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Open AccessFGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development
Stem/progenitor cells differentiate into different cell lineages during organ development and morphogenesis. Signaling pathway networks and mechanotransduction are important factors to guide the lineage commit...
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Multidimensional vision sensors for information processing
The visual scene in the physical world integrates multidimensional information (spatial, temporal, polarization, spectrum and so on) and typically shows unstructured characteristics. Conventional image sensors...
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Open AccessExploring caspase functions in mouse models
Caspases are enzymes with protease activity. Despite being known for more than three decades, caspase investigation still yields surprising and fascinating information. Initially associated with cell death and...
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Open AccessARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling
ARID1B haploinsufficiency in humans causes Coffin-Siris syndrome, associated with developmental delay, facial dysmorphism, and intellectual disability. The role of ARID1B has been widely studied in neuronal devel...
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Open AccessTwo-dimensional materials for future information technology: status and prospects
Over the past 70 years, the semiconductor industry has undergone transformative changes, largely driven by the miniaturization of devices and the integration of innovative structures and materials. Two-dimensi...
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Open AccessGreen moisture-electric generator based on supramolecular hydrogel with tens of milliamp electricity toward practical applications
Moisture-electric generators (MEGs) has emerged as promising green technology to achieve carbon neutrality in next-generation energy suppliers, especially combined with ecofriendly materials. Hitherto, challen...
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Reconfigurable logic and in-sensor encryption operations in an asymmetrically tunable van der Waals heterostructure
Reconfigurable devices can be used to achieve multiple logic operation and intelligent optical sensing with low power consumption, which is promising candidates for new generation electronic and optoelectronic...
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Controllable van der Waals gaps by water adsorption
Van der Waals (vdW) gaps with ångström-scale heights can confine molecules or ions to an ultimately small scale, providing an alternative way to tune material properties and explore microscopic phenomena. Modu...
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Open AccessOptoelectronic Synapses Based on MXene/Violet Phosphorus van der Waals Heterojunctions for Visual-Olfactory Crossmodal Perception
The photoelectric response of violet phosphorus (VP) is significantly enhanced by the MXene/VP van der Waals heterojunctions and the highest photoresponsivity of VP is demonstr...
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Neuromorphic computing based on halide perovskites
Neuromorphic computing requires electronic systems that can perform massively parallel computational tasks with low energy consumption. Such systems have traditionally been based on complementary metal–oxide–s...
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Computational event-driven vision sensors for in-sensor spiking neural networks
Neuromorphic event-based image sensors capture only the dynamic motion in a scene, which is then transferred to computation units for motion recognition. This approach, however, leads to time latency and can b...
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Optoelectronic graded neurons for bioinspired in-sensor motion perception
Motion processing has proven to be a computational challenge and demands considerable computational resources. Contrast this with the fact that flying insects can agilely perceive real-world motion with their ...
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Open AccessTwo-dimensional semiconducting SnP2Se6 with giant second-harmonic-generation for monolithic on-chip electronic-photonic integration
Two-dimensional (2D) layered semiconductors with nonlinear optical (NLO) properties hold great promise to address the growing demand of multifunction integration in electronic-photonic integrated circuits (EPI...
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An in-memory computing architecture based on a duplex two-dimensional material structure for in situ machine learning
The growing computational demand in artificial intelligence calls for hardware solutions that are capable of in situ machine learning, where both training and inference are performed by edge computation. This ...
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Defect engineering of two-dimensional materials towards next-generation electronics and optoelectronics
The ultrathin body of two-dimensional (2D) materials provides potential for next-generation electronics and optoelectronics. The unavoidable atomic defects substantially determine the physical properties of at...
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Open AccessSensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis
Mesenchymal stem cells (MSCs) reside in microenvironments, referred to as niches, which provide structural support and molecular signals. Sensory nerves are niche components in the homeostasis of tissues such ...
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Open AccessRoom-temperature valley transistors for low-power neuromorphic computing
Valley pseudospin is an electronic degree of freedom that promises highly efficient information processing applications. However, valley-polarized excitons usually have short pico-second lifetimes, which limit...
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Open AccessSpatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis
Cranial neural crest cells are an evolutionary innovation of vertebrates for craniofacial development and function, yet the mechanisms that govern the cell fate decisions of postmigratory cranial neural crest ...
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Silicon photodiodes that multiply
Silicon-based dual-gate photodiodes with electrostatically controlled photocurrents can be used to create imaging systems that can compute incoming visual data.
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Alloy-buffer-controlled van der Waals epitaxial growth of aligned tellurene
Group-VI elemental two-dimensional (2D) materials (e.g., tellurene (Te)) have unique crystalline structures and extraordinarily physical properties. However, it still remains a great challenge to controllably ...