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Article
Indole-3-acetic acid correlates with monocyte-to-high-density lipoprotein (HDL) ratio (MHR) in chronic kidney disease patients
Indole-3-acetic acid is a protein-bound indolic uremic toxin deriving from tryptophan metabolism. Increased levels are associated with higher thrombotic risk and both cardiovascular and all-cause mortality. An...
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Article
Monocyte to HDL ratio: a novel marker of resistant hypertension in CKD patients
Inflammation, oxidative stress (OS), atherosclerosis and resistant hypertension (RH) are common features of chronic kidney disease (CKD) leading to a higher risk of death from cardiovascular disease. These eff...
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Article
RAS inhibition modulates kynurenine levels in a CKD population with and without type 2 diabetes mellitus
Kynurenine pathway of tryptophan metabolism is involved in the pathophysiology of chronic kidney disease (CKD) and diabetes mellitus, mainly through the inflammation-induced activity of indoleamine 2,3-dioxyge...
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Article
Open AccessManagement of dyslipidaemia in patients with chronic kidney disease: a position paper endorsed by the Italian Society of Nephrology
Chronic kidney disease (CKD) represents a major public health issue worldwide and entails a high burden of cardiovascular events and mortality. Dyslipidaemia is common in patients with CKD and it is characteri...
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Article
Negative Emotions in End-Stage Renal Disease: Are Anxiety Symptoms Related to Levels of Circulating Catecholamines?
The purpose of this study was to assess depression and anxiety levels and possible correlations with levels of circulating catecholamines in maintenance hemodialysis (MHD) and Conservative care (CC) ERSD patie...
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Article
Acetate-free biofiltration to remove fibroblast growth factor 23 in hemodialysis patients: a pilot study
Serum levels of 32 kDa-phosphaturic hormone fibroblast growth factor 23 (FGF23) rise early in renal failure in order to keep phosphatemia within the normal range; however, this compensatory mechanism itself co...
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Article
Renoprotective effect of erythropoietin in zebrafish after administration of gentamicin: an immunohistochemical study for β-catenin and c-kit expression
Gentamicin is an aminoglycoside antibiotic widely used in the treatment of infections caused by Gram-negative bacteria. The main limitation to its therapeutic effectiveness is the potential nephrotoxicity. Ery...
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Article
Salt–water imbalance and fluid overload in hemodialysis patients: a pivotal role of corin
Natriuretic peptides (NP) play a key role in regulation of salt and water balance. Corin, a serine protease which activates NP, plays a key role in regulation of blood pressure and cardiac function. The aim of...
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Article
Kidney-lung connections in acute and chronic diseases: current perspectives
Lung and kidney functions are intimately related in both health and disease. The regulation of acid–base equilibrium, modification of partial pressure of carbon dioxide and bicarbonate concentration, and the c...
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Article
Kidney disease and psoriasis: novel evidences beyond old concepts
Psoriasis is an immune-mediated inflammatory disease for a long time considered as a type of pathology characterized by an exclusive skin involvement. Recently it has been shown that patients affected by this ...
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Reference Work Entry In depth
Apelin and Copeptin as Biomarkers of Kidney Disease
The need for faster diagnosis, more accurate prognostic assessment, and treatment decisions in renal diseases has led to the investigations of new biomarkers. Arginine vasopressin (AVP) is one of the main horm...
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Reference Work Entry In depth
Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology
Neutrophil gelatinase-associated lipocalin (NGAL) is a small 25-kD peptide belonging to the lipocalin superfamily. It mainly binds to siderophores, iron-carrying molecules which are essential to bacterial and ...
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Living Reference Work Entry In depth
Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology
Neutrophil gelatinase-associated lipocalin (NGAL) is a small 25-kD peptide belonging to the lipocalin superfamily. It mainly binds to siderophores, iron-carrying molecules which are essential to bacterial and ...
-
Living Reference Work Entry In depth
Apelin and Copeptin as Biomarkers of Kidney Disease
The need for faster diagnosis, more accurate prognostic assessment, and treatment decisions in renal diseases has led to the investigations of new biomarkers. Arginine vasopressin (AVP) is one of the main horm...
