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Protocol
Production of Computationally Designed Small Soluble- and Membrane-Proteins: Cloning, Expression, and Purification
This book chapter focuses on expression and purification of computationally designed small soluble proteins and membrane proteins that are ordinarily difficult to express in good amounts for experiments. Over-...
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Article
Open AccessProtein-directed self-assembly of a fullerene crystal
Learning to engineer self-assembly would enable the precise organization of molecules by design to create matter with tailored properties. Here we demonstrate that proteins can direct the self-assembly of buck...
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Article
Erratum: Structural basis for the function and inhibition of an influenza virus proton channel
Nature 451, 596–599 (2008) In this Letter, the Protein Data Bank (PDB ID) code for the amantadine complex structure was inadvertently omitted; it should be 3C9J.
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Article
Structural basis for the function and inhibition of an influenza virus proton channel
Until recently, the pH-gated proton channel of influenza A virus, M2, was effectively targeted by amantadine-based antivirals, but resistance to these drugs is now widespread. Two groups now present structural...
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Article
Open AccessObservation of glycine zipper and unanticipated occurrence of ambidextrous helices in the crystal structure of a chiral undecapeptide
The de novo design of peptides and proteins has recently surfaced as an approach for investigating protein structure and function. This approach vitally tests our knowledge of protein folding and function, while ...
