on Polydimethylsiloxane-Coated Photonic Crystal Fiber
We propose and demonstrate a compact optical fiber temperature sensor based on surface plasmon resonance with high sensitivity and high figure of merit. This optical fiber temperature sensor uses a new photoni...
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Article
Recent Insights into the Roles of PEST‐Containing Nuclear Protein
PEST-containing nuclear protein (PCNP), a short-lived small nuclear protein with 178 amino acids, is a nuclear protein containing two PEST sequences. PCNP is highly expressed in several malignant tumors such a...
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Article
Heparanase accelerates the angiogenesis and inhibits the ferroptosis of p53-mutant non-small cell cancers in VEGF-dependent manner
The aim of this study is to explore the effects and specific mechanisms of heparanase on angiogenesis and iron deficiency anemia in TP53 mutant cancer. For this purpose, we conducted in vitro cell experiments ...
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Article
METTL3 Promotes OSCC Progression by Down-Regulating WEE1 in a m6A-YTHDF2-Dependent Manner
Oral squamous cell carcinoma (OSCC) is a common and highly lethal epithelial cancer. This study aimed to confirm the role of METTL3 in promoting OSCC and investigate its specific underlying mechanisms. Express...
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Article
Comprehensive Glycosylation Characterization of Recombinant Human Erythropoietin by Electron-Activated Dissociation Mass Spectrometry
Recombinant human erythropoietin (rhEPO) is a glycoprotein that acts as the main hormone involved in regulating red blood cell production to treat anemia caused by chronic kidney disease or chemotherapy, which...
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Article
Expression of Anoikis-Related Genes and Potential Biomarkers in Colon Cancer Based on RNA-seq and scRNA-seq
Colon cancer (CC) is a malignant tumor in the colon. Despite some progress in the early detection and treatment of CC in recent years, some patients still experience recurrence and metastasis. Therefore, it is...
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Article
Stenotrophomonas maltophilia Isolated from the Gut Symbiotic Community of the Plastic-Eating Tenebrio molitor
Polyvinyl chloride (PVC) waste is a major environmental challenge. In this study, we found that a PVC-eating insect, Tenebrio molitor, could survive by consuming PVC as a dietary supplement. To understand the gut...
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Article
LncRNA HOTAIR accelerates free fatty acid-induced inflammatory response in HepG2 cells by recruiting SRSF1 to stabilize MLXIPL mRNA
LncRNA HOTAIR has been reported to be associated with metabolic diseases of the liver. However, the effect of HOTAIR on non-alcoholic fatty liver disease (NAFLD) inflammation and its potential mechanism have n...
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Article
Synergetic Effect of Memecylon edule Mediated AuNPs and Ultrasound Therapy as a Promising Approach Against Proliferation of Pediatric Acute Leukemia Cell Lines
In the present work, an easy one-pot environmentally friendly method is demonstrated where the extract of Memecylon edule was utilized for the synthesis of gold nanoparticles (Au NPs) through the reduction of chl...
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Article
Effects of Cold Plasma Pretreatment on the Synthesis of Polysaccharide from Pleurotus ostreatus
Fungal polysaccharides have attracted wide attention because of their medical pharmaceutical and health care value. So far, many efforts have been made in strain improvement to produce polysaccharides on a lar...
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Article
Dynamic Tunable Bidirectional Excitation Multi-PIT Device for Terahertz Biosensing and Optical Switching
In this study, a multi-layered and bi-directionally excitable plasmon-induced transparency (PIT) device with multiple graphene layers was designed. The PIT window was regulated by controlling the Fermi level o...