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Article
Open AccessExtra kinetic dimensions for label discrimination
Due to its sensitivity and versatility, fluorescence is widely used to detect specifically labeled biomolecules. However, fluorescence is currently limited by label discrimination, which suffers from the broad...
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Chapter and Conference Paper
A Rumor Detection Method Based on Graph Convolutional Network
With the rapid development of network media, it becomes easier to spread rumors, which makes the research on rumor detection more urgent. The current automatic rumor detection methods focus on modeling by arti...
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Article
Multiple and integrated functions of floral C-class MADS-box genes in flower and fruit development of Physalis floridana
This work reveals potentially multiple and integrated roles in flower and fruit development of floral C-class MADS-box genes in Physalis.
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Article
Solidification Behavior of in situ TiB2/Cu Composite Powders during Reactive Gas Atomization
2wt% TiB2/Cu composite powders were fabricated in situ by reactive gas atomization. The fabricated composite powder exhibits high sphericity, and the powder sizes range from 5 µm to 150 µm. The morphology of the ...
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Chapter and Conference Paper
Real World Third-Person with Multiple Point-of-Views for Immersive Mixed Reality
Technologies of Virtual Reality (VR), Augmented Reality (AR) and Mixed Reality (MR) are increasingly applied in urban construction and smart cities. As one of the high fidelity revivification methods, the purp...
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Article
mEosEM withstands osmium staining and Epon embedding for super-resolution CLEM
Super-resolution correlative light and electron microscopy (SR-CLEM) is a powerful approach for imaging specific molecules at the nanoscale in the context of the cellular ultrastructure. Epon epoxy resin embed...
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Article
Open AccessHessian single-molecule localization microscopy using sCMOS camera
Single-molecule localization microscopy (SMLM) has the highest spatial resolution among the existing super-resolution imaging techniques, but its temporal resolution needs further improvement. An sCMOS camera ...
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Article
Open AccessLive cell single molecule-guided Bayesian localization super resolution microscopy
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Chapter and Conference Paper
WAR Bots: Combining Virtual and Augmented Realities for an Immersive and Enjoyable Gaming Experience
Despite the popularity of Augmented and Virtual Reality within gaming, the full potential of such technologies is yet to be fully taken advantage of. Thus, we introduce WAR Bots, a cyber-physical game which inten...
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Article
Open AccessReduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro
Aminoglycosides are ototoxic to the cochlear hair cells and mitochondrial dysfunction is one of the major mechanisms behind ototoxic drug-induced hair cell death. TRMU (tRNA 5-methylaminomethyl-2-thiouridylate...
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Article
Open Access2-Aminoethoxydiphenyl Borate Potentiates CRAC Current by Directly Dilating the Pore of Open Orai1
2-Aminoethoxydiphenyl borate (2-APB) elicits potentiation current (Ip) on Ca2+ release-activated Ca2+ (CRAC) channels. An accurate investigation into this modulation mechanism would reveal how STIM1-dependent cha...
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Article
Research and design of reconfigurable composite field multiplication in symmetric cipher algorithms
The composite field multiplication is an important and complex module in symmetric cipher algorithms, and its realization performance directly restricts the processing speed of symmetric cipher algorithms. Bas...
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Article
Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming
Crystallographic and functional studies reveal the arch-shaped architecture of the Munc13 MUN domain and show the molecular basis for Munc13's role in synaptic-vesicle priming by mediating syntaxin-1 opening a...
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Article
Open AccessBayesian localization microscopy based on intensity distribution of fluorophores
Super-resolution microscopy techniques have overcome the limit of optical diffraction. Recently, the Bayesian analysis of Bleaching and Blinking data (3B) method has emerged as an important tool to obtain supe...
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Article
Open AccessDrift correction for single-molecule imaging by molecular constraint field, a distance minimum metric
The recent developments of far-field optical microscopy (single molecule imaging techniques) have overcome the diffraction barrier of light and improve image resolution by a factor of ten compared with convent...
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Article
Open AccessThe specific and rapid labeling of cell surface proteins with recombinant FKBP-fused fluorescent proteins
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Chapter and Conference Paper
Dynamics and Control of an Active Magnetic Bearing-Rotor System with Time Delay
Time delay in digital control loop, which is usually neglected in most of the research in electromechanical systems, may have great influence on the performance of high-speed active magnetic bearing (AMB) syst...
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Article
Ultrafast, accurate, and robust localization of anisotropic dipoles
The resolution of single molecule localization imaging techniques largely depends on the precision of localization algorithms. However, the commonly used Gaussian function is not appropriate for anisotropic di...
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Article
Rational design of true monomeric and bright photoactivatable fluorescent proteins
Structure determination followed by targeted engineering of the popular photoactivatable fluorescent protein monomeric (m)Eos2 yields mEos3 versions that are more monomeric and less disruptive in protein fusio...
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Article
The Late Pleistocene lacustrine deposit and paleobotanic assemblage in the Putuo Mountain, Zhejiang