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  1. Article

    Open Access

    Surgical implantation of human adipose derived stem cells attenuates experimentally induced hepatic fibrosis in rats

    Mesenchymal stem cells (MSCs) are multipotent stromal cells and could exert hepatoprotective effects against acute liver injury, steatohepatitis, and fibrogenesis. Here, we evaluated the effects of human adipo...

    Masateru Nomura, Joseph George, Chieko Hashizume, Takashi Saito in Molecular Medicine (2022)

  2. Article

    Open Access

    Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation

    There are two isoforms of sphingomyelin synthase (SMS): SMS1 and SMS2. SMS1 is located in the Golgi apparatus only while SMS2 is located in both the plasma membrane and the Golgi apparatus. SMS1 and SMS2 act s...

    Goichi Matsumoto, Chieko Hashizume, Ken Watanabe, Makoto Taniguchi in Molecular Medicine (2019)

  3. Article

    Open Access

    Characterization of the role of the tumor marker Nup88 in mitosis

    Nuclear pore complexes are massive multiprotein channels responsible for traffic between the nucleus and cytoplasm, and are composed of approximately 30 proteins, termed nucleoporins (Nup). Our recent studies ...

    Chieko Hashizume, Hiroshi Nakano, Kimihisa Yoshida, Richard W Wong in Molecular Cancer (2010)