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Biophysical chemistry

How membranes influence intracellular phase separation

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Liquid–liquid phase separation (LLPS) within cells is a captivating phenomenon known to aid the organization of cellular components; however, its complex kinetics have remained a puzzle. Now, a new study elucidates the crosstalk between the phase state of an encapsulating membrane and LLPS dynamics.

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Fig. 1: Response of vesicles loaded with PEG and dextran when exposed to osmotic deflation.

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  1. Max Planck Institute of Colloids and Interfaces, Science Park Golm, Potsdam, Germany

    Rumiana Dimova

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  1. Rumiana Dimova
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Correspondence to Rumiana Dimova.

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Dimova, R. How membranes influence intracellular phase separation. Nat. Chem. 16, 10–11 (2024). https://doi.org/10.1038/s41557-023-01407-7

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