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The effect of a derivative of indole morphine administered during the induction of labor on the activity of antioxidant enzymes in the brains of fetal rabbits

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Abstract

We studied the effects of a derivative of indole morphine (Trisan) during induction of labor on the activity of enzymes of antioxidant defense in the brains of fetuses that developed under normal (intact) and disturbed (experimental) placental blood circulation. We show that Trisan has antihypoxic and moderate antioxidant characteristics and decreased intranatal oxidative stress in the CNS of intact and experimental fetuses.

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Authors and Affiliations

  1. Ott Research Institute of Obsterics and Gynecology, North-Western Division, Russian Academy of Medical Sciences, St. Petersburg, Russia

    M. M. Gabaeva, L. A. Nazarova, E. V. Baziyan, A. A. Yakovleva, T. I. Oparina, V. M. Prokopenko, V. L. Pastushenkov, N. N. Konstantinova & N. G. Pavlova

Authors
  1. M. M. Gabaeva
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  2. L. A. Nazarova
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  3. E. V. Baziyan
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  4. A. A. Yakovleva
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  5. T. I. Oparina
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  6. V. M. Prokopenko
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  7. V. L. Pastushenkov
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  8. N. N. Konstantinova
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  9. N. G. Pavlova
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Corresponding author

Correspondence to L. A. Nazarova.

Additional information

Original Russian Text © M.M. Gabaeva, L.A. Nazarova, E.V. Baziyan, A.A. Yakovleva, T.I. Oparina, V.M. Prokopenko, V.L. Pastushenkov, N.N. Konstantinova, N.G. Pavlova, 2011, published in Neirokhimiya, 2011, Vol. 28, No. 3, pp. 232–235.

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Gabaeva, M.M., Nazarova, L.A., Baziyan, E.V. et al. The effect of a derivative of indole morphine administered during the induction of labor on the activity of antioxidant enzymes in the brains of fetal rabbits. Neurochem. J. 5, 205–207 (2011). https://doi.org/10.1134/S1819712411030020

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  • DOI: https://doi.org/10.1134/S1819712411030020

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