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Article
Open AccessAutoantibodies against P29ING4 are associated with complex regional pain syndrome
Complex regional pain syndrome (CRPS) is a complication following trauma or surgery and may be difficult to diagnose since biomarkers are lacking. Using protein array technology, we found antibodies binding to...
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Article
Optically excited structural transition in atomic wires on surfaces at the quantum limit
A structural transition in an atomic indium wire on a silicon substrate proceeds as fast as the indium atom vibrations and is facilitated by strong In–Si interface bonds.
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Article
Arthroscopic treatment for ulnar-sided TFCC-tears
Ruptures of ulnar-sided triangular fibrocartilaginous complex (TFCC) often occur in cases of trauma. Golden standard for diagnosis is the arthroscopy of the wrist. TFCC lesions are classified according to thei...
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Article
Open AccessDefective removal of ribonucleotides from DNA promotes systemic lupus erythematosus
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Article
Association of ferritin antibodies with Takayasu arteritis
Takayasu arteritis (TA) is difficult to diagnose because diagnostic biomarkers have not yet been established. In a previous study, we detected autoantibodies against the human ferritin heavy chain protein (HFC...
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Article
Genetic association of miRNA-146a with systemic lupus erythematosus in Europeans through decreased expression of the gene
A recent genome-wide association study revealed a variant (rs2431697) in an intergenic region, between the pituitary tumor-transforming 1 (PTTG1) and microRNA (miR-146a) genes, associated with systemic lupus eryt...
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Article
The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis
Regulatory T cells (Tregs) are crucial in the maintenance of the immune tolerance and seem to have an important role in systemic sclerosis (SSc). The interleukin 2 receptor α (IL2RA) is an important Treg marker, ...
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Article
Open AccessIdentification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy
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Article
Open AccessA replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort
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Article
Association of UCP2 −866 G/A polymorphism with chronic inflammatory diseases
We reported earlier that two mitochondrial gene polymorphisms, UCP2 –866 G/A (rs659366) and mtDNA nt13708 G/A (rs28359178), are associated with multiple sclerosis (MS). Here we aim to investigate whether these fu...
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Article
Replication of the TNFSF4 (OX40L) promoter region association with systemic lupus erythematosus
The tumor necrosis factor ligand superfamily member 4 gene (TNFSF4) encodes the OX40 ligand (OX40L), a costimulatory molecule involved in T-cell activation. A recent study demonstrated the association of TNFSF4 h...
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Article
Association of common variable immunodeficiency with vitamin B6 deficiency
To study the prevalence of vitamin B6 deficiency in common variable immunodeficiency and the impact of vitamin B6 supplementation on immune function in the disorder.
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Article
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
Genetic variation in the interferon regulatory factor 5 (IRF5) gene affects systemic lupus erythematosus (SLE) susceptibility. However, association is complex and incompletely defined. We obtained fourteen Europe...
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Article
Bias in association studies of systemic lupus erythematosus susceptibility due to geographical variation in the frequency of a programmed cell death 1 polymorphism across Europe
We obtained eight collections of DNA samples from ethnically matched systemic lupus erythematosus (SLE) patients and controls from five European countries totaling 783 patients and 1210 controls. A highly sign...
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Article
Association of multiple sclerosis with ILT6 deficiency
Multiple sclerosis (MS) is an autoimmune disorder of multifactorial etiology. Family studies have shown strong genetic contributions. Linkage analyses have revealed several regions harboring risk genes includi...
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Article
Femtosecond pulse sha** in the mid infrared by difference-frequency mixing
The generation of programmable complex femtosecond pulses in the mid infrared (3–10 μm) with high precision is reported. Designed pulse shapes in the near infrared (1–1.6 μm) are transferred to the mid infrare...
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Article
Enhanced frequency of a PTPRC (CD45) exon A mutation (77C→G) in systemic sclerosis
A point mutation in exon A (C to G transversion at position 77) of human PTPRC (CD45) has recently been associated with the development of multiple sclerosis (MS) for at least a subgroup of patients. In the pr...
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Article
Elevated anti-serum amyloid P component (SAP) antibodies in SLE patients
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Article
Amplification of tailored white-light continuum
The transfer of phase and amplitude modulation of the seed continuum in an optical parametric amplification process is investigated. A white-light continuum serves as the seed in non-collinear optical parametr...
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Article
Rheumatoid factors in systemic lupus erythematosus: association with clinical and laboratory parameters
The prevalence and clinical and laboratory associations of IgM, IgG and IgA rheumatoid factors (RF) were determined in 352 patients with systemic lupus erythematosus (SLE). IgM, IgG, and IgA class RF were det...
