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A tri-fluid tortuous microfluidic chip for green synthesis of nanoparticles and inactivation of a model gram-negative bacteria: Intracellular components evaluation
The development of green synthesis route using plant extract as a simple, cost-effective, and eco-friendly method for the synthesis of nanoparticles...
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Huntingtin, the Major Factor in Huntington’s Disease Development. Main Functions and Intracellular Proteolysis
AbstractThis review is devoted to the consideration of pathological intracellular mechanisms characteristic of Huntington’s disease and the central...
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Coupling of nanostraws with diverse physicochemical perforation strategies for intracellular DNA delivery
Effective intracellular DNA transfection is imperative for cell-based therapy and gene therapy. Conventional gene transfection methods, including...
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Electroactive nanoinjection platform for intracellular delivery and gene silencing
BackgroundNanoinjection—the process of intracellular delivery using vertically configured nanostructures—is a physical route that efficiently...
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New Frontiers on Intracellular cGAS Activation: Molecular Mechanisms, Cellular Signaling, and Therapeutic Strategies
Cyclic GMP-AMP (cGAMP) synthase (cGAS) plays a pivotal role in the innate immune system. As the primary DNA sensor in cells, cGAS binds to dsDNA in...
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Designing bioresponsive nanomaterials for intracellular self-assembly
Supramolecular assemblies are essential components of living organisms. Cellular scaffolds, such as the cytoskeleton or the cell membrane, are formed...
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Characterization, components, and chemical structure of a novel natural pigments derived from Streptomyces tauricus
Microbial pigments have extensive applications in the food, cosmetic, and biopharmaceutical industries. In this study, a pigment-rich actinomycete...
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Link between organic nanovescicles from vegetable kingdom and human cell physiology: intracellular calcium signalling
BackgroundPlant-derived nanovesicles (PDNVs) are a novelty in medical and agrifood environments, with several studies exploring their functions and...
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Hydrogels as functional components in artificial cell systems
Recent years have seen substantial efforts aimed at constructing artificial cells from various molecular components with the aim of mimicking the...
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Effect of fatty acids on intracellular pneumocandin B0 storage in the fermentation of Glarea lozoyensis
The natural product pneumocandin B 0 is the precursor of the antifungal drug caspofungin. To explore the relationship between pneumocandin B 0 and oil....
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Intracellular removal of acetyl, feruloyl and p-coumaroyl decorations on arabinoxylo-oligosaccharides imported from lignocellulosic biomass degradation by Ruminiclostridium cellulolyticum
BackgroundXylans are polysaccharides that are naturally abundant in agricultural by-products, such as cereal brans and straws. Microbial degradation...
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Ammonium sulfate supplementation enhances erythromycin biosynthesis by augmenting intracellular metabolism and precursor supply in Saccharopolyspora erythraea
In this study, the cellular metabolic mechanisms regarding ammonium sulfate supplementation on erythromycin production were investigated by employing...
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Specific intracellular signature of SARS-CoV-2 infection using confocal Raman microscopy
SARS-CoV-2 infection remains spread worldwide and requires a better understanding of virus-host interactions. Here, we analyzed biochemical...
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Delivery of Antibiotics by Cell-Penetrating Peptides to Kill Intracellular Pathogens
In the last decades, the increasing rate of multidrug-resistant bacteria to classical antibiotics has driven research towards identification of other...
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Probiotic Potential of Bacteria Isolated from Huauzontle (Chenopodium berlandieri spp. Nuttalliae) and Multifunctional Properties of Their Intracellular Contents
The aim of the present work was to assess the probiotic potential of lactic acid bacteria (LAB) isolated from huauzontle ( Chenopodium berlandieri ...
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Use of nanocellulose in the intracellular delivery of biological and non-biological drugs: a review
The need for natural, biodegradable, and biocompatible nanomaterials in drug delivery led to a great deal of interest in develo**...
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Study on the intracellular adaptative mechanism of Acidithiobacillus caldus MTH-04 to NaCl stress
To understand the adaptive mechanism of bioleaching microorganism Acidithiobacillus caldus MTH-04, its physiology and metabolic changes at the...
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Effect of the dinitrosyl iron complex with N-ethylthiourea on ROS and NO intracellular levels and caspase activity in HeLa tumor cells
The kinetics of intracellular accumulation of nitrogen monoxide and reactive oxygen species under the action of various concentrations of the...
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The complex landscape of intracellular signalling in protein modification under hyperglycaemic stress leading to metabolic disorders
Hyperglycaemia is a life-threatening risk factor that occurs in both chronic and acute phases and has been linked to causing injury to many organs....
