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Article
Open AccessThe plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci
Streptococcus agalactiae (Group B Streptococcus or GBS) is a frequent cause of serious disease in newborns and adults. Epidemiological evidence indicates a strong association between GBS strains belonging to the ...
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Article
Open AccessA mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
Group B streptococcal (GBS) meningitis remains a devastating disease. The absence of an animal model reproducing the natural infectious process has limited our understanding of the disease and, consequently, d...
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Protocol
Modular Gene Over-expression Strategies for Candida albicans
Over-expression is a valid functional genomics approach to characterise genes of unknown function on a genome-wide scale. Strains are engineered to over-express a specific gene and the resulting gain-of-functi...
