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Dirty deeds done dirt cheap: sensitization of prostate cancer cells to abiraterone treatment using hydroxylated polychlorinated biphenyls
Effective targeting of androgen biosynthesis by the 17α-hydroxylase/17,20-lyase inhibitor abiraterone prolongs survival in a variety of prostate cancer patients. However, resistance to abiraterone treatment oc...
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Open AccessTelomerase gene expression bioassays indicate metabolic activation of genotoxic lower chlorinated polychlorinated biphenyls
Polychlorinated biphenyls (PCBs) are ubiquitously occurring pollutants with different chemical and toxicological properties. In this study we evaluated blood plasma samples of two PCB-exposed cohorts for their...
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Open AccessAccess site complications after transfemoral aortic valve implantation - a comparison of Manta and ProGlide
Despite decreasing sheath diameter, access site bleeding and vascular complications are still a major concern in transfemoral aortic valve implantation (TAVI), and may increase morbidity and even increase mort...
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Chapter
Acute Myeloid Leukemia with Recurrent Genetic Abnormalities: Part I Cytogenetic Abnormalities
Acute myeloid leukemia (AML) is a clonal malignant neoplasm of myeloid cell lineage primarily involving the peripheral blood and bone marrow, although other tissue manifestations can be seen. AML subty** is ...
