Search
Search Results
-
Generation Method of Dynamic Alarm Baseline for Cloud Server Based on XGBoost and Tolerability
In order to solve the problem that massive server alarm management of cloud data centers in electric power enterprises cannot adapt to the...
-
Effects of a Long-Acting Diquafosol Ophthalmic Solution on the Ocular Surface, Tolerability, and Usability in Dry Eye Disease
IntroductionThis study aimed to investigate the tolerability of high-viscosity diquafosol tetrasodium (DQS) ophthalmic solution (DIQUAS LX; DQSLX)...
-
Tolerability of Antihypertensive Medications: The Influence of Age
IntroductionDespite high prevalence of hypertension, few studies have analysed the adverse effects (AEs) of antihypertensive medications, especially...
-
Safety and Tolerability of Rituximab in the Treatment of Systemic Sclerosis
AbstractRituximab (RTX) has been used for the treatment of systemic sclerosis (SSс) for a long time and has shown good efficacy for skin fibrosis and...
-
Real-World Evidence of Tolerability of 20% Subcutaneous Immunoglobulin Treatment
PurposeThe safety and efficacy of subcutaneous immune globulin 20% (human) solution (Ig20Gly) were demonstrated in clinical trials. However,...
-
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Oral AL01211 in Healthy Chinese Volunteers
Background and ObjectiveAberrant accumulation of glycosphingolipids (GSLs) in the lysosome leads to GSL storage diseases. Glucosylceramide synthase...
-
Long-Term Efficacy and Tolerability of PCSK9 Targeted Therapy: A Review of the Literature
Increased plasma levels of low-density lipoprotein cholesterol (LDL-C) are causally associated with atherosclerotic cardiovascular disease (ASCVD),...
-
Design of mobile and website health application devices for drug tolerability in hereditary fructose intolerance
BackgroundHereditary fructose intolerance (HFI) is a rare metabolic disease caused by aldolase B deficiency. The aim of our study was to analyse...
-
Safety and Tolerability of Combining CGRP Monoclonal Antibodies with Gepants in Patients with Migraine: A Retrospective Study
IntroductionThe introduction of clacitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) has revolutionized the treatment of migraines. In...
-
Mesenchymal Stem Cell Therapy in Acute Intracerebral Hemorrhage: A Dose-Escalation Safety and Tolerability Trial
BackgroundWe conducted a preliminary phase I, dose-escalating, safety, and tolerability trial in the population of patients with acute intracerebral...
-
Assessing the safety and tolerability of rhinologic surgery under local anesthetic: an 8-year retrospective analysis
PurposeOffice-based rhinologic procedures (OBRP) have become widely available in North America due to technological advances and appropriate patient...
-
Pharmacokinetics, Safety, and Tolerability of Single-Dose Orally Administered Venglustat in Healthy Chinese Volunteers
Background and ObjectiveDeficiencies of enzymes acting downstream of glucosylceramide synthase (GCS) can cause severe substrate accumulation....
-
Efficacy and Tolerability of Intranasal Midazolam Administration for Antiseizure Treatment in Adults: A Systematic Review
ObjectiveThe objective of this study was to assess the efficacy and tolerability of intranasal midazolam (in-MDZ) administration for antiseizure...
-
Tolerability of Fe35Ni35Cr20Mn10 Multi-principal-component Alloy to Impurity Elements
Two nominal Fe35Ni35Cr20Mn10 (in at.%) multi-principal-component alloys (MCAs) were prepared in vacuum-induction furnace with industrial purity...
-
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Stapokibart in Healthy Volunteers and Adult Subjects with Atopic Dermatitis
IntroductionStapokibart, a novel humanized anti-interleukin (IL)-4 receptor alpha monoclonal antibody, inhibits the signaling of IL-4 and IL-13,...
-
Tolerability and effectiveness of palbociclib in older women with metastatic breast cancer
PurposePalbociclib has become the standard of care for estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 negative (HER2-)...
-
An open-label pilot trial assessing tolerability and feasibility of LSD microdosing in patients with major depressive disorder (LSDDEP1)
BackgroundGlobally, an estimated 260 million people suffer from depression [1], and there is a clear need for the development of new, alternative...
-
Safety and tolerability of Sacubitril/Valsartan in heart failure patient with reduced ejection fraction
BackgroundAngiotensin receptor blocker and a neprilysin inhibitor (ARNI) has emerged as an innovative therapy for patients of heart failure with...
-
Safety, Tolerability and Pharmacokinetics of Single-Dose Oral SYHA1402 in Healthy Chinese Subjects
IntroductionTo assess the safety, tolerability and pharmacokinetics of a single dose of SYHA1402 in healthy Chinese subjects.
Methods ...
-
The Real-World Effectiveness and Tolerability of a Soothing Cream Containing the Postbiotic Aquaphilus dolomiae Extract-G2 for Skin Healing
IntroductionIn vitro and pre-marketing clinical data have shown the healing properties of a postbiotic extract from Aquaphilus dolomiae (ADE-G2)....
