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Communication in miRNAs Between Inflammation and Cancer
Inflammatory and immune responses are controlled by microRNAs (miRNAs), and cancer is also regulated by miRNAs. Computing analysis and evidence from...
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Integrated Analysis and Identification of CSF-Derived Risk miRNAs and Pivotal Genes in Multiple Sclerosis
Multiple sclerosis (MS) is a common chronic autoimmune disorder of the central nervous system that predominantly affects young adults. Mounting...
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Diagnostic, Prognostic and Theranostic Potential of miRNAs in Prostate Cancer
A novel class of gene regulators, small noncoding RNAs or microRNAs (miRNAs) has an important role in various malignancies, including prostate cancer...
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Vitamins A and D Enhance the Expression of Ror-γ-Targeting miRNAs in a Mouse Model of Multiple Sclerosis
Autoreactive T cells, particularly those characterized by a Th17 phenotype, exert significant influence on the pathogenesis of multiple sclerosis...
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Deep Learning of miRNAs for Therapeutic Applications
The RNA Precious Medical Initiative requires a safe, affordable, and sustainable device as an administration tool. Why do microRNA (miRNA) quantum...
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Understanding the multifaceted role of miRNAs in Alzheimer’s disease pathology
Small non-coding RNAs (miRNAs) regulate gene expression by binding to mRNA and mediating its degradation or inhibiting translation. Since miRNAs can...
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miRNAs in pancreatic cancer progression and metastasis
Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells. Dysregulation of miRNA expression and function has been linked...
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miRNAs contributing to the repair of tendon injury
Tendon injury is one of the most common disorders of the musculoskeletal system, with a higher likelihood of occurrence in elderly individuals and...
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HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer
BackgroundCervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer,...
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Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that affects nerve cells in the brain and spinal cord, causing loss of...
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CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines
BackgroundGenome-wide functional screening using the CRISPR-Cas9 system is a powerful tool to uncover tumor-specific and common genetic dependencies...
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MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage
Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke, most often occurring between the ages of 45 and 60....
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Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression
In recent decades, colorectal cancer (CRC) has turned into one of the most widespread malignancies, and the incidence of this malignancy is expected...
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From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response
Pheochromocytoma (PCC) is a neuroendocrine tumor that produces and secretes catecholamine from either the adrenal medulla or extra-adrenal locations....
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Identification and Characterization of Evolutionary Conserved Muskmelon Non-coding miRNAs and Their Target Proteins
MicroRNAs (miRNAs) are short, endogenously encoded small RNAs, 18–26 nucleotides in length, which can posttranscriptionally regulate gene expression...
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Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition
BackgroundReverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and...
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The interplay of miRNAs and ferroptosis in diseases related to iron overload
Ferroptosis has been conceptualized as a novel cell death modality distinct from apoptosis, necroptosis, pyroptosis and autophagic cell death. The...
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Screening and identification of specific cluster miRNAs in N2a cells infected by H7N9 virus
This study aims to screen and identify specific cluster miRNAs of H7N9 virus-infected N2a cells and explore the possible pathogenesis of these...
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Discerning the Prospects of miRNAs as a Multi-Target Therapeutic and Diagnostic for Alzheimer’s Disease
Although over the last few decades, numerous attempts have been made to halt Alzheimer’s disease (AD) progression and mitigate its symptoms, only a...
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Next-generation sequencing profiling of miRNAs in individuals with 22q11.2 deletion syndrome revealed altered expression of miR-185-5p
BackgroundThe 22q11.2 deletion syndrome (22q11.2DS) is a microdeletion syndrome with highly variable phenotypic manifestations, even though most...
