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Open AccessFluorescence resonance energy transfer in atomically precise metal nanoclusters by cocrystallization-induced spatial confinement
Understanding the fluorescence resonance energy transfer (FRET) of metal nanoparticles at the atomic level has long been a challenge due to the lack of accurate systems with definite distance and orientation o...
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Article
Open AccessCamrelizumab-based induction chemoimmunotherapy in locally advanced stage hypopharyngeal carcinoma: phase II clinical trial
This phase II trial aimed to determine the efficacy and safety of induction chemoimmunotherapy of camrelizumab plus modified TPF in locally advanced hypopharyngeal squamous cell carcinoma (LA HSCC) (NCT0415669...
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Article
Open AccessB3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation
B3GNT7, a glycosyltransferase of significant importance that is highly expressed in intestinal epithelial cells, plays a pivotal role in intestinal physiological processes. This study elucidates novel insights...
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Article
Open AccessMXene Sediment-Based Poly(vinyl alcohol)/Sodium Alginate Aerogel Evaporator with Vertically Aligned Channels for Highly Efficient Solar Steam Generation
MXene sediments is innovatively used as photothermal material for seawater desalination.
Inspired by the natural wood transp...
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Open AccessShort-term culture for rapid identification by mass spectrometry and automated antimicrobial susceptibility testing from positive bottles
Early and appropriate antibiotic treatment improves the clinical outcome of patients with sepsis. There is an urgent need for rapid identification (ID) and antimicrobial susceptibility testing (AST) of bacteri...
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Article
Open AccessSingle-cell transcriptomic atlas reveals increased regeneration in diseased human inner ear balance organs
Mammalian inner ear hair cell loss leads to permanent hearing and balance dysfunction. In contrast to the cochlea, vestibular hair cells of the murine utricle have some regenerative capacity. Whether human utr...
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Correction: O-GlcNAcylation of melanophilin enhances radiation resistance in glioblastoma via suppressing TRIM21 mediated ubiquitination
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Article
Evaluating the elderly satisfaction in medical recuperation building in the cold regions of China
Under the influence of aging aggravation, more and more the elderly people spend most of their time in medical buildings. However, there is still a lack of research on the elderly satisfaction with the physica...
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Article
Experiment-free exoskeleton assistance via learning in simulation
Exoskeletons have enormous potential to improve human locomotive performance1–3. However, their development and broad dissemination are limited by the requirement for lengthy human tests and handcrafted control l...
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Article
Study on the Influence of Temporal and Spatial Resolution of Rainfall Data on Watershed Flood Simulation Performance
To investigate the impact of temporal and spatial resolution of rainfall data on watershed flood simulation performance, the rainfall data from meteorological stations and the gridded rainfall data from meteor...
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Article
Graphdiyne coordinated CoMo-MOF formed S-scheme heterojunction boosting photocatalytic hydrogen production
With the development of photocatalytic hydrogen production technology, the effective transport of photogenerated carrier electrons is still one of the main factors affecting the performance of photocatalytic h...
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Heparanase accelerates the angiogenesis and inhibits the ferroptosis of p53-mutant non-small cell cancers in VEGF-dependent manner
The aim of this study is to explore the effects and specific mechanisms of heparanase on angiogenesis and iron deficiency anemia in TP53 mutant cancer. For this purpose, we conducted in vitro cell experiments ...
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Open AccessNonuniform and pathway-specific laminar processing of spatial frequencies in the primary visual cortex of primates
The neocortex comprises six cortical layers that play a crucial role in information processing; however, it remains unclear whether laminar processing is consistent across all regions within a single cortex. I...
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Article
Associations between temporal eating patterns and body composition in young adults: a cross-sectional study
The aim of this study was to examine the associations between body composition and temporal eating patterns, including time of first eating occasion, time of last eating occasion, eating window, and eating jet...
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Article
Open AccessGnRH-driven FTO-mediated RNA m6A modification promotes gonadotropin synthesis and secretion
Gonadotropin precisely controls mammalian reproductive activities. Systematic analysis of the mechanisms by which epigenetic modifications regulate the synthesis and secretion of gonadotropin can be useful for...
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Article
Open AccessAnalytical and Functional Similarity of Aflibercept Biosimilar ABP 938 with Aflibercept Reference Product
ABP 938 is being developed as a biosimilar candidate to aflibercept reference product (RP), a biologic used for certain angiogenic eye disorders. This study was designed to provide a comparative analytical ass...
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Open AccessLateral fenestration of lumbar intervertebral discs in rabbits: development and characterisation of an in vivo preclinical model with multi-modal endpoint analysis
To evaluate the biological and biomechanical effects of fenestration/microdiscectomy in an in vivo rabbit model, and in doing so, create a preclinical animal model of IVDD.
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Article
Polyoxometalates coupled covalent organic frameworks as highly active photothermal nanoreactor for CO2 cycloaddition
Covalent organic frameworks (COFs)-based nanoreactors have attracted broad interest in many fields due to their void-confinement effects. However, the inherent drawback of conventional nanoreactors is the lack...
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Article
Open AccessMolecular tuning boosts asymmetric C-C coupling for CO conversion to acetate
Electrochemical carbon dioxide/carbon monoxide reduction reaction offers a promising route to synthesize fuels and value-added chemicals, unfortunately their activities and selectivities remain unsatisfactory....
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Open AccessAssociation of CCND1 rs9344 polymorphism with lung cancer susceptibility and clinical outcomes: a case-control study
Cyclin D1 (CCND1) plays a pivotal role in cancer susceptibility and the platinum-based chemotherapy response. This study aims to assess the relationship between a common polymorphism (rs9344 G > A) in CCND1 gene ...
