53 Result(s)

Article

Identification of a plausible serum uric acid cut-off value as prognostic marker of stroke: the Uric Acid Right for Heart Health (URRAH) study

The Working Group on Uric Acid and Cardiovascular Risk of the Italian Society of Hypertension conceived and designed an ad hoc study aimed at searching for prognostic cut-off values of serum uric acid (SUA) in...

Valérie Tikhonoff, Edoardo Casiglia, Paolo Spinella… in Journal of Human Hypertension (2022)

Article

Low eGFR and albuminuria independently predict all-cause mortality in high-risk subjects undergoing coronary arteriography

Individuals with Chronic Kidney Disease (CKD) are at high risk for cardiovascular morbidity and mortality. The aim of this study was to examine the relationship between renal dysfunction and all-cause mortalit...

Maria Maddalena D’Errico, Pamela Piscitelli… in Internal and Emergency Medicine (2022)

Article

Expanding the therapy options for diabetic kidney disease

New DAPA-CKD trial analyses have confirmed the outstanding renoprotective benefits of sodium–glucose co-transporter 2 inhibitors, independently of the presence of diabetes or the stage of kidney disease. Moreo...

Paola Fioretto, Roberto Pontremoli in Nature Reviews Nephrology (2022)

Article

Possible Advantages Deriving from Patiromer Use in Hypertensive Patients Made Hyperkalemic by Renin–Angiotensin–Aldosterone Blocking Agents

Hyperkalemia is an elevated level of serum potassium (K⁺) and does represent a life-threatening condition. In clinical practice, hyperkalemia mainly derives from an impaired renal K⁺ excretion which, in turn, is ...

Claudio Borghi, Claudio Ferri… in High Blood Pressure & Cardiovascular Preve… (2021)

Article

Atherogenic dyslipidemia and diabetic nephropathy

Chronic kidney disease is associated with altered lipid metabolism and lipid accumulation. Although it is though that hyperlipemia is a consequence of kidney dysfunction, several lines of evidence support that...

Giuseppina Russo, Pamela Piscitelli, Annalisa Giandalia… in Journal of Nephrology (2020)

Article

Characteristics of current heart failure patients admitted to internal medicine vs. cardiology hospital units: the VASCO study

The majority of patients hospitalized for heart failure (HF) are admitted to internal medicine (IM) rather than to cardiology (CA) units, but to date few studies have analyzed the characteristics of these two ...

Elisa Ricciardi, Giovanni La Malfa, Giulia Guglielmi… in Internal and Emergency Medicine (2020)

Article

Effect of Bempedoic Acid on Serum Uric Acid and Related Outcomes: A Systematic Review and Meta-analysis of the available Phase 2 and Phase 3 Clinical Studies

Bempedoic acid (ETC-1002) is a first-in-class lipid-lowering agent recently approved by the United States (US) Food and Drug Administration (FDA) and the European Medicines Agency (EMA) for commercialization.

Arrigo F. G. Cicero, Roberto Pontremoli, Federica Fogacci, Francesca Viazzi… in Drug Safety (2020)

Article

Uric acid in CKD: has the jury come to the verdict?

Epidemiological studies show that hyperuricemia independently predicts the development of chronic kidney disease (CKD) in individuals with normal kidney function both in the general population and in subjects ...

Barbara Bonino, Giovanna Leoncini, Elisa Russo, Roberto Pontremoli… in Journal of Nephrology (2020)

Article

Effects of dual inhibition of renin–angiotensin–aldosterone system on cardiovascular and renal outcomes: balancing the risks and the benefits

Chronic kidney disease is a worldwide health problem often burdened by severe cardiovascular complications. Hypertension represents one of the most important risk factor in affecting cardiovascular profile of ...

Giuliano Tocci, Barbara Citoni, Vivianne Presta… in Internal and Emergency Medicine (2020)

Article

Italian Society of Arterial Hypertension (SIIA) Position Paper on the Role of Renal Denervation in the Management of the Difficult-to-Treat Hypertensive Patient

Renal denervation is a device-based procedure for hypertension for which safety and efficacy has been demonstrated. At present, its clinical use is still matter of debate, despite the most recent clinical tria...

Rosa Maria Bruno, Stefano Taddei… in High Blood Pressure & Cardiovascular Preve… (2020)

Article

Blood pressure phenotype: an evolving picture

Giovanna Leoncini, Francesca Viazzi, Barbara Bonino… in Internal and Emergency Medicine (2020)