-
Article
Evaluation of arteriovenous fistula for hemodialysis with a new generation digital stethoscope: a pilot study
The management of complications of arteriovenous fistula (AVF) for hemodialysis, principally stenosis, remains a major challenge for clinicians with a substantial impact on health resources. Stenosis not infre...
-
Article
The Role of prEoperative ultraSonography on patenCy of native arteriovenoUs accEss: RESCUE study protocol
-
Article
Marinobufagenin, left ventricular geometry and cardiac dysfunction in end-stage kidney disease patients
Left ventricular hypertrophy (LVH) is remarkably prevalent among end-stage kidney disease (ESKD) on chronic dialysis and has a strong prognostic value for adverse outcomes. In experimental models, the endogeno...
-
Article
Hyperkalemia excursions and risk of mortality and hospitalizations in hemodialysis patients: results from DOPPS-Italy
-
Article
Open AccessSmoking habit as a risk amplifier in chronic kidney disease patients
Several studies showed the association between non-traditional risk factors [proteinuria and estimated Glomerular Filtration Rate (eGFR)] and cardiovascular (CV) and renal outcomes. Nevertheless, the etiologic...
-
Article
Serum gamma-glutamyltransferase, oxidized LDL and mortality in the elderly
Serum gamma-glutamyltransferase (GGT) is a liver enzyme involved in the metabolism of glutathione (GSH), a major antioxidant in humans. GGT is a risk factor for mortality in young and middle-aged individuals b...
-
Article
Increased circulating Cathepsin-K levels reflect PTH control in chronic hemodialysis patients
Mineral bone disease (MBD) is remarkably frequent among chronic hemodialysis (HD) patients. In this setting, deranged PTH levels portend an adjunctive risk of worsen outcomes. Various evidence exists demonstra...
-
Article
Open AccessOCT angiography metrics predict intradialytic hypotension episodes in chronic hemodialysis patients: a pilot, prospective study
In chronic hemodialysis (HD) patients, intradialytic hypotension (IDH) is a complication that increases mortality risk. We run a pilot study to analyzing possible relationships between optical coherence tomogr...
-
Article
Cathepsin-K is a potential cardiovascular risk biomarker in prevalent hemodialysis patients
Cardiovascular (CV) disease remains the leading cause of mortality among end-stage kidney disease (ESKD) patients. Cathepsin-K (CatK), a small cysteine protease involved in bone and extracellular matrix remode...
-
Article
RAS inhibition modulates kynurenine levels in a CKD population with and without type 2 diabetes mellitus
Kynurenine pathway of tryptophan metabolism is involved in the pathophysiology of chronic kidney disease (CKD) and diabetes mellitus, mainly through the inflammation-induced activity of indoleamine 2,3-dioxyge...
-
Article
Kidney function and cognitive decline in frail elderly: two faces of the same coin?
Cognitive and renal impairment are pervasive among elderly frails, a high-risk, geriatric sub-population with peculiar clinical characteristics. In a series of frail individuals with non-advanced chronic kidne...
-
Article
Good-quality research in rare diseases: trials and tribulations
Despite the fact that rare diseases affecting the kidney are not as uncommon as generally believed, proper clinical guidelines for guiding therapeutic management are scarce or absent owing to the overall lack ...
-
Article
Priority topics for European multidisciplinary guidelines on the management of chronic kidney disease in older adults
To identify and prioritize potential topics to be addressed in the development of European multidisciplinary guidelines on the management of chronic kidney disease stage 3b–5 in older patients.
-
Reference Work Entry In depth
Pulmonary Pressure as a Novel Prognostic Biomarker in Renal Patients
Renal patients are notoriously at high risk for cardiovascular complications, but such risk is not fully explained by traditional and chronic kidney disease (CKD)-related risk factors. New prognostic biomarker...
-
Reference Work Entry In depth
Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology
Neutrophil gelatinase-associated lipocalin (NGAL) is a small 25-kD peptide belonging to the lipocalin superfamily. It mainly binds to siderophores, iron-carrying molecules which are essential to bacterial and ...
-
Reference Work Entry In depth
Kidney and Neoplastic Disease: Overview with a Particular Interest to Interpretation of Cancer Biomarkers
Tumor markers represent useful tools in diagnosis and clinical management of patients with cancer, because they are easy to use, minimally invasive, and easily measured either by blood or urine. Unfortunately,...
-
Article
Erratum to: Physical exercise programs in CKD: lights, shades and perspectives
-
Article
Physical excercise programs in CKD: lights, shades and perspectives: a position paper of the “Physical Exercise in CKD Study Group” of the Italian Society of Nephrology
In the general population, moderate exercise is associated with several health benefits including a decreased risk of obesity, coronary heart disease, stroke, certain types of cancer and all-cause mortality. I...
-
Living Reference Work Entry In depth
Overview of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker in Nephrology
Neutrophil gelatinase-associated lipocalin (NGAL) is a small 25-kD peptide belonging to the lipocalin superfamily. It mainly binds to siderophores, iron-carrying molecules which are essential to bacterial and ...
-
Living Reference Work Entry In depth
Pulmonary Pressure as a Novel Prognostic Biomarker in Renal Patients
Renal patients are notoriously at high risk for cardiovascular complications, but such risk is not fully explained by traditional and chronic kidney disease (CKD)-related risk factors. New prognostic biomarker...
