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Article
Soluble Syndecan-1: A Novel Biomarker of Small Bowel Mucosal Damage in Children with Celiac Disease
Syndecan-1 (SDC1) is essential for maintaining normal epithelial barrier. Shedding of SDC1 ectodomain, reflected by serum soluble syndecan-1 (SSDC1) levels, is regulated by inflammation. Increased intestinal perm...
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Article
New automated indirect immunofluorescent antinuclear antibody testing compares well with established manual immunofluorescent screening and titration for antinuclear antibody on HEp-2 cells
The IIF using the HEp-2 cell substrate should be still considered the “gold standard” techniques for determination of antinuclear antibody (ANA). Standardization and automation can be considered to be still in...
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Article
Comment on “Microbial Enzymes as Substitutes of Chemical Additives in Baking Wheat Flour—Part II: Combined Effects of Nine Enzymes on Dough Rheology [M.M. Bueno, R.C.S. Thys and R.C. Rodrigues (2016), Food and Bioprocess Technology, 9(9), 1598–1611]”
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Article
A fully automated IIF system for the detection of antinuclear antibodies and antineutrophil cytoplasmic antibodies
Indirect immunofluorescence (IIF) is the main technique for the detection of antinuclear antibodies (ANA) and antineutrophil cytoplasmic antibodies (ANCA). The fully automated IIF processor HELIOS® is the first I...
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Article
Numerical analysis of draw bending of load-adapted sheet metal profiles
In comparison to traditional roll forming processes, draw bending process represents a flexible and inexpensive production of open sheet metal profiles. Draw bending technologies allow the fabrication of load-...
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Chapter and Conference Paper
Consideration of the Machine Influence on Multistage Sheet Metal Forming Processes
Metal forming processes are highly affected by the properties of the forming machine. In multistage processes, the force path curve of each stage is influenced by the surrounding stages. This research focuses ...
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Chapter
New Strategies in Finite Element Analysis of Material Processing
Under the supervision of Professor Bernd-Arno Behrens, the head of the Institute of Metal Forming and Metal-Forming Machines (IFUM), three PhD projects were carried out during the span of the Research Training...
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Article
Aluminum Thermo Compression Bonding Characterization
Wafer level bonding is an important technology for the manufacturing of numerous Microelectromechanical Systems. In this work the aluminum thermo-compression wafer bonding is characterized. The effects and sig...
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Chapter and Conference Paper
Numerical Investigations of the Strain-Adaptive Bone Remodeling in the Prosthetic Pelvis
Bone remodeling due to stress shielding is a major cause of hip implants aseptic loosening. Previously, investigations on this phenomenon were based mainly on clinical observations. Currently, the finite eleme...
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Article
Effects of Bonding Process Parameters on Wafer-to-Wafer Alignment Accuracy in Benzocyclobutene (BCB) Dielectric Wafer Bonding
Wafer-level three-dimensional (3D) integration is an emerging technology to increase the performance and functionality of integrated circuits (ICs). Aligned wafer-to-wafer bonding with dielectric polymer layer...
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Article
Fundamental Limits for 3D Wafer-to-Wafer Alignment Accuracy
Wafer-level three-dimensional (3D) integration as an emerging architecture for future chips offers high interconnect performance by reducing delays of global interconnects and high functionality with heterogen...
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Article
Association of initial response to prednisone treatment in childhood acute lymphoblastic leukaemia and polymorphisms within the tumour necrosis factor and the interleukin-10 genes
Plasma levels of TNF and IL-10 have been associated with therapy outcome in haematological malignancies and are influenced by genetic variation due to germline polymorphisms within the TNF and IL-10 genes. Differ...
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Article
Rheumatoid factors in systemic lupus erythematosus: association with clinical and laboratory parameters
The prevalence and clinical and laboratory associations of IgM, IgG and IgA rheumatoid factors (RF) were determined in 352 patients with systemic lupus erythematosus (SLE). IgM, IgG, and IgA class RF were det...
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Article
IgM anti-dsDNA antibodies in systemic lupus erythematosus: negative association with nephritis
Antibodies against dsDNA of the IgM class were measured in sera of 352 patients with systemic lupus erythematosus, 81 blood donors and 189 patients with rheumatoid arthritis using a new ELISA based on human r...
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Article
Association of IgA anti-dsDNA antibodies with vasculitis and disease activity in systemic lupus erythematosus
Previously it has been suggested that the presence of antibodies against dsDNA of the IgA class may define a subset of systemic lupus erythematosus (SLE) patients suffering from nephritis and arthritis. There...
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Article
Zum dsDNA-Antikörpernachweis in der Diagnostik des Systemischen Lupus erythematodes – Vergleichende Untersuchungen zur diagnostischen Effizienz dreier ELISA-Verfahren mit unterschiedlichen Antigenen und einem Crithidia-Iuciliae-Immunfluoreszenztest
Antibodies to double-stranded DNA (anti-dsDNA, dsDNA-Ab) are frequently found in systemic lupus erythematosus (SLE), especially during active disease and differ with respect to immunoglobulin class and avidit...
