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Association of maternal pre-pregnancy or first trimester body mass index with neurodevelopmental impairment or death in extremely low gestational age neonates
To compare the rates of death or survival with severe neurodevelopmental impairment (sNDI) at 2 years among extremely preterm infants in relation to pre-pregnancy or first-trimester maternal body mass index (B...
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Open AccessUse of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study
Extremely preterm (EP) impairment rates are likely underestimated using the Bayley III norm-based thresholds scores and may be better assessed relative to concurrent healthy term reference (TR) infants born in...
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Article
Relationships between retinopathy of prematurity without ophthalmologic intervention and neurodevelopment and vision at 2 years
Severe retinopathy of prematurity (ROP) is associated with adverse outcomes. Relationships between milder ROP and outcomes have not been defined. We hypothesized that children with ROP stage ≤3 who did not rec...
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Article
Cortisol awakening response and developmental outcomes at 6–7 years in children born extremely preterm
Extremely preterm (EPT) birth has been related to dysregulation of stress responses and behavioral/learning problems at school age. Early adverse experiences can blunt HPA axis reactivity. We hypothesized that...
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Article
Early brain and abdominal oxygenation in extremely low birth weight infants
Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with po...
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Article
DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function
There is increased risk of cardiovascular, metabolic, and hypertensive disorders in later life in the preterm population. We studied school-age children who had been born extremely premature who had undergone ...
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Article
The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants
Determine how neurodevelopmental impairment (NDI) relates to concurrent outcomes for children born extremely preterm.
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Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial
This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial.
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Article
Postpartum depression in mothers with pregnancies complicated by fetal cardiac anomaly
To investigate factors associated with positive postpartum depression (PPD) screen in pregnancies complicated by fetal congenital cardiac anomaly.
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Article
Factors associated with follow-up of infants with hypoxic–ischemic encephalopathy in a high-risk infant clinic in California
To determine the rates of high-risk infant follow-up (HRIF) attendance and the characteristics associated with follow-up among infants with hypoxic–ischemic encephalopathy (HIE) in California.
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Article
Timing of Transfer and Mortality in Neonates with Hypoplastic Left Heart Syndrome in California
Maternal race/ethnicity is associated with mortality in neonates with hypoplastic left heart syndrome (HLHS). We investigated whether maternal race/ethnicity and other sociodemographic factors affect timing of...
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Article
Neonatal oxygen saturations and blood pressure at school-age in children born extremely preterm: a cohort study
To explore the relationship between neonatal oxygen saturation and BP at age 6–7 years in a cohort of infants born extremely preterm.
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Survival of infants with congenital diaphragmatic hernia in California: impact of hospital, clinical, and sociodemographic factors
To understand factors associated with care and survival among babies with congenital diaphragmatic hernia (CDH).
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Article
Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm
Low birth weight in term-born individuals correlates with adverse cardiometabolic outcomes; excess glucocorticoid exposure has been linked to these relationships. We hypothesized that cortisol and adrenal andr...
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Article
Prenatally diagnosed omphalocele: characteristics associated with adverse neonatal outcomes
To characterize factors associated with adverse neonatal outcomes in prenatally diagnosed omphalocele cases.
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Article
Differences in patient characteristics and care practices between two trials of therapeutic hypothermia
The Induced Hypothermia (IH) and Optimizing Cooling (OC) trials for hypoxic–ischemic encephalopathy (HIE) had similar inclusion criteria. The rate of death/moderate–severe disability differed for the subgroups...
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Article
Neuroimaging and Bayley-III correlates of early hand function in extremely preterm children
Investigate associations between 18 and 22-month corrected age hand function, adverse findings on serial cranial ultrasound (CUS) and near-term brain MRI (ntMRI), and Bayley-III scores in extremely preterm (EP...
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Article
Utility of prenatal MRI in the evaluation and management of fetal ventriculomegaly
Fetal ventriculomegaly may occur in isolation or as part of a broader syndrome. We aimed to determine the added value of magnetic resonance imaging (MRI) for informing the pre-natal and postnatal care of pregn...
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Article
Association between sedation–analgesia and neurodevelopment outcomes in neonatal hypoxic-ischemic encephalopathy
To evaluate the association between sedation–analgesia (SA) during initial 72 h and death/disability at 18 months of age in neonatal hypoxic-ischemic encephalopathy (HIE).
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Article
Predictors of poor neonatal outcomes in prenatally diagnosed multicystic dysplastic kidney disease
Multicystic dysplastic kidney (MCDK) is one of the most common anomalies detected by prenatal ultrasound. Our objective was to identify factors associated with severe adverse neonatal outcomes of prenatally di...