20 Result(s)

Article

A morphological study of adipose-derived stem cell sheets created with temperature-responsive culture dishes using scanning electron microscopy

Adipose-derived stem cell (ADSC) sheets have potential to be effective in various therapies. In this study, we first demonstrated that a cell sheet composed of human ADSCs could be created using a new temperat...

Yasuhiko Taki, Atsushi Fuku, Yuka Nakamura, Terutsugu Koya… in Medical Molecular Morphology (2022)

Article

2019 Updated diagnostic criteria and disease severity classification for TAFRO syndrome

Yasufumi Masaki, Hiroshi Kawabata, Kazue Takai… in International Journal of Hematology (2020)

Article

High FDG uptake on PET is associated with negative cell-to-cell adhesion molecule E-cadherin expression in lung adenocarcinoma

E-cadherin is a main cell-to-cell adhesion molecule. A negative expression of E-cadherin correlates with distant metastasis in lung cancer. Recently, it was reported that there is an association between FDG up...

Kotaro Higashi, Yoshimichi Ueda, Miyako Shimasaki… in Annals of Nuclear Medicine (2017)

Article

Correlation of HIF-1α/HIF-2α expression with FDG uptake in lung adenocarcinoma

Hypoxia is a key element involved in the development and progression of tumors. HIF-1α may transiently induce and mediate the response to acute and severe hypoxia, while HIF-2α may induce a longer response and...

Kotaro Higashi, Toshiaki Yamagishi, Yoshimichi Ueda… in Annals of Nuclear Medicine (2016)

Article

Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 version

TAFRO syndrome is a systemic inflammatory disorder characterized by thrombocytopenia, anasarca including pleural effusion and ascites, fever, renal insufficiency, and organomegaly including hepatosplenomegaly ...

Yasufumi Masaki, Hiroshi Kawabata, Kazue Takai… in International Journal of Hematology (2016)

Article

Regulation of soluble Flt-1 (VEGFR-1) production by hnRNP D and protein arginine methylation

Soluble fms-like tyrosine kinase-1 (sFlt-1) functions as a potent inhibitor of angiogenesis by trap** vascular endothelial growth factor (VEGF). However, the precise regulatory mechanism of sFlt-1 production...

Takayuki Ikeda, Yasuo Yoshitomi, Hidehito Saito… in Molecular and Cellular Biochemistry (2016)

Article

RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells

RBM8A (Y14) is carrying RNA-binding motif and forms the tight heterodimer with MAGOH. The heterodimer is known to be a member of exon junction complex on exporting mRNA and is required for mRNA metabolisms su...

Yasuhito Ishigaki, Yuka Nakamura, Takanori Tatsuno… in Histochemistry and Cell Biology (2014)

Article

Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine

Pancreatic cancer is obstinate and resistant to gemcitabine, a standard chemotherapeutic agent for the disease. We previously showed a therapeutic effect of glycogen synthase kinase-3β (GSK3β) inhibition again...

Takeo Shimasaki, Yasuhito Ishigaki, Yuka Nakamura… in Journal of Gastroenterology (2012)

Article

Use of ionic liquid in fungal taxonomic study of ultrastructure of basidiospore ornamentation

An ionic liquid (IL) is a kind of salt that stays in a molten state even at room temperature. Since ILs do not vaporize even under vacuum conditions and show high ionic conductivity, they can be used in scanni...

Konomi Yanaga, Nitaro Maekawa, Norihiro Shimomura… in Mycological Progress (2012)

Chapter and Conference Paper

Stress Responses of Pancreatic Cancer Cells and Their Significance in Invasion and Metastasis

Stress responses of pancreatic cancer cells are detected in case of ­chemotherapy. We have reported the expression of various stress proteins in ­pancreatic cancer cells with special reference to tumor aggress...

Yoshiharu Motoo, Qi-Sheng **a, Naoki Nakaya, Takeo Shimasaki… in The Primo Vascular System (2012)

Article

VEGF-A and its isoform VEGF₁₂₁ mRNA expression measured by quantitative real-time RT-PCR: correlation with F-18 FDG uptake and aggressiveness of lung adenocarcinoma: preliminary study

To investigate the correlation of vascular endothelial growth factor (VEGF) A and its isoform VEGF ₁₂₁ mRNA expression with F-18 fluorodeoxyglucose (FDG) uptake and aggressiveness in lung adenocarcinoma.

JianFei Guo, Kotaro Higashi, Yoshimichi Ueda… in Annals of Nuclear Medicine (2011)

Article

Assessment of VEGF-D expression measured by immunohistochemical staining and F-18 FDG uptake on PET as biological prognostic factors for recurrence in patients with surgically resected lung adenocarcinoma

To assess whether the combined evaluation of vascular endothelial growth factor D (VEGF-D) expression and fluorodeoxyglucose (FDG) uptake correlates with lymph node metastasis and post-operative recurrence in ...

Lina Zhang, Kotaro Higashi, Yasuhito Ishigaki… in Annals of Nuclear Medicine (2010)

Protocol

Optimized Gene Silencing by Co-expression of Multiple shRNAs in a Single Vector

Currently, RNA interference technology is one of the most powerful tools in molecular biology and has been widely used in genetic manipulation. In addition to chemically synthesized small interfering RNA (siRN...

Yasuhito Ishigaki, Akihiro Nagao, Tsukasa Matsunaga in RNA Interference (2010)

Article

Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1

The authors recently demonstrated that the mitochondrial voltage-dependent anion channel 1 (VDAC1) is involved in the sensitivity of cancer cells to furanonaphthoquinone (FNQ). The aim of the present study was...

Eriko Simamura, Hiroki Shimada, Yasuhito Ishigaki… in Anatomical Science International (2008)