26 Result(s)

Article

Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants

Preterm infants with respiratory distress syndrome (RDS) given inositol had reduced bronchopulmonary dysplasia (BPD), death and severe retinopathy of prematurity (ROP). We assessed the safety and pharmacokinet...

Dale L. Phelps, Robert M. Ward, Rick L. Williams, Tracy L. Nolen… in Pediatric Research (2016)

Article

Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23–29 wk

Myo-inositol given to preterm infants with respiratory distress has reduced death, increased survival without bronchopulmonary dysplasia, and reduced severe retinopathy of prematurity in two randomized trials. Ph...

Dale L. Phelps, Robert M. Ward, Rick L. Williams… in Pediatric Research (2013)

Article

The effects of aggressive vs. conservative phototherapy on the brainstem auditory evoked responses of extremely-low-birth-weight infants

This study was a two-center, stratified, parallel-group randomized trial comparing the effects of aggressive vs. conservative phototherapy on brainstem auditory evoked response (BAER) latencies in infants with...

Robert E. Lasky, Michael W. Church, Mark S. Orlando, Brenda H. Morris… in Pediatric Research (2012)

Article

Urinary Vascular Endothelial Growth Factor (VEGF) in Retinopathy of Prematurity and Other Proliferative Retinopathies

Carl T D'Angio, Jayakrishna Ambati, Dale L Phelps in Pediatric Research (1999)

Article

Retinopathy of Prematurity (ROP)--Active and Post Cryotherapy in Human Infants: Spatial Expression of Retinal Vascular Endothelial Growth Factor (VEGF) mRNA † 296

Dale L Phelps, William M Maniscalco, Leon Metlay, Richard H Watkins… in Pediatric Research (1998)

Article

Early intravenous dexamethasone (dex) for the prevention of BPD in surfactant treated babies with RDS. 1138

Robert A Sinkin, Harry S Dweck, Michael J Horgan, Keith J Gallaher… in Pediatric Research (1998)

Article

School Age Neurodevelopmental Outcome in Surfactant-Treated Premature Infants With and Without Chronic Lung Disease † 1584

Rita M Ryan, Gary J Myers, James A Kendig, Christopher Cox… in Pediatric Research (1997)

Article

CHARACTERISTICS OF INFANTS WITH THREE PATTERNS OF NEONATAL CHRONIC LUNG DISEASE: A PRELIMINARY STUDY. † 1187

Lama Charafeddine, Carl T D'Angio, Dale L Phelps in Pediatric Research (1996)

Article

Two Doses of Early Intravenous Dexamethasone for the Prevention of Bronchopulmonary Dysplasia in Babies with Respiratory Distress Syndrome

ABSTRACT: Bronchopulmonary dysplasia is an important complication of ventilation in babies for which treatment with steroids has been advocated. We report the results of a phase I study of early i.v. dexametha...

Raymond J Sanders, Christopher Cox, Dale L Phelps, Robert A Sinkin in Pediatric Research (1994)

Article

Oxygen-Induced Retinopathy: Lack of Adverse Heparin Effect

ABSTRACT: Retinopathy of prematurity is a disorder of abnormal retinal vascular proliferation, and one hypothesis for its pathogenesis involves abnormal activity of angiogenic growth factors in the retina. One...

Rosemary D Higgins, Dale L Phelps in Pediatric Research (1990)

Article

Reduced Severity of Oxygen-Induced Retinopathy in Kittens Recovered in 28% Oxygen

ABSTRACT: Chronic hypoxemia adversely affects the retinopathy observed in kittens after a hyperoxic exposure (80% oxygen) in the 1st wk of life. To test the converse hypothesis, 55 kittens were randomly assign...

Dale L Phelps in Pediatric Research (1988)

Article

300 LACK OF DRUG EFFECT ON OXYGEN INDUCED RETINAL ARTERY CONSTRICTION IN THE KITTEN

The initial injury in the animal model of oxygen induced retinopathy is thought to be irreversible arteriolar constriction. Since vitamin E is beneficial in this model, its effect on early arteriolar constrict...

Dale L Phelps in Pediatric Research (1985)

Article

1481 EFFECT OF IV TOCOPHEROL (VIT E) ON RETINOPATHY OF PREMATURITY (ROP)

287 infants were enrolled in a double masked, randomized controlled trial of vitamin E (E) v placebo (P) given from day 1 until the retinal vessels reached the ora serrata. Initial IV doses were changed to ora...

Dale L Phelps, Arthur Rosenbaum, Sherwin J Isenberg, Rosemary D Leake… in Pediatric Research (1985)

Article

SAFETY OF INTRAVASCULAR TOCOPHEROL IN A RANDOMIZED DOUBLE BLIND TRIAL IN PREMATURE INFANTS

We prospectively studied the potential side effects of parenteral vitamin E or tocopherol (T) while testing its effectiveness in preventing Retinopathy of Prematurity (ROP).

Dale L Phelps, Arthur Rosenbaum, Rosemary D Leake, Sherwin Isenberg… in Pediatric Research (1984)

Article

Survival of Oral Human Immune Serum Globulin in the Gastrointestinal Tract of Low Birth Weight Infants

Summary: Six immature infants were given oral feedings of 10% preservative-free human immune serum globulin ranging from 1 to 8 ml/kg/day. A seventh infant served as a control. Undigested and partially digeste...

Paul M Blum, Dale L Phelps, Bonnie J Ank, Herbert J Krantman… in Pediatric Research (1981)

Article

1576 RELATIONSHIPS BETWEEN FETAL HEART RATE MONITORING(FHR) AND CREATINE PHOSPHOKINASE-BB (CK-BB)

Significant elevations in CK-BB (>20) correlate well with moderate degrees of perinatal asphyxia and are particularly valuable in assessing the degree of associated brain damage. FHR has been utilized in the o...

Rochelle C Feldnan, W Donald Shields, Khalil M A Tabsh, Dale L Phelps in Pediatric Research (1981)