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    Article

    Peptide Composition and Identification of a Peptide with Anti-Inflammatory and Antiplatelet Properties in Cattle Prostate Extract

    An attempt to identify the peptide structure of bovine prostate extract using water/vinegar technology followed by tangential ultrafiltration is described. Protein-peptide components with known functional acti...

    S. A. Savel’ev, A. G. Mittenberg, T. I. Aref’eva in Pharmaceutical Chemistry Journal (2024)

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    Article

    Influence of Manufacturing Technology on the Properties of Active Pharmaceutical Ingredients of Prostate Extract

    Important peculiarities of various technologies used for manufacturing the API of prostate extract that determine different qualitative characteristics of the final product are described. Data on the physicoch...

    S. A. Savel’ev, M. Yu. Dorosh, T. I. Oparina in Pharmaceutical Chemistry Journal (2022)

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    Article

    On the Discontinuity of Annuity Curves in Drosophila melanogaster Wild Type Strain Canton-S. IV. The Effect of Rearing at Low Temperature during the Early Imaginal Stage

    The rearing of Drosophila fruit flies at a temperature 5–7°C lower than the standard level until day 13 (or day 22) of the imaginal period enabled an increase of the individual insect lifespan. The positive effec...

    I. B. Bychkovskaya, S. V. Mylnikov, T. I. Oparina in Advances in Gerontology (2017)

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    Article

    Discreteness of survival curves. I. Deviations from the Gompertz law in Drosophila melanogaster Canton-S strain

    Analysis of the age-specific mortality dynamics in the male imago of the Drosophila melanogaster Canton-S strain demonstrated pronounced deviations from the Gompertz law. Four successive observations carried out ...

    S. V. Mylnikov, T. I. Oparina, I. B. Bychkovskaia in Advances in Gerontology (2016)

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    Article

    The effect of a derivative of indole morphine administered during the induction of labor on the activity of antioxidant enzymes in the brains of fetal rabbits

    We studied the effects of a derivative of indole morphine (Trisan) during induction of labor on the activity of enzymes of antioxidant defense in the brains of fetuses that developed under normal (intact) and ...

    M. M. Gabaeva, L. A. Nazarova, E. V. Baziyan, A. A. Yakovleva in Neurochemical Journal (2011)

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    Article

    Effect of Chronic Inhalation of Toluene and Dioxane on Activity of Free Radical Processes in Rat Ovaries and Brain

    The effects of toluene and dioxane inhalations on the intensity of free radical oxidation in rat ovaries and brain cortex were studied. Both toxins in a dose 10-fold surpassimg the maximum permissible concentr...

    S. O. Burmistrov, A. V. Arutyunyan in Bulletin of Experimental Biology and Medic… (2001)

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    Article

    Effects of Peptides on Generation of Reactive Oxygen Species in Subcellular Fractions of Drosophila Melanogaster

    We studied the effects of Epithalon (Ala-Glu-Asp-Gly) and Vilon (Lys-Glu) on free radical processes in highly inbred HA+line of Drosophila melanogaster. Vilon inhibited generation of reactive oxygen species in mi...

    V. Kh. Khavinson, S. V. Myl'nikov in Bulletin of Experimental Biology and Medic… (2001)

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    Article

    Free Oxygen Radicals and the Antioxidant System in Healthy Full-Term Neonates

    M. N. Kosov, V. M. Prokopenko, T. I. Oparina, I. I. Evsyukova in Human Physiology (2001)

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    Article

    Mechanism of mildronate effect on rabbit fetuses develo** under conditions of placental insufficiency

    Mildronate, 3-(2,2,2-trimethyl hydrasinium) propionate dehydrate, a drug producing antihypoxic and selective vasodilating (in vascular spasm) effects, improves the status of rabbit fetuses with chronic intraut...

    E. I. Krivtsova, N. G. Pavlova in Bulletin of Experimental Biology and Medic… (1998)

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    Article

    Effect of radiation from personal computer monitor on free-radical processes in rats

    Radiation from a personal computer monitor reduces antioxidant activity and the contents of diene conjugates and Schiff bases in rat serum and has no effect on chemiluminescence and the content of carbonyl der...

    V. N. Anisimov, A. V. Arutyunyan in Bulletin of Experimental Biology and Medic… (1997)

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    Chapter

    The Disturbances of the Hypothalamic Circadian Rhythm Regulation in Female Rats Under the Influence of Xenobiotics

    The reproductive system is one of the most sensitive systems of the organism that reacts on environmental pollution. Former experiments (1,2) led to the conclusion that independent of nature ecologically unfav...

    A. V. Arutjunyan, M. G. Stepanov, A. V. Korenevsky, V. M. Prokopenko in Neurochemistry (1997)

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    Article

    Effect of superoxide dismutase on convulsive seizures in rat models of epilepsy

    Intravenous injections of superoxide dismutase into rats with amygdaline kindling mitigated spontaneous and electrostimulation-induced epileptic seizures and raised the thresholds of electric current for their...

    I. V. Gusakov, B. P. Sharonov, T. I. Oparina in Bulletin of Experimental Biology and Medic… (1995)