22 Result(s)

Article

Effects of topoisomerase 2 inhibitors on the MLL gene in children receiving chemotherapy: a prospective study

The molecular effects of etoposide in haemopoietic cells suggest that mixed lineage leukaemia (MLL) abnormalities can be biomarkers of patient susceptibility to the genotoxic effects of topoisomerase 2 (topo 2) i...

A Ng, G M Taylor, R F Wynn, O B Eden in Leukemia (2005)

Article

Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop

The Sixth International Childhood ALL Workshop was made possible by unrestricted educational grants from Sanofi-Synethelabo Inc., Glaxosmithkline, Enzon Inc., and Ilex. Preparation of the Meeting Report was su...

C-H Pui, M Schrappe, G Masera, J Nachman, H Gadner, O B Eden, W E Evans… in Leukemia (2004)

Article

Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements

To assess the clinical heterogeneity among patients with acute lymphoblastic leukemia (ALL) and various 11q23 abnormalities, we analyzed data on 497 infants, children and young adults treated between 1983 and ...

C-H Pui, J M Chessells, B Camitta, A Baruchel, A Biondi, J M Boyett, A Carroll… in Leukemia (2003)

Article

Pseudosarcoma of the bladder associated with residual urachus in a 3-year-old girl

Bladder pseudosarcoma or pseudosarcomatous myofibroblastic proliferation (PMP) is a rare but nevertheless very important differential diagnosis of any bladder mass. In childhood most such masses are usually m...

S. Meyer, J. Bruce, A. Kelsey, O. B. Eden in Pediatric Surgery International (2000)

Article

A Comparison of Cox Regression and Neural Networks for Risk Stratification in Cases of Acute Lymphoblastic Leukaemia in Children

For most diseases there is considerable interest in the problem of classification, both in relation to medical diagnosis and for prognosis. Multivariate statistical methods are conventionally used as an aid to...

D. J. Groves, S. W. Smye, S. E. Kinsey, S. M. Richards… in Neural Computing & Applications (1999)

Article

Recommendations on the use of colony-stimulating factors in children: conclusions of a European panel

During 1996 and 1997 a panel of European haematologists, oncologists, and neonatologists developed specific paediatric guidelines for the use of colony stimulating factors based on published literature and th...

G. Schaison, O. B. Eden, G. Henze, W. A. Kamps… in European Journal of Pediatrics (1998)

Article

Central venous catheter tip position and malfunction in a paediatric oncology unit

An audit of 151 central venous catheters (CVCs) in 118 children with malignant disease was carried out over 20 months. The types included 31 valved silastic (Groshong), 58 non-valved silastic (Hickman), and 62...

H. Lucas, S. P. Attard-Montalto, V. Saha, A. Bristow… in Pediatric Surgery International (1996)

Article

Voodoo, videos and fits: Another presentation of truancy

O. B. Eden, A. W. McNinch in European Journal of Pediatrics (1992)

Article

Hyperviscosity in HIV infected children — a potential hazard during intravenous immunoglobulin therapy

A four year old boy with symptoms of HIV infection and serum IgG of 53.2 g/l had been treated for 16 months with regular infusions of intravenous immunoglobulin (IV IgG). During one such infusion he developed ...

R. A. Hague, O. B. Eden, P. L. Yap, J. Y. Q. Mok, P. Rae in Blut (1990)

Article

Chylous effusion: a rare presentation of childhood malignancy

Two boys, aged 5 and 4 years, recently presented with gross chylous ascites and chylothorax respectively. In both cases the underlying pathology was found to be rhabdomyosarcoma.

M. E. Chapman, O. B. Eden, J. E. Burns, G. A. MacKinlay… in Pediatric Surgery International (1988)

Chapter and Conference Paper

Medical Research Council Childhood Leukaemia Trial VIII Compared with Trials II–VII: Lessons for Future Management

Over the last 15 years, the Working Party on Childhood Leukaemia of the Medical Research Council (MRC) has conducted a series of therapeutic trials on acute lymphoblastic leukaemia (ALL). The broad principles,...

O. B. Eden, J. Lilleyman, M. P. Shaw, S. Richards, J. Peto in Acute Leukemias (1987)

Article

A phase II study of ifosfamide in children with recurrent solid tumours

Twenty children with recurrent or unresponsive tumours (10 Wilms', 3 rhabdomyosarcoma, 4 Ewings's, 1 osteosarcoma, 1 hepatoblastoma, 1 hepatoma) and one untreated patient with renal carcinoma were given ifosfa...

C. R. Pinkerton, H. Rogers, C. James, A. Bowman… in Cancer Chemotherapy and Pharmacology (1985)

Article

Adjuvant low dose radiation in childhood non-Hodgkin's lymphoma (report from the United Kingdom Childrens' Cancer Study Group--UKCCSG)

From July 1977 to July 1983, 120 children with non-Hodgkin's Lymphoma entered a randomised trial of combination chemotherapy and radiotherapy. The primary site was abdominal in 42 patients, mediastinal in 27 a...

M G Mott, O B Eden, M K Palmer in British Journal of Cancer (1984)

Article

Prevalence of oral colonization with Candida albicans and anti-C. albicans IgA in the saliva of normal children and children with acute lymphoblastic leukaemia

The prevalence of oral colonization with C. albicans was studied in 40 children with acute lymphoblastic leukaemia (ALL) and 40 matched normal children. Colonization was more common in the ALL group (25% colonize...

T. A. Gentle, Dr. D. W. Warnock, O. B. Eden in Mycopathologia (1984)