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  1. Article

    Open Access

    Prescribing practices of inhaled corticosteroids for premature infants in the neonatal intensive care unit

    Despite limited safety and efficacy data, inhaled corticosteroids (ICS) are prescribed to premature infants in the neonatal intensive care unit (NICU). We examined contemporary use and risk factors for ICS use...

    Monica Tang, Anna Ibrahim, Christopher Laughon, Kaila Moore in Journal of Perinatology (2024)

  2. No Access

    Article

    Association of maternal pre-pregnancy or first trimester body mass index with neurodevelopmental impairment or death in extremely low gestational age neonates

    To compare the rates of death or survival with severe neurodevelopmental impairment (sNDI) at 2 years among extremely preterm infants in relation to pre-pregnancy or first-trimester maternal body mass index (B...

    Sanjay Chawla, Abbot R. Laptook, Emily A. Smith, Sylvia Tan in Journal of Perinatology (2024)

  3. No Access

    Article

    A phase I trial of caffeine to evaluate safety in infants with hypoxic-ischemic encephalopathy

    Caffeine provides neuroprotection following hypoxic-ischemic injury in animals. We characterized the safety of escalating doses of caffeine in infants with hypoxic-ischemic encephalopathy (HIE) receiving thera...

    Wesley Jackson, Daniel Gonzalez, Rachel G. Greenberg in Journal of Perinatology (2024)

  4. No Access

    Article

    Morbidity and mortality of twins and triplets compared to singleton infants delivered between 26–34 weeks gestation in the United States

    To describe in-hospital morbidities and mortality among twins and triplets delivered at ≥26 to ≤34 weeks gestational age (GA) while controlling for prematurity and growth restriction.

    Sara Khan, Ryan Kilpatrick, Daniel K. Benjamin, Sarah E. Kolnik in Journal of Perinatology (2024)

  5. No Access

    Article

    Trends in COVID-19 diagnoses and outcomes in infants hospitalized in the neonatal intensive care unit

    Characterize the prevalence of coronavirus disease 2019 (COVID-19) diagnosis among mothers with infants hospitalized in 294 neonatal intensive care units (NICUs), and demographics and outcomes of infants with ...

    Elizabeth B. Heyward, Reese H. Clark, P. Brian Smith in Journal of Perinatology (2024)

  6. No Access

    Article

    Risk factors and epidemiology of spontaneous intestinal perforation among infants born at 22–24 weeks’ gestational age

    To describe the epidemiology, risk factors, and timing of spontaneous intestinal perforation (SIP) among infants born at 22–24 weeks’ gestational age (GA).

    Pavan V. Thakkar, Kent F. Sutton, Chloe-Ann B. Detwiler in Journal of Perinatology (2024)

  7. No Access

    Article

    Underimmunization of very low birth weight infants at discharge from the neonatal intensive care unit

    To quantify immunization status among premature infants discharged from neonatal intensive care units (NICUs), and identify risk factors for underimmunization.

    Veronica Quiett, Elizabeth Thompson, Sudha R. Raman in Journal of Perinatology (2024)

  8. No Access

    Article

    Trends in morbidities of late preterm infants in the neonatal intensive care unit

    To characterize demographics and trends in length of stay (LOS), morbidities, and mortality in late preterm infants.

    Chelsea Lockyear, Kristi Coe, Rachel G. Greenberg in Journal of Perinatology (2023)

  9. No Access

    Article

    Use of vasopressors for septic shock in the neonatal intensive care unit

    To describe outcomes for infants in the neonatal intensive care unit with septic shock based on the vasopressor administered.

    Henry P. Foote, Daniel K. Benjamin, Rachel G. Greenberg in Journal of Perinatology (2023)

  10. No Access

    Article

    Early antibiotic exposure in very-low birth weight infants and infection risk at 3–7 days after birth

    To determine rates of late-onset infection (LOI) during postnatal days 3–7 among preterm infants, based on antibiotic exposure during days 0–2.

    Sarah A. Coggins, Zachary Willis, Daniel K. Benjamin in Journal of Perinatology (2023)

  11. Article

    Open Access

    Endotoxin content in neonatal formulas, fortification, and lactoferrin products: association with outcomes and guidance on acceptable limits

    While endotoxin (lipopolysaccharide) can be harmful and contribute to morbidity and mortality with Gram-negative sepsis or necrotizing enterocolitis in preterm infants, non-toxic amounts are produced as part o...

    David A. Kaufman, Patti H. Perks, Rachel G. Greenberg, David Jensen in BioMetals (2023)

  12. No Access

    Article

    Congenital anomalies of the kidney and urinary tract (CAKUT) in critically ill infants: a multicenter cohort study

    The aim of the study was to determine the prevalence of congenital anomalies of the kidney and urinary tract (CAKUT) in the neonatal intensive care unit (NICU) and to evaluate risk factors associated with wors...

    Esther Huimin Leow, Jan Hau Lee, Christoph P. Hornik, Yong Hong Ng in Pediatric Nephrology (2023)

  13. No Access

    Article

    Evaluation and validation of a prediction model for extubation success in very preterm infants

    To perform an external validation of a publicly available model predicting extubation success in very preterm infants.

    Rebecca A. Dryer, Anand Salem, Vivek Saroha, Rachel G. Greenberg in Journal of Perinatology (2022)

  14. Article

    Open Access

    Eating, Slee**, Consoling for Neonatal Opioid Withdrawal (ESC-NOW): a Function-Based Assessment and Management Approach study protocol for a multi-center, stepped-wedge randomized controlled trial

    Leslie W. Young, Songthip Ounpraseuth, Stephanie L. Merhar, Alan E. Simon in Trials (2022)

  15. No Access

    Article

    Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship

    Define optimal ampicillin dosing for empiric early-onset sepsis (EOS) therapy in preterm neonates.

    Jennifer Le, Rachel G. Greenberg, YoungJun Yoo, Reese H. Clark in Journal of Perinatology (2022)

  16. No Access

    Article

    Association between postmenstrual age and furosemide dosing practices in very preterm infants

    Furosemide renal clearance is slow after very preterm (VP) birth and increases with postnatal maturation. We compared furosemide dose frequency and total daily dose between postmenstrual age (PMA) groups in VP...

    Nicolas A. Bamat, Elizabeth J. Thompson, Rachel G. Greenberg in Journal of Perinatology (2022)

  17. No Access

    Article

    Population Pharmacokinetics of Moxifloxacin in Children

    Moxifloxacin is a fluoroquinolone that is commonly used in adults, but not children. Certain clinical situations compel pediatric clinicians to use moxifloxacin, despite its potential for toxicity and limited ...

    Rachel G. Greenberg, Cornelia B. Landersdorfer, Nazario Rivera-Chaparro in Pediatric Drugs (2022)

  18. No Access

    Article

    Physiologically Based Pharmacokinetic Modeling of Meropenem in Preterm and Term Infants

    Meropenem is a broad-spectrum carbapenem antibiotic approved by the US Food and Drug Administration for use in pediatric patients, including treating complicated intra-abdominal infections in infants < 3 month...

    Samit Ganguly, Andrea N. Edginton, Jacqueline G. Gerhart in Clinical Pharmacokinetics (2021)

  19. Article

    Comparative efficacy and safety of late surfactant preparations: a retrospective study

    Characterize the use, efficacy, and safety of poractant alfa and calfactant surfactants compared to beractant in preterm infants receiving late surfactant.

    Morgan D. Lane, Sujata Kishnani, Obianuju Udemadu in Journal of Perinatology (2021)

  20. No Access

    Article

    Covariation of changing patent ductus arteriosus management and preterm infant outcomes in Pediatrix neonatal intensive care units

    To test the hypothesis that NICU-specific preterm infant outcomes co-vary with changes in local patent ductus arteriosus (PDA) management.

    James I. Hagadorn, Michele L. Shaffer, Veeral N. Tolia in Journal of Perinatology (2021)

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