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Article
Open AccessSocial distancing and extremely preterm births in the initial COVID-19 pandemic period
Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period.
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Article
Open AccessUse of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study
Extremely preterm (EP) impairment rates are likely underestimated using the Bayley III norm-based thresholds scores and may be better assessed relative to concurrent healthy term reference (TR) infants born in...
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Article
Open AccessNeuroprotective therapies in the NICU in term infants: present and future
Outcomes of neonatal encephalopathy (NE) have improved since the widespread implementation of therapeutic hypothermia (TH) in high-resource settings. While TH for NE in term and near-term infants has proven be...
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Article
Early pum** frequency and coming to volume for mother’s own milk feeding in hospitalized infants
To identify daily pum** frequencies associated with coming to volume (CTV: producing > 500 milliliters of milk per day by postnatal day 14) for mothers of infants in the neonatal intensive care unit (NICU).
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Article
Early brain and abdominal oxygenation in extremely low birth weight infants
Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with po...
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Article
Blanket temperature during therapeutic hypothermia and outcomes in hypoxic ischemic encephalopathy
Determine whether blanket temperatures during therapeutic hypothermia (TH) are associated with 18–22 month outcomes for infants with hypoxic ischemic encephalopathy (HIE).
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Chapter
Pulmonary Hypoplasia
Lungs first develop via epithelial branching and extension into mesenchymal tissue, then by septation and subdivision.
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Article
Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial
This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial.
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Article
Association between neonatal intensive care unit medication safety practices, adverse events, and death
Determine the associations between neonatal intensive care unit (NICU) medication safety practices, laboratory-based adverse events (lab-AEs), and death.
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Article
Correction: Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Blood myo-inositol concentrations in preterm and term infants
To describe relationship between cord blood (representing fetal) myo-inositol concentrations and gestational age (GA) and to determine trends of blood concentrations in enterally and parenterally fed infants from...
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Article
Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants
To test associations between grades 3 or 4 (severe) intraventricular hemorrhage (IVH) and single nucleotide polymorphisms (SNPs) associated with coagulation, inflammation, angiogenesis, and organ development i...
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Article
Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: develo** the future
The next phase of clinical trials in neonatal encephalopathy (NE) focuses on hypothermia adjuvant therapies targeting alternative recovery mechanisms during the process of hypoxic brain injury. Identifying inf...
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Article
Disparities in the use of antenatal corticosteroids among women with hypertension in North Carolina
To evaluate antenatal corticosteroids (ANS) use in pregnant women with hypertension.
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Article
Opioid and benzodiazepine use during therapeutic hypothermia in encephalopathic neonates
To evaluate the use of sedatives and analgesics during therapeutic hypothermia in encephalopathic neonates and assess associations between medication exposure and hospital outcomes.
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Article
Risk of development of treated retinopathy of prematurity in very low birth weight infants
Quantify the risk of treatment for retinopathy of prematurity (ROP) among infants meeting current U.S. screening guidelines.
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Article
Inadequate oral feeding as a barrier to discharge in moderately preterm infants
The objectives describe the frequency that inadequate oral feeding (IOF) is the reason why moderately preterm (MPT) infants remain hospitalized and its association with neonatal morbidities.
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Article
Open AccessDisrupted Maturation of the Microbiota and Metabolome among Extremely Preterm Infants with Postnatal Growth Failure
Growth failure during infancy is a major global problem that has adverse effects on long-term health and neurodevelopment. Preterm infants are disproportionately affected by growth failure and its effects. Her...
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Article
Prolonged duration of early antibiotic therapy in extremely premature infants
Prolonged early antibiotics in extremely premature infants may have negative effects. We aimed to assess prevalence and outcomes of provision of prolonged early antibiotics to extremely premature infants in th...
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Genetic variants associated with patent ductus arteriosus in extremely preterm infants
Patent ductus arteriosus (PDA) is a commonly observed condition in preterm infants. Prior studies have suggested a role for genetics in determining spontaneous ductal closure. Using samples from a large neonat...
