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Synergistically Augmenting Cancer Immunotherapy by Physical Manipulation of Pyroptosis Induction
Pyroptosis is a newly recognized type of programmed cell death mediated by the gasdermin family and caspase. It is characterized by the formation of...
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Synergistic effects of thermosensitive liposomal doxorubicin, mild hyperthermia, and radiotherapy in breast cancer management: an orthotopic mouse model study
Liposome formulations of the cancer drug doxorubicin have been developed to address the severe side effects that result from administration of this...
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A Hypoxia-Sensitive Drug Delivery System Constructed by Nitroimidazole and its Application in the Treatment of Hepatocellular Carcinoma
Hypoxia is an important pathological phenomenon, and it can induce many tumor microenvironment changes, such as accumulations of intracellular lactic...
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A retrospective cohort study: is COVID-19 BNT162b2 mRNA vaccination a trigger factor for cluster headache?
ObjectıveCluster headache (CH) is a coronavirus 2019 (COVID-19) vaccination-related adverse event. There are a few case reports of relapses or de...
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The Neuro-cardiac Axis in Arrhythmogenesis: Role and Impact of Autonomic Modulation
The autonomic nervous system consisting of two limbs, the sympathetic and parasympathetic nervous system, plays a key role in the modulation of...
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Clinical Presentation and Therapy of Arrhythmias
The electrocardiogram (ECG) is one of the cornerstones of diagnostic investigations in pediatric or adult cardiology. The standard ECG includes 12...
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Nanoparticles for Neural Applications
Nanotechnology represents a novel powerful technology with the potential to overcome some of the problems related to brain research. In particular,...
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Emerging Advances in Nanocarriers Approaches in the Effective Therapy of Pain Related Disorders: Recent Evidence and Futuristic Needs
Pain disorders are the primary cause of disability nowadays. These disorders, such as rheumatoid arthritis (RA) and osteoarthritis (OA), cause loss...
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Harnessing immunotherapy to enhance the systemic anti-tumor effects of thermosensitive liposomes
Chemotherapy plays an important role in debulking tumors in advance of surgery and/or radiotherapy, tackling residual disease, and treating...
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Introduction to Acute, Chronic, and Episodic Pain
Pain places an enormous burden on the healthcare system as well as the quality of life of individuals all around the world. With regard to the...
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Lipid-based nanoparticles for photosensitive drug delivery systems
BackgroundNumerous drug delivery strategies have been studied, but many hurdles exist in drug delivery rates to the target site. Recently,...
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Integrated proteogenomic characterization reveals an imbalanced hepatocellular carcinoma microenvironment after incomplete radiofrequency ablation
BackgroundEfforts to precisely assess tumor-specific T-cell immune responses still face major challenges, and the potential molecular mechanisms...
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Chemokines and Chemokine Receptors in Cancer: An Update
The chemokine family is composed of small chemotactic cytokines and receptors that mediate the infiltration of various immune cells. According to the...
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Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy
This chapter provides an overview of the prospects of using electromagnetic fields (EMFs), with a specific focus on static magnetic fields, for...
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Therapeutic Peptide Delivery: Fundamentals, Formulations, and Recent Advances
Recent advances in the field of peptide therapeutics have led to the design and synthesis of many promising peptides. However, research and...
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Gold Nanoclusters as Emerging Theranostic Interventions for Biomedical Applications
Photoluminescent gold nanoclusters (AuNCs) are an emerging class of nanotheranostic agents for biomedical applications due to their unique...
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Emerging Polymer-Based Nanomaterials for Cancer Therapeutics
Cancer is a highly complex disease and a global health challenge with tumour heterogeneity and therapy resistance posing major hurdles in its...
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Cellular based immunotherapy for primary liver cancer
Primary liver cancer (PLC) is a common malignancy with high morbidity and mortality. Poor prognosis and easy recurrence on PLC patients calls for...
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Unveiling the Therapeutic Potential: Metabolomics Insights into Medicinal Plants and Their Antidiabetic Effects
Purpose of ReviewThis review compiles diverse plant materials and their phytoconstituents, exploring their potential as antidiabetic agents. It aims...
