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Article
Peptide Composition and Identification of a Peptide with Anti-Inflammatory and Antiplatelet Properties in Cattle Prostate Extract
An attempt to identify the peptide structure of bovine prostate extract using water/vinegar technology followed by tangential ultrafiltration is described. Protein-peptide components with known functional acti...
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Article
Influence of Manufacturing Technology on the Properties of Active Pharmaceutical Ingredients of Prostate Extract
Important peculiarities of various technologies used for manufacturing the API of prostate extract that determine different qualitative characteristics of the final product are described. Data on the physicoch...
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Article
On the Discontinuity of Annuity Curves in Drosophila melanogaster Wild Type Strain Canton-S. IV. The Effect of Rearing at Low Temperature during the Early Imaginal Stage
The rearing of Drosophila fruit flies at a temperature 5–7°C lower than the standard level until day 13 (or day 22) of the imaginal period enabled an increase of the individual insect lifespan. The positive effec...
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Article
Discreteness of survival curves. I. Deviations from the Gompertz law in Drosophila melanogaster Canton-S strain
Analysis of the age-specific mortality dynamics in the male imago of the Drosophila melanogaster Canton-S strain demonstrated pronounced deviations from the Gompertz law. Four successive observations carried out ...
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Article
The effect of a derivative of indole morphine administered during the induction of labor on the activity of antioxidant enzymes in the brains of fetal rabbits
We studied the effects of a derivative of indole morphine (Trisan) during induction of labor on the activity of enzymes of antioxidant defense in the brains of fetuses that developed under normal (intact) and ...
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Article
Effect of Chronic Inhalation of Toluene and Dioxane on Activity of Free Radical Processes in Rat Ovaries and Brain
The effects of toluene and dioxane inhalations on the intensity of free radical oxidation in rat ovaries and brain cortex were studied. Both toxins in a dose 10-fold surpassimg the maximum permissible concentr...
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Article
Effects of Peptides on Generation of Reactive Oxygen Species in Subcellular Fractions of Drosophila Melanogaster
We studied the effects of Epithalon (Ala-Glu-Asp-Gly) and Vilon (Lys-Glu) on free radical processes in highly inbred HA+line of Drosophila melanogaster. Vilon inhibited generation of reactive oxygen species in mi...
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Article
Free Oxygen Radicals and the Antioxidant System in Healthy Full-Term Neonates
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Article
Mechanism of mildronate effect on rabbit fetuses develo** under conditions of placental insufficiency
Mildronate, 3-(2,2,2-trimethyl hydrasinium) propionate dehydrate, a drug producing antihypoxic and selective vasodilating (in vascular spasm) effects, improves the status of rabbit fetuses with chronic intraut...
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Article
Effect of radiation from personal computer monitor on free-radical processes in rats
Radiation from a personal computer monitor reduces antioxidant activity and the contents of diene conjugates and Schiff bases in rat serum and has no effect on chemiluminescence and the content of carbonyl der...
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The Disturbances of the Hypothalamic Circadian Rhythm Regulation in Female Rats Under the Influence of Xenobiotics
The reproductive system is one of the most sensitive systems of the organism that reacts on environmental pollution. Former experiments (1,2) led to the conclusion that independent of nature ecologically unfav...
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Article
Effect of superoxide dismutase on convulsive seizures in rat models of epilepsy
Intravenous injections of superoxide dismutase into rats with amygdaline kindling mitigated spontaneous and electrostimulation-induced epileptic seizures and raised the thresholds of electric current for their...