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  1. Article

    Open Access

    Social distancing and extremely preterm births in the initial COVID-19 pandemic period

    Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period.

    Vivek V. Shukla, Benjamin A. Carper, Namasivayam Ambalavanan in Journal of Perinatology (2024)

  2. Article

    Open Access

    Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study

    Extremely preterm (EP) impairment rates are likely underestimated using the Bayley III norm-based thresholds scores and may be better assessed relative to concurrent healthy term reference (TR) infants born in...

    Charles E. Green, Jon E. Tyson, Roy J. Heyne, Susan R. Hintz in Journal of Perinatology (2023)

  3. No Access

    Article

    Relationships between retinopathy of prematurity without ophthalmologic intervention and neurodevelopment and vision at 2 years

    Severe retinopathy of prematurity (ROP) is associated with adverse outcomes. Relationships between milder ROP and outcomes have not been defined. We hypothesized that children with ROP stage ≤3 who did not rec...

    Jane E. Brumbaugh, Edward F. Bell, Shawn C. Hirsch, Emma G. Crenshaw in Pediatric Research (2023)

  4. No Access

    Article

    Cortisol awakening response and developmental outcomes at 6–7 years in children born extremely preterm

    Extremely preterm (EPT) birth has been related to dysregulation of stress responses and behavioral/learning problems at school age. Early adverse experiences can blunt HPA axis reactivity. We hypothesized that...

    Jean Lowe, Janell F. Fuller, Allison G. Dempsey, Barbara Do in Pediatric Research (2023)

  5. No Access

    Article

    Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial

    This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial.

    Ira Adams-Chapman, Kristi L. Watterberg, Tracy L. Nolen in Journal of Perinatology (2021)

  6. No Access

    Article

    Blood myo-inositol concentrations in preterm and term infants

    To describe relationship between cord blood (representing fetal) myo-inositol concentrations and gestational age (GA) and to determine trends of blood concentrations in enterally and parenterally fed infants from...

    Luc P. Brion, Dale L. Phelps, Robert M. Ward, Tracy L. Nolen in Journal of Perinatology (2021)

  7. No Access

    Article

    Neurodevelopmental outcomes at 2 years in term and late preterm newborns enrolled in a trial of hydrocortisone for cardiovascular insufficiency

    Kristi L. Watterberg in Journal of Perinatology (2020)

  8. No Access

    Article

    Neonatal oxygen saturations and blood pressure at school-age in children born extremely preterm: a cohort study

    To explore the relationship between neonatal oxygen saturation and BP at age 6–7 years in a cohort of infants born extremely preterm.

    Marina S. Oren, Vlad Ianus, Betty R. Vohr, Susan R. Hintz in Journal of Perinatology (2020)

  9. No Access

    Article

    Optimizing antenatal corticosteroid therapy for improving outcome of premature infants

    Kristi L. Watterberg, Philip L. Ballard in Pediatric Research (2019)

  10. No Access

    Article

    Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm

    Low birth weight in term-born individuals correlates with adverse cardiometabolic outcomes; excess glucocorticoid exposure has been linked to these relationships. We hypothesized that cortisol and adrenal andr...

    Kristi L. Watterberg, Susan R. Hintz, Barbara Do, Betty R. Vohr in Pediatric Research (2019)

  11. Article

    Neonatal outcomes of moderately preterm infants compared to extremely preterm infants

    Extremely preterm infants (EPT, <29 weeks’ gestation) represent only 0.9% of births in the United States; yet these infants are the focus of most published research. Moderately preterm neonates (MPT, 29–336/7 wee...

    Michele C Walsh, Edward F Bell, Sarah Kandefer, Shampa Saha in Pediatric Research (2017)

  12. Article

    Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants

    Preterm infants with respiratory distress syndrome (RDS) given inositol had reduced bronchopulmonary dysplasia (BPD), death and severe retinopathy of prematurity (ROP). We assessed the safety and pharmacokinet...

    Dale L. Phelps, Robert M. Ward, Rick L. Williams, Tracy L. Nolen in Pediatric Research (2016)

  13. Article

    Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23–29 wk

    Myo-inositol given to preterm infants with respiratory distress has reduced death, increased survival without bronchopulmonary dysplasia, and reduced severe retinopathy of prematurity in two randomized trials. Ph...

    Dale L. Phelps, Robert M. Ward, Rick L. Williams in Pediatric Research (2013)

  14. Article

    Open Access

    Analysis of neonatal clinical trials with twin births

    In neonatal trials of pre-term or low-birth-weight infants, twins may represent 10–20% of the study sample. Mixed-effects models and generalized estimating equations are common approaches for handling correlat...

    Michele L Shaffer, Allen R Kunselman in BMC Medical Research Methodology (2009)

  15. Article

    Open Access

    Joint distribution approaches to simultaneously quantifying benefit and risk

    The benefit-risk ratio has been proposed to measure the tradeoff between benefits and risks of two therapies for a single binary measure of efficacy and a single adverse event. The ratio is calculated from the...

    Michele L Shaffer, Kristi L Watterberg in BMC Medical Research Methodology (2006)

  16. Article

    Adrenal Insufficiency and Cardiac Dysfunction in the Preterm Infant

    Kristi L Watterberg in Pediatric Research (2002)

  17. Article

    Impaired Glucocorticoid Synthesis in Premature Infants Develo** Chronic Lung Disease

    Premature infants have higher cortisol precursor concentrations than term infants; however, many sick preterm infants have surprisingly low cortisol concentrations. Those who develop chronic lung disease (CLD)...

    Kristi L Watterberg, Jeffrey S Gerdes, Kristen L Cook in Pediatric Research (2001)

  18. Article

    Lower Cortisol Concentrations in Premature Infants with Patent Ductus Arteriosus (PDA)

    Kristi L Watterberg, Susan M Scott, Conra Backstrom in Pediatric Research (1999)

  19. Article

    Prophylaxis against Early Adrenal Insufficiency to Prevent Chronic Lung Disease in Premature Infants

    Kristi L Watterberg, Jeffrey S Gerdes, Kathleen L Gifford in Pediatric Research (1999)

  20. Article

    Impaired Glucocorticoid Synthesis in Preterm Infants Who Develop Chronic Lung Disease (CLD)

    Kristi L Watterberg, Jeffrey S Gerdes, Kristen L Cook in Pediatric Research (1999)

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