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Article
Industrial Investigation on Inclusions and Solidification Structure of Steel Continuous Casting Slabs Under Mold Electromagnetic Stirring
In the current study, the quantity, size, and spatial distribution of non-metallic inclusions along the thickness direction of an ultralow carbon IF steel were detected employing an automatic SEM-EDS scanning ...
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Article
Open AccessIRGM/Irgm1 increases autophagy to inhibit activation of NLRP3 inflammasome in inflammatory injury induced acute liver failure
Immune-related GTPase M (IRGM) induces autophagy and suppresses inflammation, but its putative role and signaling mechanism remain undefined in the pathogenesis of liver failure. This study aimed to address ho...
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Article
Candidate gene mining of GA-mediated regulation of pear fruit shape
Fruit shape is one of the important traits for quality evaluation, classification, and market grading of horticultural crops. In order to explore the genes regulating pear fruit shape formation, pear varieties...
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Article
ZBTB16 inhibits DNA replication and induces cell cycle arrest by targeting WDHD1 transcription in lung adenocarcinoma
Lung adenocarcinoma is a malignant tumor with high morbidity and mortality. ZBTB16 plays a double role in various tumors; however, the potential mechanism of ZBTB16 in the pathophysiology of lung adenocarcinom...
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Article
GCNT3 Promotes Hepatocellular Carcinoma Progression and EMT by Activating the PI3K/AKT Pathway
Primary liver cancer, specifically hepatocellular carcinoma (HCC), is a major global health concern. GCNT3 has been identified as an oncogene in various human malignancies. This investigation aimed to discover...
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Article
Expression of Anoikis-Related Genes and Potential Biomarkers in Colon Cancer Based on RNA-seq and scRNA-seq
Colon cancer (CC) is a malignant tumor in the colon. Despite some progress in the early detection and treatment of CC in recent years, some patients still experience recurrence and metastasis. Therefore, it is...
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Article
Open AccessClonal expansion of shared T cell receptors reveals the existence of immune commonality among different lesions of synchronous multiple primary lung cancer
The increase in the detection rate of synchronous multiple primary lung cancer (MPLC) has posed remarkable clinical challenges due to the limited understanding of its pathogenesis and molecular features. Here,...
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Article
Open AccessEco-innovation and corporate waste management: The moderating role of ESG performance
Based on a sample of companies from G7 countries, we investigate the effect of eco-innovation on waste management as well as the moderating role of firms’ environmental, social, and governance (ESG) on this re...
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Article
The p38 MAPK/snail signaling axis participates in cadmium-induced lung cancer cell migration and invasiveness
To determine that p38 MAPK activation contributes to the migration and invasion of lung cancer cells caused by cadmium (Cd). A549 lung cancer cell migration and invasion were assessed using a transwell plate s...
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Article
STYXL1 promotes proliferation and epithelial mesenchymal transition of gastric cancer cells via activating the PI3K/AKT pathway
Gastric cancer (GC) is a common and grievous disorder with high heterogeneity. Serine/threonine/tyrosine-interacting-like protein 1 (STYXL1), a pseudophosphatase without catalytic activity, plays a important r...
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Article
Risk factors for short-term prognosis of end-stage liver disease complicated by invasive pulmonary aspergillosis
Patients with end-stage liver disease (ESLD) are susceptible to invasive pulmonary aspergillosis (IPA). This study aimed to investigate the risk factors affecting the occurrence and short-term prognosis of ESL...
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Article
miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway
Previous reports have confirmed that miR-206 participates in inflammatory cardiomyopathy, but its definite mechanism remains elusive. This study aims to elucidate the potential mechanism of miR-206 in septic c...
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Article
Open AccessDeep reinforcement learning based on balanced stratified prioritized experience replay for customer credit scoring in peer-to-peer lending
In recent years, deep reinforcement learning (DRL) models have been successfully utilised to solve various classification problems. However, these models have never been applied to customer credit scoring in p...
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Article
Open AccessSingle-cell profiling identifies IL1Bhi macrophages associated with inflammation in PD-1 inhibitor-induced inflammatory arthritis
Inflammatory arthritis (IA) is a common rheumatic adverse event following immune checkpoint inhibitors treatment. The clinical disparities between IA and rheumatoid arthritis (RA) imply disease heterogeneity a...
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Article
Open AccessDVA: predicting the functional impact of single nucleotide missense variants
In the past decade, single nucleotide variants (SNVs) have been identified as having a significant relationship with the development and treatment of diseases. Among them, prioritizing missense variants for fu...
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Article
Correction: miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway
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Article
Risk factors of unruptured intracranial aneurysms instability in the elderly
Presently, a consistent strategy for determining the stability of unruptured intracranial aneurysms (UIAs) in elderly patients is lacking, primarily due to the unique characteristics of this demographic. Our o...
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Chapter and Conference Paper
Detecting Critical Nodes in Hypergraphs via Hypergraph Convolutional Network
In many real-world networks, such as co-authorship, etc., relationships are complex and go beyond pairwise associations. Hypergraphs provide a flexible and natural modeling tool to model such complex relations...
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Chapter
A Basic Hypoplastic Model with Fabric Evolution
The fabric anisotropy has great impacts on the behaviour of granular soils but constitutive modelling considering fabric evolution still pose difficulties. In this paper, a hypoplastic constitutive model is de...
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Article
Open AccessSOX2 promotes vasculogenic mimicry by accelerating glycolysis via the lncRNA AC005392.2-GLUT1 axis in colorectal cancer
Vasculogenic mimicry (VM), a new model of angiogenesis, fulfills the metabolic demands of solid tumors and contributes to tumor aggressiveness. Our previous study demonstrated the effect of SOX2 in promoting V...
