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Oral quinolones versus intravenous β-lactam for the treatment of acute focal bacterial nephritis: a retrospective cohort study
BackgroundEvidence regarding the best antibiotic regimen and the route of administration to treat acute focal bacterial nephritis (AFBN) is scarce....
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Together or Apart? Revealing the Impact of Dietary Interventions on Bioavailability of Quinolones: A Systematic Review with Meta-analyses
Background and ObjectiveManaging drug-food interactions is essential for optimizing the effectiveness and safety profile of quinolones. Following...
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Safety of Quinolones in Children: A Systematic Review and Meta-Analysis
BackgroundThe results of animal experiments show that quinolone antibacterial drugs may permanently damage the soft tissues of the weight-bearing...
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Microwave-Assisted Synthesis and Functionalization of 2-Pyridones, 2-Quinolones and Other Ring-Fused 2-Pyridones
2-pyridones are important heterocycles with great applicability in medicinal chemistry and this core structure can be found in compounds with...
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Quinolones
Nalidixic acid was the first quinolone introduced in 1962. Structural changes have resulted in an extended spectrum and better pharmacokinetics...
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A review on the synthesis of heteroannulated quinolones and their biological activities
AbstractThe quinoline scaffold has become an important construction motif for the development of new drugs. The quinolones and their heteroannulated...
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Simultaneous determination of four quinolones in honey by nickel/aluminum-layered double hydroxide-based air-assisted dispersive solid-phase extraction and high-performance liquid chromatography
A novel air-assisted dispersive solid-phase extraction method based on nickel/aluminum-layered double hydroxides combined with high performance...
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Ionic liquid-based dispersive liquid–liquid microextraction followed by magnetic solid-phase extraction for determination of quinolones
An ionic liquid-based dispersive liquid–liquid microextraction (IL-DLLME) combined with magnetic solid-phase extraction (MSPE) was developed for...
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Efficacy and safety of quinolones vs. other antimicrobials for the treatment of uncomplicated urinary tract infections in adults: a systematic review and meta-analysis
Introduction and hypothesisIn the present study, we aimed to compare the efficacy and safety of quinolones with trimethoprim-sulfamethoxazole...
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Single-Step Capture and Targeted Metabolomics of Alkyl-Quinolones in Outer Membrane Vesicles (OMVs) of Pseudomonas Aeruginosa
Outer membrane vesicles (OMVs), also called as bacterial membrane vesicles (BMVs), are secreted by many Gram-negative bacterial pathogens. These...
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Systemic quinolones and risk of retinal detachment III: a nested case–control study using a US electronic health records database
BackgroundQuinolones are popular antibiotics that are known for their potency, broad coverage, and reasonable safety. Concerns have been raised about...
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Digital Colorimetry of Indicator Test-Systems Using a Smartphone and Chemometric Analysis in Determination of Quinolones in Pharmaceuticals
A combined approach was developed for the identification and determination of quinolone antibiotics in pharmaceuticals using solid-state fluorescence...
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Sorption-Fluorimetric Determination of Quinolones in Waste and Natural Waters with a Smartphone
AbstractA simple, affordable, and safe (green chemistry) method is proposed for determining 17 quinolone antibiotics in waste and natural waters by...
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Genomic Characterization of Salmonella enterica Resistant to Cephalosporin, Quinolones, And Macrolides
Salmonella enterica subsp. enterica ( Salmonella ), one of the most common causes of bacterial foodborne infections, causes salmonellosis, which is...
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Facile synthesis of new pyrano[3,2-c]quinolones via the reaction of quinolin-2-ones with ethene-1,2,3,4-tetracarbonitrile
Synthesis of heteroannulated pyrano[3,2- c ]quinolones was established starting from the reaction of 4-hydroxyquinolin-2-ones with...
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Multi-templates surface molecularly imprinted polymer for simultaneous and rapid determination of sulfonamides and quinolones in water: effect of carbon-carbon double bond
In this work, the effect of a carrier modified with a carbon-carbon double bond (C=C) on preparing multi-templates surface molecularly imprinted...
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Sulfonamides, Quinolones, and Agents for Urinary Tract Infections
Sulphonamides and related agents hold historical significance since they are among the very first antimicrobials found to be effective for human use....
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Design, Synthesis, SAR, Pharmacokinetic Prediction of New 4-Quinolones as Anti-Microbial Agents
Abstracts of new 4-quinolone derivatives was synthesized by conventional heating method. For the synthesized compounds, we performed pharmacokinetic...
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Potentials of N-(2, 4-dinitro-1-naphthyl)-p-toluenesulphonamide and 2, 4-dinitro-1-naphthol as novel charge transfer acceptors in pharmaceutical analysis of some quinolones and cephalosporins
BackgroundQuinolones and cephalosporins are antibiotic agents with activity against Gram-positive and Gram-negative bacteria. They contain...
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Application of RP-HPLC method for the simultaneous determination of cetirizine in the presence of quinolones
BackgroundPresent work describes a fast, simple, and sensitive procedure for the simultaneous determination of cetirizine in the presence of...
