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Signaling Pathways in Plant Responses to Abiotic Stress
Recent scientific advancements have significantly improved our understanding of plant signaling pathways under abiotic stress. However, further...
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Signaling Pathways Regulating Cartilage Formation
Over the course of many years of investigation, the molecular processes that regulate the differentiation of chondrocytes throughout the development...
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Metabolites of Chemical Signaling Pathways from Crop–Microbe Interactions
Crop–microbe interactions play an important role in plant growth, development, and health. These interactions are mediated by chemical signals, which...
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Inter- and Intracellular Signaling Pathways
Cardiovascular diseases, both congenital and acquired, are the leading cause of death worldwide, associated with significant health consequences and...
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Signaling pathways of dental implants’ osseointegration: a narrative review on two of the most relevant; NF-κB and Wnt pathways
IntroductionCell signaling pathways are the biological reactions that control cell functions and fate. They also directly affect the body reactions...
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The interplay between Wnt signaling pathways and microtubule dynamics
Wnt signaling pathways represent an evolutionarily highly conserved, intricate network of molecular interactions that regulates various aspects of...
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Cardiac optogenetics: shining light on signaling pathways
In the early 2000s, the field of neuroscience experienced a groundbreaking transformation with the advent of optogenetics. This innovative technique...
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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis
Endometriosis is linked to increased infertility and pregnancy complications due to defective endometrial decidualization. We hypothesized that...
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Germline determinants of aberrant signaling pathways in cancer
Cancer is a complex disease influenced by a heterogeneous landscape of both germline genetic variants and somatic aberrations. While there is growing...
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Signaling Pathways in Neurological Cancers
Neural cancer is among the most aggressive and difficult-to-treat malignancies. There are over 100 subtypes of brain tumors, which make this type of...
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Intrinsic Signaling Pathways and key Regulatory Factors of Stomatal Development
Stomata are small pores on the surface of plant leaves that play a critical role in regulating gas exchange and water loss. The development of...
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Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds
Wound healing is a tightly regulated process that ensures tissue repair and normal function following injury. It is modulated by activation of...
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The interaction between ferroptosis and inflammatory signaling pathways
Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation. Inflammation is one common and effective physiological...
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Tight Junctions and Signaling Pathways in Cancer
Tight junctions (TJs) are intercellular connections that close the gap between the individual cells and limit the paracellular entry of harmful...
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When AHR signaling pathways meet viral infections
Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcriptional factor widely expressed among immune, epithelial, endothelial and stromal cells...
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Metabolic Pathways and Cell Signaling
This chapter overviews the basic features of metabolic pathways concerning the three main classes of energetic substrates – carbohydrates, lipids and...
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Roles and Mechanisms of miRNAs in Abdominal Aortic Aneurysm: Signaling Pathways and Clinical Insights
Purpose of ReviewAbdominal aortic aneurysm refers to a serious medical condition that can cause the irreversible expansion of the abdominal aorta,...
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Exosome Content–Mediated Signaling Pathways in Multiple Sclerosis
Exosomes are small extracellular vesicles with a complex lipid-bilayer surface and 30–150 nm diameter. These vesicles play a critical role in...
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Signaling pathways in colorectal cancer implications for the target therapies
Colorectal carcinoma (CRC) stands as a pressing global health issue, marked by the unbridled proliferation of immature cells influenced by...
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Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects more than 500 million population worldwide. OA was...
