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Open AccessAuthor Correction: Global proteomic identifies multiple cancer-related signaling pathways altered by a gut pathobiont associated with colorectal cancer
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Open AccessGlobal proteomic identifies multiple cancer-related signaling pathways altered by a gut pathobiont associated with colorectal cancer
In this work, we investigated the oncogenic role of Streptococcus gallolyticus subsp. gallolyticus (SGG), a gut bacterium associated with colorectal cancer (CRC). We showed that SGG UCN34 accelerates colon tumor ...
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Article
Open AccessThe plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci
Streptococcus agalactiae (Group B Streptococcus or GBS) is a frequent cause of serious disease in newborns and adults. Epidemiological evidence indicates a strong association between GBS strains belonging to the ...
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Open AccessA mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
Group B streptococcal (GBS) meningitis remains a devastating disease. The absence of an animal model reproducing the natural infectious process has limited our understanding of the disease and, consequently, d...
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Open AccessEnvironmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials
The bacterial pathway for fatty acid biosynthesis, FASII, is a target for development of new anti-staphylococcal drugs. This strategy is based on previous reports indicating that self-synthesized fatty acids a...
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Open AccessSingle nucleotide resolution RNA-seq uncovers new regulatory mechanisms in the opportunistic pathogen Streptococcus agalactiae
Streptococcus agalactiae, or Group B Streptococcus, is a leading cause of neonatal infections and an increasing cause of infections in adults with underlying diseases. In an effort to reconstru...
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Open AccessMultiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci
Cell-wall peptidoglycan (PG) of Gram-positive bacteria is a strong and elastic multi-layer designed to resist turgor pressure and determine the cell shape and growth. Despite its crucial role, its architecture...
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Correction: Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Nature Communications 5: Article number:4544 (2014); Published 4 Aug 2014; Updated 28 Jan 2015 The original version of this Article contained an error in the spelling of a member of the DEVANI Consortium, Luci...
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Open AccessStreptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and North Amer...
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Brinster et al. reply
Replying to: W. Balemans et al. Nature 462, 10.1038/nature08667 (2009)
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Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens
The type II fatty acid synthesis (FASII) pathway has been suggested to be a promising antimicrobial target, and the antibiotics platensimycin and platencin that target this pathway are claimed to be potentiall...
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Roles of Environmental Heme, and Menaquinone, in Streptococcus Agalactiae
Most bacteria require iron for growth. However, as it may not be directly available under aerobic conditions, bacteria may use iron-sequestering molecules, such as bacterially encoded siderophores, or heme, wh...
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Summary of the Round Table Discussion on Genome Structure and Regulation of Gene Expression in Streptococci and Enterococci
The significant progress made in recent years in the areas of streptoccocal genome structure and function was highlighted by the following topical contributions
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Nucleotide sequence of the kanamycin resistance determinant of the pneumococcal transposon Tn1545: Evolutionary relationships and transcriptional analysis of aphA-3 genes
The nucleotide sequence of the kanamycin resistance determinant aphA-3 encoded by transposon Tn1545 from Streptococcus pneumoniae was determined and compared to those of plasmids pJH1 and pIP1433 from Streptococc...
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DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and Bacillus subtilis
The gene conferring resistance to kanamycin, aphA, and originating from the streptococcal plasmid pJH1 was inserted into a shuttle vector. Full expression of aphA was obtained in Escherichia coli and Bacillus sub...
