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Article
Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis
Genetic biomarkers could be useful for orienting treatment of patients with rheumatoid arthritis (RA), but none has been convincingly validated yet. Putative biomarkers include 14 single nucleotide polymorphis...
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Article
The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis
Regulatory T cells (Tregs) are crucial in the maintenance of the immune tolerance and seem to have an important role in systemic sclerosis (SSc). The interleukin 2 receptor α (IL2RA) is an important Treg marker, ...
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Article
Open AccessVariants of PBEF predispose to systemic sclerosis and pulmonary arterial hypertension development
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Open AccessIdentification of novel genetic markers associated with the clinical phenotypes of systemic sclerosis through a genome wide association strategy
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Open AccessA replication study confirms the association of TNFSF4 (OX40L) polymorphisms with Systemic Sclerosis in a large European cohort
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Open AccessPolymorphisms in the interleukin 4, interleukin 13 and corresponding receptor genes are not associated with Systemic Sclerosis and do not influence gene expression
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Article
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
Genetic variation in the interferon regulatory factor 5 (IRF5) gene affects systemic lupus erythematosus (SLE) susceptibility. However, association is complex and incompletely defined. We obtained fourteen Europe...
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Article
Nanofiller effect on the glass transition of a polyurethane
The effect of silica nanofiller on the glass transition of a polyurethane was studied by DSC. The pristine polymer exhibits a single glass transition at about –10°C. Uniform SiO2 spheres with different average...
