5 Result(s)
within
Steven Stayrook
English
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Article
Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass
An aptamer is combined with a drug to prevent clot formation in a model of cardiopulmonary bypass.
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Article
Crystal structure of the λ repressor and a model for pairwise cooperative operator binding
A crystal structure of the intact, dimeric phage λ cI repressor bound to a DNA operator site reveals an unusual architecture allowing the repressor to adopt a conformation that facilitates cooperative binding ...
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Article
Erratum: Structural basis for the function and inhibition of an influenza virus proton channel
Nature 451, 596–599 (2008) In this Letter, the Protein Data Bank (PDB ID) code for the amantadine complex structure was inadvertently omitted; it should be 3C9J.
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Article
Structural basis for the function and inhibition of an influenza virus proton channel
Until recently, the pH-gated proton channel of influenza A virus, M2, was effectively targeted by amantadine-based antivirals, but resistance to these drugs is now widespread. Two groups now present structural...
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Article
Open AccessPrevalence of the EH1 Groucho interaction motif in the metazoan Fox family of transcriptional regulators
The Fox gene family comprises a large and functionally diverse group of forkhead-related transcriptional regulators, many of which are essential for metazoan embryogenesis and physiology. Defining conserved funct...
