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  1. Article

    Open Access

    Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials

    The bacterial pathway for fatty acid biosynthesis, FASII, is a target for development of new anti-staphylococcal drugs. This strategy is based on previous reports indicating that self-synthesized fatty acids a...

    Claire Morvan, David Halpern, Gérald Kénanian, Constantin Hays… in Nature Communications (2016)

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  2. Article

    Brinster et al. reply

    Replying to: W. Balemans et al. Nature 462, 10.1038/nature08667 (2009)

    Sophie Brinster, Gilles Lamberet, Bart Staels, Patrick Trieu-Cuot… in Nature (2010)

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  3. No Access

    Article

    Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

    The type II fatty acid synthesis (FASII) pathway has been suggested to be a promising antimicrobial target, and the antibiotics platensimycin and platencin that target this pathway are claimed to be potentiall...

    Sophie Brinster, Gilles Lamberet, Bart Staels, Patrick Trieu-Cuot… in Nature (2009)