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1,288 Result(s)
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Activation of MAL2 by RAD21 inhibits the expression of MHC-I in immune evasion of endometrial cancer
CD8+ T cells are the primary mediators of anticancer immunity, and modulation of the CD8+ T cell response has been a central focus of immunotherapy to treat cancer. When CD8+ T cells specifically recognize antige...
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Publisher Correction to: A predicted distribution for Galois groups of maximal unramified extensions
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A predicted distribution for Galois groups of maximal unramified extensions
We consider the distribution of the Galois groups Gal ( K ...
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Open AccessPhysical activity dynamically moderates the impact of multimorbidity on the trajectory of healthy aging over sixteen years
Research examining the healthy aging trajectory of retired older adults with multimorbidity is limited, leaving uncertainties regarding the optimal physical activity (PA) intensity and frequency necessary to s...
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Open AccessTwo cases of atrial myxoma with calcification and ossification as the main features
Cardiac myxomas are the most common type of primary cardiac tumors in adults, but they can have variable features that make them difficult to diagnose. We report two cases of atrial myxoma with calcification o...
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Open AccessNab-paclitaxel plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or recurrent cervical cancer
This study aimed to assess the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus platinum versus paclitaxel plus platinum as first-line therapy in patients with metastatic or r...
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Effect of soybean proteins and peptides on the growth and adhesive ability of Limosilactobacillus Reuteri DSM17938
Limosilactobacillus reuteri DSM17938 is one of the most pivotal probiotics, whose general beneficial effects on the intestinal microbiota are well recognized. Enhancing their growth and metabolic activity can eff...
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Effect of substrate orientation on the structures and properties of BiFe0.91Zr0.09O3 thin films
Utilizing MgO single crystal substrates with varied orientations (〈100〉, 〈110〉 and 〈111〉), BiFe0.91Zr0.09O3·(BFZO) films with diverse orientations were synthesized on LaNiO3·(LNO) underlying electrodes employing ...
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KnowDT: Empathetic dialogue generation with knowledge enhanced dependency tree
A human-like dialogue system should prioritize expressing empathy towards others, which entails two crucial aspects: (1) semantic cognition and (2) emotion detection. Previous approaches mainly model semantic ...
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The Role of HSP90 Molecular Chaperones in Depression: Potential Mechanisms
Major depressive disorder (MDD) is characterized by high rates of disability and death and has become a public health problem that threatens human life and health worldwide. HPA axis disorder and neuroinflamma...
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Open AccessForced vital capacity and body mass index of **njiang children and adolescents: an analysis based on seven successive national surveys, 1985–2014
Pulmonary function is very important for the healthy development of children and adolescents. However, fewer studies have been conducted on pulmonary function trends in children and adolescents in remote areas...
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Open AccessPredicting treatment response in multicenter non-small cell lung cancer patients based on federated learning
Multicenter non-small cell lung cancer (NSCLC) patient data is information-rich. However, its direct integration becomes exceptionally challenging due to constraints involving different healthcare organization...
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Open AccessRelationship between serum endothelin-1 and in-stent restenosis following vertebral artery stenting
The study objective was to investigate the relations between serum endothelin-1 and in-stent restenosis in vertebral artery stenting. Sixty-eight patients undergoing re-examination of vertebral artery stenting...
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Discovery of metal-binding proteins by thermal proteome profiling
Metal-binding proteins (MBPs) have various and important biological roles in all living species and many human diseases are intricately linked to dysfunctional MBPs. Here, we report a chemoproteomic method nam...
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Monolithic three-dimensional tier-by-tier integration via van der Waals lamination
Two-dimensional (2D) semiconductors have shown great potential for monolithic three-dimensional (M3D) integration due to their dangling-bonds-free surface and the ability to integrate to various substrates wit...
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Open AccessExploration of a method for insight into accessibility design flaws based on touch dynamics
The widespread use of smartphones implies that intelligent systems must address the negative emotions experienced by a diverse user group when encountering usability difficulties. Therefore, exploring the rela...
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Efficient CO and acrolein co-production via paired electrolysis
Paired electrolysis—the combination of a productive cathodic reaction, such as CO2 electroreduction (CO2RR), with selective oxidation on the anode—provides an electrified reaction with maximized atom and energy e...
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Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Open AccessA protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions
Protein ubiquitination regulates a wide range of cellular processes. The degree of protein ubiquitination is determined by the delicate balance between ubiquitin ligase (E3)-mediated ubiquitination and deubiqu...
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Open AccessUnveiling the metabolic landscape of pulmonary hypertension: insights from metabolomics
Pulmonary hypertension (PH) is regarded as cardiovascular disease with an extremely poor prognosis, primarily due to irreversible vascular remodeling. Despite decades of research progress, the absence of defin...