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  1. No Access

    Article

    Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

    Metastasis occurs frequently after resection of pancreatic cancer (PaC). In this study, we hypothesized that multi-parametric analysis of pre-metastatic liver biopsies would classify patients according to thei...

    Linda Bojmar, Constantinos P. Zambirinis, Jonathan M. Hernandez in Nature Medicine (2024)

  2. Article

    Open Access

    Variational AdaBoost knowledge distillation for skin lesion classification in dermatology images

    Knowledge Distillation has shown promising results for classifying skin lesions in dermatology images. Traditional knowledge distillation typically involves the student model passively mimicking the teacher mo...

    **angchun Yu, Guoliang **ong, Jianqing Wu, Jian Zheng in Complex & Intelligent Systems (2024)

  3. Article

    Open Access

    Parallel processing model for low-dose computed tomography image denoising

    Low-dose computed tomography (LDCT) has gained increasing attention owing to its crucial role in reducing radiation exposure in patients. However, LDCT-reconstructed images often suffer from significant noise ...

    Libing Yao, Ji** Wang, Zhongyi Wu in Visual Computing for Industry, Biomedicine… (2024)

  4. No Access

    Article

    Growth Stage-Dependent Variation in Soil Quality and Microbial Diversity of Ancient Gleditsia sinensis

    The environment monitoring of forest is vital for the ecosystem sustainable management, especially soil quality. Ancient Gleditsia sinensis is one of the most distributed ancient trees in Shaanxi. Comprehensive s...

    Sihui Chen, Ge Yu, Fenglai Long, Jian Zheng, Zeyuan Wang in Molecular Biotechnology (2024)

  5. No Access

    Article

    Stepped-up development of accelerator mass spectrometry method for the detection of 60Fe with the HI-13 tandem accelerator

    The Moon provides a unique environment for investigating nearby astrophysical events such as supernovae. Lunar samples retain valuable information from these events, via detectable long-lived “fingerprint” rad...

    Yang Zhang, Sheng-Quan Yan, Ming He, Qing-Zhang Zhao in Nuclear Science and Techniques (2024)

  6. No Access

    Article

    A novel nuclear recoil calibration for liquid helium detectors

    According to many dark matter models, a potential signal registered in a detector would feature a single-scattering nuclear recoil (NR). So, it is crucial to calibrate the detector’s response to NR events. The...

    Fengbo Gu, Jiangfeng Zhou, Junhui Liao, Yuanning Gao in The European Physical Journal Plus (2024)

  7. No Access

    Article

    Binary classification for imbalanced datasets using twin hyperspheres based on conformal method

    Aiming at binary classification of highly imbalanced data, this paper proposes a novel twin-hypersphere method with conformal transformation. To provide favorable environments that the hyperspheres can search ...

    Jian Zheng, Lin Li, Shiyan Wang, Huyong Yan in Cluster Computing (2024)

  8. No Access

    Article

    A fuzzy detection approach to high-dimensional anomalies

    Rare anomalies allow to be hidden in any subspace upon a high-dimensional space so that high-dimensional dimensional of the data brings a lot of trouble for anomalous detectors. To mine high-dimensional anomal...

    Jian Zheng, Nanshan Ruan, **** Wei, Lin Li, **gyue Zhang in Multimedia Systems (2024)

  9. No Access

    Article

    Impact of the subtropical South Pacific on the decadal change in El Niño zonal propagation

    The propagation of sea surface temperature (SST) anomalies along the equatorial Pacific Ocean during El Niño shifted around the late 1970s, previously propagating westward from the eastern Pacific and shifting...

    Jian Zheng, Yuxing Yang, Faming Wang in Climate Dynamics (2024)

  10. Article

    Open Access

    Self-condensation-assisted chemical vapour deposition growth of atomically two-dimensional MOF single-crystals

    Two-dimensional metal-organic frameworks (MOFs) have a wide variety of applications in molecular separation and other emerging technologies, including atomically thin electronics. However, due to the inherent ...

    Lingxin Luo, Lingxiang Hou, Xue** Cui, Pengxin Zhan, ** He in Nature Communications (2024)

  11. Article

    Open Access

    Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) is a significant cancer with limited treatments and a poor prognosis, with the basement membrane (BM) playing a crucial role in its initiation and growth. This study utilized dat...

    Xuyang Liu, Chao Lv, Jian Zheng, **g**g **ao, Nan He, Jun Du in Biochemical Genetics (2024)

  12. Article

    Open Access

    Application direct anterior approach in pediatric femoral head and neck lesions

    Femoral neck is one of the high-risk areas for benign tumors and tumor-like lesions. Small range of lesions may also lead to pathological fracture, femoral head necrosis and other serious problems.

    Jian Zheng, Yanting Zhang, Guoxin Nan in Journal of Orthopaedic Surgery and Research (2024)

  13. Article

    Open Access

    InPACT: a computational method for accurate characterization of intronic polyadenylation from RNA sequencing data

    Alternative polyadenylation can occur in introns, termed intronic polyadenylation (IPA), has been implicated in diverse biological processes and diseases, as it can produce noncoding transcripts or transcripts...

    **aochuan Liu, Hao Chen, Zekun Li, **aoxiao Yang, Wen ** in Nature Communications (2024)

  14. Article

    Open Access

    RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation

    Glioblastoma is one of the most lethal malignant cancers, displaying striking intratumor heterogeneity, with glioblastoma stem cells (GSCs) contributing to tumorigenesis and therapeutic resistance. Pharmacolog...

    Peng Lin, Wenyan Chen, Zhilin Long, Jichuan Yu, Jiayao Yang, Zhen **a in Cell Discovery (2024)

  15. Article

    Author Correction: Spontaneous broken-symmetry insulator and metals in tetralayer rhombohedral graphene

    Kai Liu, Jian Zheng, Yating Sha, Bosai Lyu, Feng** Li in Nature Nanotechnology (2024)

  16. No Access

    Article

    Spontaneous broken-symmetry insulator and metals in tetralayer rhombohedral graphene

    Interactions among charge carriers in graphene can lead to the spontaneous breaking of multiple degeneracies. When increasing the number of graphene layers following rhombohedral stacking, the dominant role of...

    Kai Liu, Jian Zheng, Yating Sha, Bosai Lyu, Feng** Li in Nature Nanotechnology (2024)

  17. No Access

    Article

    Interfacial insight into elevated dielectric properties in graphite nanosheets reinforced PVDF composites via engineering TiO2 shell as an interlayer

    Percolating composites present giant dielectric constant (ε′) at the critical filler loading (fc), whereas the accompanied undesirable high loss and leakage current significantly limit their wide applications owi...

    Chunchao Tu, Fan Zhang, Jian Zheng, Yanqing Zhang in Journal of Polymer Research (2024)

  18. No Access

    Chapter and Conference Paper

    Consensusless Blockchain: A Promising High-Performance Blockchain Without Consensus

    Consensus is unnecessary when the truth is available. In this paper, we present a new perspective of rebuilding the blockchain without consensus. When the consensus phase is eliminated from a blockchain, trans...

    Jian Zheng, Qing Wang, Jianru Lin, Huawei Huang in Blockchain and Trustworthy Systems (2024)

  19. No Access

    Article

    Clinical Application of Computer-Aided Diagnosis System in Breast Ultrasound: A Prospective Multicenter Study

    Ultrasound tends to present very high sensitivity but relatively low specificity and positive predictive value (PPV), which would result in unnecessary breast biopsies. The purpose of this study is to analyze ...

    ** He, Wen Chen, Ming-Yu Bai, Jun Li, Qing-Qing Wang in World Journal of Surgery (2023)

  20. No Access

    Article

    Super-enhancer RNA m6A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinoma

    The biological functions of noncoding RNA N6-methyladenosine (m6A) modification remain poorly understood. In the present study, we depict the landscape of super-enhancer RNA (seRNA) m6A modification in pancreatic...

    Rui Li, Hongzhe Zhao, Xudong Huang, Jialiang Zhang, Ruihong Bai in Nature Genetics (2023)

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