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  1. Article

    Open Access

    Tumour cell contamination of autologous stem cells grafts in high-risk neuroblastoma: the good news?

    We analysed the effect of graft-contaminating tumour cells on the long-term survival of 24 patients with high-risk neuroblastoma and found that patients whose grafts contained detectable neuroblastoma cells ha...

    R Handgretinger, W Leung, K Ihm, P Lang, T Klingebiel in British Journal of Cancer (2003)

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    Article

    Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC η with MDR1, MRP and LRP gene expression

    A possible link between protein kinase C (PKC) and P-glycoprotein (P-gp)-mediated-multidrug resistance (MDR) was assumed from studies on MDR cell lines selected in vitro. The functional relevance of PKC for th...

    J Beck, B Bohnet, D Brügger, P Bader, J Dietl, RJ Scheper in British Journal of Cancer (1998)

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    Article

    Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase π gene expression in primary and relapsed state adult and childhood leukaemias

    In a variety of adult and childhood leukaemia cell samples collected at different states of the disease, we analysed in a series of sequentially performed slot-blot or Northern-blot hybridisation experiments t...

    V Gekeler, G Frese, A Noller, R Handgretinger, A Wilisch in British Journal of Cancer (1992)

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    Article

    Funktionen der körpereigenen Abwehr gegen Anaerobier bei Gesunden und Patienten mit chronisch-septischer Granulomatose

    Different strains ofBacteroides fragilis exhibit great differences in sensitivity towards serum from healthy volunteers. In the presence of 10% autologous serum, neutrophilic granulocytes and monocytes (macrophag...

    A. Wildfeuer, R. Dopfer, D. Niethammer, J. Galle, H. Laufen in Klinische Wochenschrift (1987)

  5. Article

    Lung diseases after bone marrow transplantation

    The case histories of 72 subsequently treated patients — 44 with acute leukemia, 10 with chronic myeloid leukemia, 16 with severe aplastic anemia and 2 with neuroblastoma — were analyzed after bone marrow tran...

    H. Link, U. Reinhard, E. Walter, P. Wernet, E. M. Schneider in Klinische Wochenschrift (1986)

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    Article

    Acute folic acid deficiency after bone marrow transplantation

    After bone marrow transplantation (BMT), megaloblastic bone marrow changes are often observed that can only be partially explained by drug effects. Our goal was to find out whether folic acid deficiency repres...

    H. Link, M. Blaurock, P. Wernet, D. Niethammer, K. Wilms in Klinische Wochenschrift (1986)

  7. Article

    Knochenmarktransplantation bei akuter Leukämie, chronisch myeloischer Leukämie, schwerer aplastischer Anämie und Neuroblastom Stadium IV. Einfluß antiviraler Prophylaxe mit Anti-CMV-Hyperimmunglobulin und Azyklovir

    Bone marrow transplantation was performed between IV/82 and X/85 in 64 patients with acute leukemia (n=36), chronic myelogenous leukemia (CML;n=13), severe aplastic anemia (n=12), and neuroblastoma stage IV (n=3)...

    P. Ostendorf, G. Ehninger, R. Dopfer, H. Schmidt, M. Haen in Klinische Wochenschrift (1986)

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    Article

    Bone marrow transplantation for acute leukemia in second or subsequent remission

    Twenty-one patients with acute leukemia in second to fifth remission were treated with bone marrow transplantation: 19 patients with transplants from HLA-matched siblings and two with transplants from identica...

    P. Ostendorf, G. Ehninger, M. -L. Kallmayer, H. Link, K. Schüch in Klinische Wochenschrift (1984)

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    Article

    Knochenmarktransplantation bei Patienten mit Leukämien

    Between October 1979 and March 1982, bone marrow transplantations were performed by the Tübingen Group for BMT on 19 patients with acute leukemia in remission and on one patient with chronic myelocytic leukemi...

    Prof. Dr. K. Wilms, H. Link, P. Meyer, P. Ostendorf, K. Schüch in Klinische Wochenschrift (1982)

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    Article

    Effect of human fibroblast interferon on natural killer cell activity: Stimulation in vitro and inhibition in vivo

    This paper describes the influence of human fibroblast interferon (IFN-β) on the cytotoxic activity of natural killer cells (NK) in vitro and in vivo using the blood of healthy donors and myeloma patients. IFN...

    PD Dr. E. Heidemann, U. Reichmann, K. Wilms, J. Treuner in Klinische Wochenschrift (1982)

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    Article

    Abnormality of erythrocyte membrane protein in a case of congenital stomatocytosis

    Mit einer neuen Methode zur Analyse von Membranproteinen gelang der Nachweis einer Membranproteinanomalie in den Erythrozyten eines Patienten mit congenitaler Stomatozytose; einer chronischen hämolytischen Anä...

    U. Bienzle, S. Bhadki, H. Knüfermann, D. Niethammer in Klinische Wochenschrift (1977)

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    Article

    Impairment of granulocyte function in juvenile diabetes

    Bei 10 Kindern mit Diabetes wurde die Funktion der Granulocyten getestet. Zum Zeitpunkt der Untersuchung waren die Patienten schlecht eingestellt. Fünf Kinder wurden nach Korrektur der Insulindosis und der Diä...

    D. Niethammer, E. Heinze, W. Teller, E. Kleihauer, A. Wildfeuer in Klinische Wochenschrift (1975)

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    Article

    Granulocytendysfunktion

    In the first part we reviewed both the molecular basis of granulocyte function and the inborn defects. The present chapter summarizes our knowledge of the secondary defects of chemotaxis, opsonisation, phagocy...

    D. Niethammer, A. Wildfeuer, E. Kleihauer, O. Haferkamp in Klinische Wochenschrift (1975)

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    Article

    Granulocytendysfunktion

    The insight in the function and dysfunction of granulocytes lately arouses more and more interest. This report summarises our present knowledge. In the first of two chapters the authors review the molecular ba...

    D. Niethammer, A. Wildfeuer, E. Kleihauer, C. Haferkamp in Klinische Wochenschrift (1975)