122 Result(s)
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Article
Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000
Between 1981 and 2000, 6609 children (<18 years of age) were treated in five consecutive trials of the Berlin–Frankfurt–Münster (BFM) study group for childhood acute lymphoblastic leukemia (ALL). Patients were...
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Article
Haematopoietic stem cell transplantation trends in children over the last three decades: a survey by the paediatric diseases working party of the European Group for Blood and Marrow Transplantation
This paper describes the trends in haematopoietic stem cell transplantation (HSCT) activity for children in Europe over the last three decades. We analysed 31 713 consecutive paediatric HSCTs reported by the E...
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Die Schilddrüse nach Stammzelltransplantation im Kindes- und Jugendalter
Die Schilddrüsenfunktionsstörungen vor und nach einer Stammzelltransplantation (SZT) bei Kindern und Jugendlichen wurden untersucht und erfasst.
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Article
Bearbeitung und Transplantation hämatopoetischer Stammzellen
Neue Methoden zur Anreicherung und Depletion definierter Zellpopulationen haben es möglich gemacht, hämatopoetische Stammzellen in hoher Reinheit von gesunden Spendern zu gewinnen.
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Article
Rituximab mediates in vitro antileukemic activity in pediatric patients after allogeneic transplantation
Relapse is a major problem after allogeneic transplantation in children with acute B-lineage lymphoblastic leukemias (ALL) and lymphomas and additional therapeutic strategies are needed to increase graft versus l...
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Comment on ‘CD34+ selected hematopoietic stem cell (HSC) not preceded by any immunosuppressive therapy as effective treatment of graft failure’ – G Milone et al
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Article
Late effects after stem cell transplantation (SCT) in children – growth and hormones
Stem cell transplantation (SCT) has established itself as a very successful therapy in often otherwise unbeatable disorders. In a subset of children and adolescents there are, however, late effects, often as a...
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Survey on haematopoietic stem cell transplantation for children in Europe
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Chapter
Definition und Perspektiven des Faches
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Chapter
Anamnese, Untersuchungstechniken, Umgang mit Patienten und Eltern, psychosoziale Betreuung schwerstkranker und sterbender Kinder
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Article
How and when should we monitor chimerism after allogeneic stem cell transplantation?
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Article
Therapie der häufigsten Pilzvergiftungen
Bei Pilzvergiftungen kurzer Latenz werden Vergiftungen mit vorwiegend gastrointestinaler Wirkung und rein symptomatischer Therapie von Vergiftungen mit zentralnervöser Wirkung unterschieden. Letztere werden in...
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Article
Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective
Children with leukemias and increasing mixed chimerism (increasing MC) after allogeneic stem cell transplantation have the highest risk to relapse. Early immunological intervention was found to be effective in...
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Correction of persistent thrombocytopenia by a boost of CD133+ selected stem cells in a patient transplanted for Wiskott-Aldrich syndrome 10 years ago
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Transplantation of CD34+ enriched allografts in children with nonmalignant diseases: does graft manipulation necessarily result in high incidence of graft failure?
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Clinical relevance of serial quantitative analysis of hematopoietic chimerism after allogeneic stem cell transplantation in children for severe aplastic anemia
Allogeneic stem cell transplantation (allo-SCT) is a well-established treatment modality for children with severe aplastic anemia (SAA). Treatment failures are rare and mostly caused by graft rejection. Increa...
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Article
Transplantation of highly purified peripheral-blood CD34+ progenitor cells from related and unrelated donors in children with nonmalignant diseases
Transplantation of allogeneic stem cells is currently the only curative treatment for some nonmalignant pediatric diseases. We investigated whether transplantation of purified CD34+ stem cells prevents acute and ...
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Successful unrelated allogeneic stem cell transplantation after treatment of lymphoid blast crisis CML with imatinib and imatinib-containing conditioning regimen in a 16-year-old male
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Article
A prospective comparison of immune reconstitution in pediatric recipients of positively selected CD34+ peripheral blood stem cells from unrelated donors vs recipients of unmanipulated bone marrow from related donors
Positively selected CD34+ hematopoietic stem cells from unrelated donors (UD-HSCT) have been successfully transplanted, but little is known about immune reconstitution in this setting. Here we report a prospectiv...
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Article
Meningoenzephalitis und Myokarditis durch seltene Erreger
Wir berichten über einen 12-jährigen Patienten mit Otitis media, passager deutlich eingeschränkter Vigilanz und Herzrhythmusstörungen, die auf eine Infektion durch Mycoplasma pneumoniae zurückzuführen sind. Ig...