-
Article
Open AccessPartial dechlorination of 2,4,4′-trichlorobiphenyl (PCB 28) mediated by recombinant human CYP1A2
-
Article
Open AccessTen years after: findings from the medical surveillance program on Health Effects in High-Level Exposure to PCB (HELPcB)
After the detection of high environmental and occupational exposure to polychlorinated biphenyls (PCBs) in a German recycling company for transformers and capacitors in 2010, the multidisciplinary medical surv...
-
Article
Open AccessThe role of the DC component in human perception of AC–DC hybrid electric fields and a comparison with the AC component
As part of the energy transition in Germany, high-voltage overhead power lines will be operated using hybrid systems that combine alternating and direct current (AC and DC). The degree to which humans perceive...
-
Article
Open AccessGesundheitsschutz und Klimawandel erfordern ambitionierte Grenzwerte für Luftschadstoffe in Europa
Die Weltgesundheitsorganisation (WHO) hat aufgrund wissenschaftlicher Ergebnisse die Richtwerte zur Luftqualität 2021 verschärft. Es wurde eine deutliche Absenkung der Jahresmittelwerte von Feinstaub (Partikel...
-
Article
Open AccessSelf-Reported Pre-Pandemic Physical Activity and Likelihood of COVID-19 Infection: Data from the First Wave of the CoCo-Fakt Survey
To investigate the potential protective role of exercise on the odds of COVID-19 infection in unvaccinated contact persons (CPs) who were at higher risk of infection due to confirmed contact with infected pers...
-
Article
Open AccessBlood lead monitoring in a former mining area in Euskirchen, Germany: results of a representative random sample in 3- to 17-year-old children and minors
Heavy metal residues in former mining areas can pose a burden to the local environment and population even decades after closure of the mining sites. In the North Rhine-Westphalian (Germany) communities of Mec...
-
Article
Open AccessThe human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro
Short-term inhalation of occupationally relevant ultrafine zinc/copper (Zn/Cu) containing welding fumes has been shown to induce subclinical systemic inflammation, associated with an elevated risk for cardiova...
-
Article
Open AccessThe role of the AC component in human perception of AC–DC hybrid electric fields
Electric energy is essential to today’s society. To cope with global higher demand while minimizing land use, efficient high voltage direct current (HVDC) power lines are planned to be mounted on existing alte...
-
Article
Open AccessDiscrepancy of particle passage in 101 mask batches during the first year of the Covid-19 pandemic in Germany
During the first wave of Covid-19 infections in Germany in April 2020, clinics reported a shortage of filtering face masks with aerosol retention> 94% (FFP2 & 3, KN95, N95). Companies all over the world increa...
-
Article
Open AccessHidden ileostomy as a rescue procedure in major colorectal surgeries: a novel technique to prevent re-laparotomy in anastomotic leak cases
Anastomotic leak is a major cause of morbidity and mortality of patients worldwide, and it has remained stable over the last years. Routine construction of protective ileostomy is associated with stoma and neg...
-
Article
Open AccessThe pupillary light reflex (PLR) as a marker for the ability to work or drive – a feasibility study
The PLR (pupillary light reflex) can be a marker for pathological medical conditions, such as neurodegenerative or mental health disorders and diseases as well as marker for physiological alterations, such as ...
-
Article
Open AccessHuman detection thresholds of DC, AC, and hybrid electric fields: a double-blind study
In the course of the ongoing transition of electric energy systems, transmission corridors are often upgraded to higher voltages and other technologies leading to another quality of human exposure. The study a...
-
Article
Open AccessLongitudinal changes in telomere length in PCB-exposed individuals: interaction with CMV infection
We recently demonstrated a significant shortening of age-adapted telomere length (TL) in lymphocytes of polychlorinated biphenyls (PCB)-exposed individuals. Here, we analyzed TL in individuals of the same PCB-...
-
Chapter
Schadstoffbelastung der Außenluft – Prävalenz, Bedeutung und Implikationen für die Prävention und Gesundheitsförderung
Der Großteil der Schadstoffe in der Außenluft hat seinen Ursprung in der Verbrennung fossiler Brennstoffe im Straßenverkehr. Neben den Stickoxiden spielen vor allem die Feinstäube mit einer Partikelgröße <2,5 ...
-
Reference Work Entry In depth
Medical Aspects of Traffic Exhaust Regulations
Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...
-
Living Reference Work Entry In depth
Medical Aspects of Traffic Exhaust Regulations
Traffic exhaust emissions are a major driver of premature diseases and deaths. A reduction of traffic exhaust emissions can be supported by a continuous climate-friendly transportation policy. The European Green ...
-
Article
Open AccessBlood collection technique, anticoagulants and storing temperature have minor effects on the isolation of polymorphonuclear neutrophils
In the isolation of polymorphonuclear neutrophils (PMNs) the technique and other external factors can have great influence on the quality and quantity of isolated neutrophils. To elucidate the influence of the...
-
Article
Dirty deeds done dirt cheap: sensitization of prostate cancer cells to abiraterone treatment using hydroxylated polychlorinated biphenyls
Effective targeting of androgen biosynthesis by the 17α-hydroxylase/17,20-lyase inhibitor abiraterone prolongs survival in a variety of prostate cancer patients. However, resistance to abiraterone treatment oc...
-
Article
Open AccessDoes stigmatization moderate the association between intention and implementation of learned prevention-strategies at work after a depressive episode? – a cross-sectional pilot study
A depressive episode is a frequent reason for production loss due to long periods of absence at work. To maintain work ability after depression, affected employees need to implement learned co** strategies f...
-
Article
Open AccessInvestigating the association between occupational exposure to asbestos and ovarian carcinoma: results from a pilot study in Germany
The aim of this pilot study was to assess the feasibility of a large-scale epidemiologic investigation elucidating the quantitative association between occupational exposure to asbestos and ovarian cancer in f...
